Publications
2023
PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing
Domagoj Cikes,
Kareem Elsayad,
Erdinc Sezgin,
Erika Koitai,
Ferenc Torma,
Michael Orthofer,
Rebecca Yarwood,
Leonhard X Heinz,
Vitaly Sedlyarov,
Nasser Darwish Miranda,
Adrian Taylor,
Sophie Grapentine,
Fathiya Al-Murshedi,
Anne Abot,
Adelheid Weidinger,
Candice Kutchukian,
Colline Sanchez,
Shane J F Cronin,
Maria Novatchkova,
Anoop Kavirayani,
Thomas Schuetz,
Bernhard Haubner,
Lisa Haas,
Astrid Hagelkruys,
Suzanne Jackowski,
Andrey V Kozlov,
Vincent Jacquemond,
Claude Knauf,
Giulio Superti-Furga,
Eric Rullman,
Thomas Gustafsson,
John McDermot,
Martin Lowe,
Zsolt Radak,
Jeffrey S Chamberlain,
Marica Bakovic,
Siddharth Banka,
Josef M Penninger.
Nat Metab. 2023 Mar;5(3):495-515. doi: 10.1038/s42255-023-00766-2. Epub 2023 Mar 20.
2023
A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery
Patrick Essletzbichler,
Vitaly Sedlyarov,
Fabian Frommelt,
Didier Soulat,
Leonhard X Heinz,
Adrijana Stefanovic,
Benedikt Neumayer,
Giulio Superti-Furga.
Life Sci Alliance. 2023 Feb 1;6(4):e202201715. doi: 10.26508/lsa.202201715. Print 2023 Apr.
2022
Functional characterization of SLC39 family members ZIP5 and ZIP10 in overexpressing HEK293 cells reveals selective copper transport activity
Marcello Polesel,
Alvaro Ingles-Prieto,
Eirini Christodoulaki,
Evandro Ferrada,
Cédric Doucerain,
Patrick Altermatt,
Michelle Knecht,
Michael Kuhn,
Anna-Lena Steck,
Maria Wilhelm,
Vania Manolova.
Biometals. 2023 Feb;36(1):227-237. doi: 10.1007/s10534-022-00474-6. Epub 2022 Dec 1.
2022
A structure and evolutionary-based classification of solute carriers
Evandro Ferrada,
Giulio Superti-Furga.
iScience. 2022 Sep 8;25(10):105096. doi: 10.1016/j.isci.2022.105096. eCollection 2022 Oct 21.
2022
Deep Morphology Learning Enhances Ex Vivo Drug Profiling-Based Precision Medicine
Tim Heinemann,
Christoph Kornauth,
Yannik Severin,
Gregory I Vladimer,
Tea Pemovska,
Emir Hadzijusufovic,
Hermine Agis,
Maria-Theresa Krauth,
Wolfgang R Sperr,
Peter Valent,
Ulrich Jäger,
Ingrid Simonitsch-Klupp,
Giulio Superti-Furga,
Philipp B Staber,
Berend Snijder.
Blood Cancer Discov. 2022 Nov 2;3(6):502-515. doi: 10.1158/2643-3230.BCD-21-0219.
2022
Gain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictions
Manuele Rebsamen,
Enrico Girardi,
Vitaly Sedlyarov,
Stefania Scorzoni,
Konstantinos Papakostas,
Manuela Vollert,
Justyna Konecka,
Bettina Guertl,
Kristaps Klavins,
Tabea Wiedmer,
Giulio Superti-Furga.
Life Sci Alliance. 2022 Sep 16;5(11):e202201404. doi: 10.26508/lsa.202201404. Print 2022 Nov.
2022
Accelerating SLC Transporter Research: Streamlining Knowledge and Validated Tools
Tabea Wiedmer,
Alvaro Ingles-Prieto,
Ulrich Goldmann,
Claire M Steppan,
Giulio Superti-Furga,
RESOLUTE, REsolution consortia.
Clin Pharmacol Ther. 2022 Sep;112(3):439-442. doi: 10.1002/cpt.2639. Epub 2022 Aug 8.
2022
Impedance-Based Phenotypic Readout of Transporter Function: A Case for Glutamate Transporters
Hubert J Sijben,
Laura Dall' Acqua,
Rongfang Liu,
Abigail Jarret,
Eirini Christodoulaki,
Svenja Onstein,
Gernot Wolf,
Simone J Verburgt,
Sylvia E Le Dévédec,
Tabea Wiedmer,
Giulio Superti-Furga,
Adriaan P IJzerman,
Laura H Heitman.
Front Pharmacol. 2022 May 23;13:872335. doi: 10.3389/fphar.2022.872335. eCollection 2022.
2022
Targeting solute carriers to modulate receptor-ligand interactions
Hubert J Sijben,
Giulio Superti-Furga,
Adriaan P IJzerman,
Laura H Heitman.
Trends Pharmacol Sci. 2022 May;43(5):358-361. doi: 10.1016/j.tips.2022.02.004. Epub 2022 Feb 26.
2021
Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation.
Tabata K,
Prasad V,
Paul D,
Lee JY,
Pham MT,
Twu WI,
Neufeldt CJ,
Cortese M,
Cerikan B,
Stahl Y,
Joecks S,
Tran CS,
Lüchtenborg C,
V'kovski P,
Hörmann K,
Müller AC,
Zitzmann C,
Haselmann U,
Beneke J,
Kaderali L,
Erfle H,
Thiel V,
Lohmann V,
Superti-Furga G,
Brügger B,
Bartenschlager R.
Nat Commun. 2021 Dec 14;12(1):7276. doi: 10.1038/s41467-021-27511-1.
