Compound screening with cell viability read-out using CellTiterGlo
Compound screening with microscopy read-out (live-cell reporters, immunofluorescence, or other staining protocols)
Other biochemical or cell-based assays with luminescence, absorbance, fluorescence intensity, fluorescence polarization or AlphaScreen technology read-out (eg HiBiT, NanoLuc reporters, AlphaScreen, AlphaLISA, Resazurine, and others)
Direct-to-biology (D2B) miniaturized high-throughput chemical synthesis and product testing
Compound spotting to assay plates as stand-alone service
Access to our high-throughput equipment to facilitate miniaturization and/or automation of experimentation. Standard protocols are implemented for the accessory equipment (dispenser, washer, liquid handler, pipetting robot) which can be adapted to project-specific needs.
Variety of well-established standard protocols and pipelines for computational pre-screen preparation (picklist preparation, compound management) and basic data analysis (Z’ score, POC, AUC, bliss scores), as well as more sophisticated analysis of e.g. image-based screens available.
Cell culture support
