Publications
2024
Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily
Daniela Digles,
Alvaro Ingles-Prieto,
Vojtech Dvorak,
Tamara A M Mocking,
Ulrich Goldmann,
Andrea Garofoli,
Evert J Homan,
Alberto Di Silvio,
Lucia Azzollini,
Francesca Sassone,
Mario Fogazza,
Felix Bärenz,
Antje Pommereau,
Yasmin Zuschlag,
Jasper F Ooms,
Jeppe Tranberg-Jensen,
Jesper S Hansen,
Josefina Stanka,
Hubert J Sijben,
Helena Batoulis,
Eckhard Bender,
Riccardo Martini,
Adriaan P IJzerman,
David B Sauer,
Laura H Heitman,
Vania Manolova,
Juergen Reinhardt,
Alexander Ehrmann,
Philipp Leippe,
Gerhard F Ecker,
Kilian V M Huber,
Thomas Licher,
Lia Scarabottolo,
Tabea Wiedmer,
Giulio Superti-Furga.
Front Pharmacol. 2024 Jul 9;15:1401599. doi: 10.3389/fphar.2024.1401599. eCollection 2024.
2024
Correction: Functional characterization of SLC39 family members ZIP5 and ZIP10 in overexpressing HEK293 cells reveals selective copper transport activity
Marcello Polesel,
Alvaro Ingles-Prieto,
Eirini Christodoulaki,
Evandro Ferrada,
Cédric Doucerain,
Patrick Altermatt,
Michelle Knecht,
Michael Kuhn,
Anna-Lena Steck,
Maria Wilhelm,
Vania Manolova.
Biometals. 2024 Aug;37(4):1037-1038. doi: 10.1007/s10534-024-00615-z.
2024
Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP
Marko Cigler,
Hana Imrichova,
Fabian Frommelt,
Lucie Caramelle,
Laura Depta,
Andrea Rukavina,
Chrysanthi Kagiou,
J Thomas Hannich,
Cristina Mayor-Ruiz,
Giulio Superti-Furga,
Sonja Sievers,
Alison Forrester,
Luca Laraia,
Herbert Waldmann,
Georg E Winter.
Nat Chem Biol. 2025 Feb;21(2):193-202. doi: 10.1038/s41589-024-01614-4. Epub 2024 Jun 21.
2024
Protein Binder Toolbox for Studies of Solute Carrier Transporters
Zuzana Gelová,
Alvaro Ingles-Prieto,
Tina Bohstedt,
Fabian Frommelt,
Gamma Chi,
Yung-Ning Chang,
Julio Garcia,
Gernot Wolf,
Lucia Azzollini,
Sara Tremolada,
Andreea Scacioc,
Jesper S Hansen,
Iciar Serrano,
Aida Droce,
Jenifer Cuesta Bernal,
Nicola A Burgess-Brown,
Elisabeth P Carpenter,
Katharina L Dürr,
Peter Kristensen,
Eric R Geertsma,
Saša Štefanić,
Lia Scarabottolo,
Tabea Wiedmer,
Vera Puetter,
David B Sauer,
Giulio Superti-Furga.
J Mol Biol. 2024 Aug 15;436(16):168665. doi: 10.1016/j.jmb.2024.168665. Epub 2024 Jun 13.
2024
Development of a live cell assay for the zinc transporter ZnT8
Lucia Azzollini,
Dolores Del Prete,
Gernot Wolf,
Christoph Klimek,
Mattia Saggioro,
Fernanda Ricci,
Eirini Christodoulaki,
Tabea Wiedmer,
Alvaro Ingles-Prieto,
Giulio Superti-Furga,
Lia Scarabottolo.
SLAS Discov. 2024 Jul;29(5):100166. doi: 10.1016/j.slasd.2024.100166. Epub 2024 Jun 5.
2024
AspSnFR: A genetically encoded biosensor for real-time monitoring of aspartate in live cells
Lars Hellweg,
Martin Pfeifer,
Miroslaw Tarnawski,
Shao Thing-Teoh,
Lena Chang,
Andrea Bergner,
Jana Kress,
Julien Hiblot,
Tabea Wiedmer,
Giulio Superti-Furga,
Jürgen Reinhardt,
Kai Johnsson,
Philipp Leippe.
Cell Chem Biol. 2024 Aug 15;31(8):1529-1541.e12. doi: 10.1016/j.chembiol.2024.05.002. Epub 2024 May 27.
2024
Image-based quantification of mitochondrial iron uptake via Mitoferrin-2
Marcello Polesel,
Mattheus H E Wildschut,
Cédric Doucerain,
Michael Kuhn,
Anna Flace,
Leandro Sá Zanetti,
Anna-Lena Steck,
Maria Wilhelm,
Alvaro Ingles-Prieto,
Tabea Wiedmer,
Giulio Superti-Furga,
Vania Manolova,
Franz Dürrenberger.
Mitochondrion. 2024 Sep;78:101889. doi: 10.1016/j.mito.2024.101889. Epub 2024 Apr 30.
2024
Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells
Fabian Offensperger,
Gary Tin,
Miquel Duran-Frigola,
Elisa Hahn,
Sarah Dobner,
Christopher W Am Ende,
Joseph W Strohbach,
Andrea Rukavina,
Vincenth Brennsteiner,
Kevin Ogilvie,
Nara Marella,
Katharina Kladnik,
Rodolfo Ciuffa,
Jaimeen D Majmudar,
S Denise Field,
Ariel Bensimon,
Luca Ferrari,
Evandro Ferrada,
Amanda Ng,
Zhechun Zhang,
Gianluca Degliesposti,
Andras Boeszoermenyi,
Sascha Martens,
Robert Stanton,
André C Müller,
J Thomas Hannich,
David Hepworth,
Giulio Superti-Furga,
Stefan Kubicek,
Monica Schenone,
Georg E Winter.
Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
2024
ProteoMutaMetrics: machine learning approaches for solute carrier family 6 mutation pathogenicity prediction
Jiahui Huang,
Tanja Osthushenrich,
Aidan MacNamara,
Anders Mälarstig,
Silvia Brocchetti,
Samuel Bradberry,
Lia Scarabottolo,
Evandro Ferrada,
Sergey Sosnin,
Daniela Digles,
Giulio Superti-Furga,
Gerhard F Ecker.
RSC Adv. 2024 Apr 22;14(19):13083-13094. doi: 10.1039/d4ra00748d. eCollection 2024 Apr 22.
2024
EU-LIFE charter of independent life science research institutes
Giulio Superti-Furga,
Marta Agostinho,
Jo Bury,
Simon Cook,
Christine Durinx,
Anita Ender,
Henri van Luenen,
Anders H Lund,
René H Medema,
Marta Miączyńska,
Dorthe Nickel,
Pier Giuseppe Pelicci,
Alain Puisieux,
Samuli Ripatti,
Maike Sander,
Dirk Schubeler,
Luis Serrano,
Thomas Sommer,
Katrine Sonne-Hansen,
Pavel Tomančák,
Joan Vives,
John Vontas,
Mónica Bettencourt-Dias.
FEBS Lett. 2024 Apr;598(7):719-724. doi: 10.1002/1873-3468.14855. Epub 2024 Mar 21.
