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New CeMM Principal Investigator André Rendeiro


New CeMM Principal Investigator André Rendeiro (© Laura Alvarez / CeMM).

On 1 June 2022, André Rendeiro joins CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, as new Principal Investigator. André Rendeiro will employ computational approaches to understand human aging from a molecular, cellular and tissue level to the individual and population scale. His group will contribute to expanding CeMM’s expertise in the field of spatial and computational biology.

André Rendeiro studied Cell and Molecular Biology in Portugal, Austria and Norway. He earned his PhD at CeMM in the group of Principal Investigator Christoph Bock, where he developed methods for high-throughput cellular profiling and perturbation at single-cell resolution, applying them to leukemia. After his PhD, he joined the  Institute for Precision Medicine and the Institute for Computational Biomedicine at Weill Cornell Medicine in New York. There in the laboratory of Olivier Elemento, he developed computational methods for the analysis of highly-multiplexed imaging that incorporate expression, morphology, micro-anatomy, and clinical covariates. He led the first tissue-level, single-cell resolution maps of lung pathology during COVID-19, and also contributed to the study of cancer, lung development and chronic disease, and COVID-19 immunology. 

André Rendeiro’s group at CeMM will study how cells interact to generate complex physiology in the human body, and how this changes over the lifespan of individuals and give rise to disease. To accomplish this goal, they will develop and employ computational methods for the analysis of spatial data, its integration with various modalities of molecular data such as transcriptomics, proteomics, metabolomics, and importantly, clinical data of individuals along their lifespan. The group aims to establish a link between the molecular activity of cells, the emergence of higher-order patterns of tissue organization, and the onset of disease.

This new addition reinforces CeMM’s interdisciplinary nature and commitment to advancing the understanding of human diseases through basic and biomedical research. CeMM gladly welcomes André into the institute, and looks forward to his scientific breakthroughs and innovative research work in tissue architecture and the study of human aging and pathology!