Publications
2019
Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes.
Yi G,
Wierenga ATJ,
Petraglia F,
Narang P,
Janssen-Megens EM,
Mandoli A,
Merkel A,
Berentsen K,
Kim B,
Matarese F,
Singh AA,
Habibi E,
Prange KHM,
Mulder AB,
Jansen JH,
Clarke L,
Heath S,
van der Reijden BA,
Flicek P,
Yaspo ML,
Gut I, Bock C,
Schuringa JJ,
Altucci L,
Vellenga E,
Stunnenberg HG,
Martens JHA.
Cell Rep. 2019;26(4):1059–1069.e6. doi:10.1016/j.celrep.2018.12.098
2019
Genome-scale CRISPR screens are efficient in non-homologous end-joining deficient cells.
Ferreira da Silva J,
Salic S,
Wiedner M,
Datlinger P,
Essletzbichler P,
Hanzl A,
Superti-Furga G,
Bock C,
Winter G,
Loizou JI.
Sci Rep. 2019 Oct 31;9(1):15751. doi: 10.1038/s41598-019-52078-9.
2019
Guadecitabine Plus Ipilimumab in Unresectable Melanoma: The NIBIT-M4 Clinical Trial.
Di Giacomo AM,
Covre A,
Finotello F,
Rieder D,
Danielli R,
Sigalotti L,
Giannarelli D,
Petitprez F,
Lacroix L,
Valente M,
Cutaia O,
Fazio C,
Amato G,
Lazzeri A,
Monterisi S,
Miracco C,
Coral S,
Anichini A, Bock C,
Nemc A,
Oganesian A,
Lowder J,
Azab M,
Fridman WH,
Sautès-Fridman C,
Trajanoski Z,
Maio M.
Clin Cancer Res. 2019;25(24):7351–7362. doi:10.1158/1078-0432.CCR-19-1335
2019
Barthel FP, Johnson KC, Varn FS, et al.
Barthel FP,
Johnson KC,
Varn FS,
Moskalik AD,
Tanner G,
Kocakavuk E,
Anderson KJ,
Abiola O,
Aldape K,
Alfaro KD,
Alpar D,
Amin SB,
Ashley DM,
Bandopadhayay P,
Barnholtz-Sloan JS,
Beroukhim R, Bock C,
Brastianos PK,
Brat DJ,
Brodbelt AR,
Bruns AF,
Bulsara KR,
Chakrabarty A,
Chakravarti A,
Chuang JH,
Claus EB,
Cochran EJ,
Connelly J,
Costello JF,
Finocchiaro G,
Fletcher MN,
French PJ,
Gan HK,
Gilbert MR,
Gould PV,
Grimmer MR,
Iavarone A,
Ismail A,
Jenkinson MD,
Khasraw M,
Kim H,
Kouwenhoven MCM,
LaViolette PS,
Li M,
Lichter P,
Ligon KL,
Lowman AK,
Malta TM,
Mazor T,
McDonald KL,
Molinaro AM,
Nam DH,
Nayyar N,
Ng HK,
Ngan CY,
Niclou SP,
Niers JM,
Noushmehr H,
Noorbakhsh J,
Ormond DR,
Park CK,
Poisson LM,
Rabadan R,
Radlwimmer B,
Rao G,
Reifenberger G,
Sa JK,
Schuster M,
Shaw BL,
Short SC,
Smitt PAS,
Sloan AE,
Smits M,
Suzuki H,
Tabatabai G,
Van Meir EG,
Watts C,
Weller M,
Wesseling P,
Westerman BA,
Widhalm G,
Woehrer A,
Yung WKA,
Zadeh G,
Huse JT,
De Groot JF,
Stead LF,
Verhaak RGW; GLASS Consortium.
Longitudinal molecular trajectories of diffuse glioma in adults. Nature. 2019;576(7785):112–120. doi:10.1038/s41586-019-1775-1
2019
The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells.
Andersen L,
Gülich AF,
Alteneder M,
Preglej T,
Orola MJ,
Dhele N,
Stolz V,
Schebesta A,
Hamminger P,
Hladik A,
Floess S,
Krausgruber T,
Faux T,
Andrabi SBA,
Huehn J,
Knapp S,
Sparwasser T,
Bock C,
Laiho A,
Elo LL,
Rasool O,
Lahesmaa R,
Sakaguchi S,
Ellmeier W.
Cell Rep. 2019;29(13):4447–4459.e6. doi:10.1016/j.celrep.2019.11.089
2019
Colocalization analysesof genomic elements: approaches, recommendations and challenges.
Kanduri C,
Bock C,
Gundersen S,
Hovig E,
Sandve GK.
Bioinformatics. 2019 May 1;35(9):1615-1624. doi: 10.1093/bioinformatics/bty835. PubMed PMID:30307532;
2019
Integrative Proteomic Profiling RevealsPRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency.
van Mierlo G,
Dirks RAM,
De Clerck L,
Brinkman AB,
Huth M,
Kloet SL,
Saksouk N,
Kroeze LI,
Willems S,
Farlik M,
Bock C,
Jansen JH,
Deforce D,
Vermeulen M,Déjardin J,
Dhaenens M,
Marks H.
CellStem Cell. 2019 Jan 3;24(1):123-137.e8. doi: 10.1016/j.stem.2018.10.017. Epub2018 Nov 21.
2018
The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space.
Klughammer J,
Kiesel B,
Roetzer T,
Fortelny N,
Nemc A,
Nenning KH,
Furtner J,
Sheffield NC,
Datlinger P,
Peter N,
Nowosielski M,
Augustin M,
Mischkulnig M,
Ströbel T,
Alpar D,
Ergüner B,
Senekowitsch M,
Moser P,
Freyschlag CF,
Kerschbaumer J,
Thomé C,
Grams AE,
Stockhammer G,
Kitzwoegerer M,
Oberndorfer S,
Marhold F,
Weis S,
Trenkler J,
Buchroithner J,
Pichler J,
Haybaeck J,
Krassnig S,
Mahdy Ali K,
von Campe G,
Payer F,
Sherif C,
Preiser J,
Hauser T,
Winkler PA,
Kleindienst W,
Würtz F,
Brandner-Kokalj T,
Stultschnig M,
Schweiger S,
Dieckmann K,
Preusser M,
Langs G,
Baumann B,
Knosp E,
Widhalm G,
Marosi C,
Hainfellner JA,
Woehrer A,
Bock C.
Nat Med. 2018 Oct;24(10):1611-1624. doi: 10.1038/s41591-018-0156-x. Epub 2018 Aug 27.
2018
Colocalization analyses of genomic elements: approaches, recommendations and challenges.
Kanduri C,
Bock C,
Gundersen S,
Hovig E,
Sandve GK.
Bioinformatics. 2018 Oct 11. doi: 10.1093/bioinformatics/bty835. [Epub ahead of print]
2018
An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion.
Baumgartner C,
Toifl S,
Farlik M,
Halbritter F,
Scheicher R,
Fischer I,
Sexl V,
Bock C,
Baccarini M.
Cell Stem Cell. 2018 Jun 1;22(6):879-892.e6. doi: 10.1016/j.stem.2018.05.003. Epub 2018 May 24.
