Selected Publications
enabled by the Chemical Screening Facility
© Klaus Pichler / CeMM
- Scholes, N.S. et al. Inhibitors supercharge kinase turnover through native proteolytic circuits. Nature 649, 1032–1041 (2026). DOI: 10.1038/s41586-025-09763-9
- Nguyen, T.A., Lin, J.G., Marques, A.M.C. et al. A non-enzymatic role of Nudix hydrolase 5 in repressing purine de novo synthesis. Science 390, 1143-1150 (2025). DOI: 10.1126/science.adv4257
- Reicher, A. et al. Pooled multicolour tagging for visualizing subcellular protein dynamics. Nat Cell Biol 26, 745–756 (2024). DOI: 10.1038/s41556-024-01407-w
- Knapp K. et al. Combination of compound screening with an animal model identifies pentamidine to prevent Chlamydia trachomatis infection. Cell Rep Med. 5, 7, 101643 (2024). DOI: 10.1016/j.xcrm.2024.101643
- Enders, L. et al. Pharmacological perturbation of the phase-separating protein SMNDC1. Nat Commun 14, 4504 (2023). DOI: 10.1038/s41467-023-40124-0
- Dvorak V. et al., Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors. Cell Chem Biol. 30, 953–964 (2023). DOI: 10.1016/j.chembiol.2023.06.029
- Ng A., Offensperger F., Cisneros J.A. et al. Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling. ACS Chem. Biol., 18, 12, 2464–2473 (2023). DOI: 10.1021/acschembio.3c00598
- Licciardello, M. et al. A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor. Nat Chem Biol 13, 771–778 (2017). DOI: 10.1038/nchembio.2382
