Publications
2017
Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity.
Li J,
Casteels T,
Frogne T,
Ingvorsen C,
Honoré C,
Courtney M,
Huber KV,
Schmitner N,
Kimmel RA,
Romanov RA,
Sturtzel C,
Lardeau CH,
Klughammer J,
Farlik M,
Sdelci S,
Vieira A,
Avolio F,
Briand F,
Baburin I,
Májek P,
Pauler FM,
Penz T,
Stukalov A,
Gridling M,
Parapatics K,
Barbieux C,
Berishvili E,
Spittler A,
Colinge J,
Bennett KL,
Hering S,
Sulpice T,
Bock C,
Distel M,
Harkany T,
Meyer D,
Superti-Furga G,
Collombat P,
Hecksher-Sørensen J,
Kubicek S.
Cell. 2017 Jan 12;168(1-2):86-100.e15. doi: 10.1016/j.cell.2016.11.010. Epub 2016 Dec 1.
2017
Pooled CRISPR screening with single-cell transcriptome readout.
Datlinger P,
Rendeiro AF,
Schmidl C,
Krausgruber T,
Traxler P,
Klughammer J,
Schuster LC,
Kuchler A,
Alpar D,
Bock C.
Nat Methods. 2017 Mar;14(3):297-301. doi: 10.1038/nmeth.4177. Epub 2017 Jan 18.
2017
Comparative Genome Sequencing Reveals Within-Host Genetic Changes in Neisseria meningitidis during Invasive Disease.
Klughammer J,
Dittrich M,
Blom J,
Mitesser V,
Vogel U,
Frosch M,
Goesmann A,
Müller T,
Schoen C.
PLoS One. 2017 Jan 12;12(1):e0169892. doi: 10.1371/journal.pone.0169892. eCollection 2017.
2017
DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma.
Sheffield NC,
Pierron G,
Klughammer J,
Datlinger P,
Schönegger A,
Schuster M,
Hadler J,
Surdez D,
Guillemot D,
Lapouble E,
Freneaux P,
Champigneulle J,
Bouvier R,
Walder D,
Ambros IM,
Hutter C,
Sorz E,
Amaral AT,
de Álava E,
Schallmoser K,
Strunk D,
Rinner B,
Liegl-Atzwanger B,
Huppertz B,
Leithner A,
de Pinieux G,
Terrier P,
Laurence V,
Michon J,
Ladenstein R,
Holter W,
Windhager R,
Dirksen U,
Ambros PF,
Delattre O,
Kovar H,
Bock C,
Tomazou EM.
Nat Med. 2017 Mar;23(3):386-395. doi: 10.1038/nm.4273. Epub 2017 Jan 30.
2017
Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes.
Romanov RA,
Zeisel A,
Bakker J,
Girach F,
Hellysaz A,
Tomer R,
Alpár A,
Mulder J,
Clotman F,
Keimpema E,
Hsueh B,
Crow AK,
Martens H,
Schwindling C,
Calvigioni D,
Bains JS,
Máté Z,
Szabó G,
Yanagawa Y,
Zhang MD,
Rendeiro A,
Farlik M,
Uhlén M,
Wulff P,
Bock C,
Broberger C,
Deisseroth K,
Hökfelt T,
Linnarsson S,
Horvath TL,
Harkany T.
Nat Neurosci. 2017 Feb;20(2):176-188. doi: 10.1038/nn.4462. Epub 2016 Dec 19.
2017
Malondialdehyde epitopes are sterile mediators of hepatic inflammation in hypercholesterolemic mice.
Busch CJ,
Hendrikx T,
Weismann D,
Jäckel S,
Walenbergh SM,
Rendeiro AF,
Weißer J,
Puhm F,
Hladik A,
Göderle L,
Papac-Milicevic N,
Haas G,
Millischer V,
Subramaniam S,
Knapp S,
Bennett KL,
Bock C,
Reinhardt C,
Shiri-Sverdlov R,
Binder CJ.
Hepatology. 2017 Apr;65(4):1181-1195. doi: 10.1002/hep.28970. Epub 2017 Feb 3.
2017
Genomic and transcriptional landscape of P2RY8-CRLF2-positive childhood acute lymphoblastic leukemia.
Vesely C,
Frech C,
Eckert C,
Cario G,
Mecklenbräuker A,
Zur Stadt U,
Nebral K,
Kraler F,
Fischer S,
Attarbaschi A,
Schuster M,
Bock C,
Cavé H,
von Stackelberg A,
Schrappe M,
Horstmann MA,
Mann G,
Haas OA,
Panzer-Grümayer R.
Leukemia. 2017 Jul;31(7):1491-1501. doi: 10.1038/leu.2016.365. Epub 2016 Nov 30.
2017
DeepBlueR: large-scale epigenomic analysis in R.
Albrecht F,
List M,
Bock C,
Lengauer T.
Bioinformatics. 2017 Jul 1;33(13):2063-2064. doi: 10.1093/bioinformatics/btx099.
2017
It is a differentiation game: STAT5 in a new role.
Maurer B,
Farlik M,
Sexl V.
Cell Death Differ. 2017 Jun;24(6):953-954. doi: 10.1038/cdd.2017.71. Epub 2017 May 12. No abstract available.
2017
VCF.Filter: interactive prioritization of disease-linked genetic variants from sequencing data.
Müller H,
Jimenez-Heredia R,
Krolo A,
Hirschmugl T,
Dmytrus J,
Boztug K,
Bock C.
Filter: interactive prioritization of disease-linked genetic variants from sequencing data. Nucleic Acids Res. 2017 May 17. doi: 10.1093/nar/gkx425. [Epub ahead of print]
