Publications
2022
Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes
Denis Seyres,
Alessandra Cabassi,
John J Lambourne,
Frances Burden,
Samantha Farrow,
Harriet McKinney,
Joana Batista,
Carly Kempster,
Maik Pietzner,
Oliver Slingsby,
Thong Huy Cao,
Paulene A Quinn,
Luca Stefanucci,
Matthew C Sims,
Karola Rehnstrom,
Claire L Adams,
Amy Frary,
Bekir Ergüener,
Roman Kreuzhuber,
Gabriele Mocciaro,
Simona D'Amore,
Albert Koulman,
Luigi Grassi,
Julian L Griffin,
Leong Loke Ng,
Adrian Park,
David B Savage,
Claudia Langenberg,
Christoph Bock,
Kate Downes,
Nicholas J Wareham,
Michael Allison,
Michele Vacca,
Paul D W Kirk,
Mattia Frontini.
Clin Epigenetics. 2022 Mar 12;14(1):39. doi: 10.1186/s13148-022-01257-z.
2022
Rapid neutrophil mobilisation by VCAM-1+ endothelial extracellular vesicles
Naveed Akbar,
Adam T Braithwaite,
Emma M Corr,
Graeme J Koelwyn,
Coen van Solingen,
Clément Cochain,
Antoine-Emmanuel Saliba,
Alastair Corbin,
Daniela Pezzolla,
Malene Møller Jørgensen,
Rikke Bæk,
Laurienne Edgar,
Carla De Villiers,
Mala Gunadasa-Rohling,
Abhirup Banerjee,
Daan Paget,
Charlotte Lee,
Eleanor Hogg,
Adam Costin,
Raman Dhaliwal,
Errin Johnson,
Thomas Krausgruber,
Joey Riepsaame,
Genevieve E Melling,
Mayooran Shanmuganathan,
Oxford Acute Myocardial Infarction Study (OxAMI),
Christoph Bock,
David R F Carter,
Keith M Channon,
Paul R Riley,
Irina A Udalova,
Kathryn J Moore,
Daniel Anthony,
Robin P Choudhury.
Cardiovasc Res. 2022 Feb 4:cvac012. doi: 10.1093/cvr/cvac012. Online ahead of print.
2021
Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease.
Molteni R,
Biavasco R,
Stefanoni D,
Nemkov T,
Domínguez-Andrés J,
Arts RJ,
Merelli I,
Mazza D,
Zambrano S,
Panigada M,
Cantoni E,
Tengesdal IW,
Maksud P,
Piras F,
Cesana D,
Cassina L,
Distefano G,
Loffreda A,
Gnani D,
De Luca G,
Tomelleri A,
Campochiaro C,
Joosten LAB,
Dinarello CA,
Kajaste-Rudnitski A,
Haroche J,
Cardaci S,
Cenci S,
Dagna L,
Doglioni C,
Ferrarini M,
Ferrero E,
Boletta A,
D'Alessandro A,
Montini E,
Netea MG,
Cavalli G.
Blood. 2021 Oct 28;138(17):1554-1569. doi: 10.1182/blood.2020009594.
2021
Characterization of cephalic and non-cephalic sensory cell types provides insight into joint photo- and mechanoreceptor evolution.
Revilla-I-Domingo R,
Rajan VBV,
Waldherr M,
Prohaczka G,
Musset H,
Orel L,
Gerrard E,
Smolka M,
Stockinger A,
Farlik M,
Lucas RJ,
Raible F,
Tessmar-Raible K.
Elife. 2021 Aug 5;10:e66144. doi: 10.7554/eLife.66144.
2021
An inhibitor-mediated beta-cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation.
Casteels T,
Zhang Y,
Frogne T,
Sturtzel C,
Lardeau CH,
Sen I,
Liu X,
Hong S,
Pauler FM,
Penz T,
Brandstetter M,
Barbieux C,
Berishvili E,
Heuser T,
Bock C,
Riedel CG,
Meyer D,
Distel M,
Hecksher-Sørensen J,
Li J,
Kubicek S.
Mol Metab. 2021 Dec;54:101329. doi: 10.1016/j.molmet.2021.101329. Epub 2021 Aug 25.
2021
High-throughput drug screening identifies the ATR-CHK1 pathway as a therapeutic vulnerability of CALR mutated hematopoietic cells.
Jia R,
Kutzner L,
Koren A,
Runggatscher K,
Májek P,
Müller AC,
Schuster M,
Bock C,
Loizou JI,
Kubicek S,
Kralovics R.
Blood Cancer J. 2021 Jul 31;11(7):137. doi: 10.1038/s41408-021-00531-2.
2021
The Immunological Factors Predisposing to Severe Covid-19 Are Already Present in Healthy Elderly and Men.
Kilic G,
Bulut O,
Jaeger M,
Ter Horst R,
Koeken VACM,
Moorlag SJCFM,
Mourits VP,
de Bree C,
Domínguez-Andrés J,
Joosten LAB,
Netea MG.
Front Immunol. 2021 Aug 9;12:720090. doi: 10.3389/fimmu.2021.720090. eCollection 2021.
2021
Human resident memory T cells exit the skin and mediate systemic Th2-driven inflammation.
Strobl J,
Gail LM,
Kleissl L,
Pandey RV,
Smejkal V,
Huber J,
Puxkandl V,
Unterluggauer L,
Dingelmaier-Hovorka R,
Atzmüller D,
Krausgruber T,
Bock C,
Wohlfarth P,
Rabitsch W,
Stary G.
J Exp Med. 2021 Nov 1;218(11):e20210417. doi: 10.1084/jem.20210417. Epub 2021 Oct 13.
2021
Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3.
Santini L,
Halbritter F,
Titz-Teixeira F,
Suzuki T,
Asami M,
Ma X,
Ramesmayer J,
Lackner A,
Warr N,
Pauler F,
Hippenmeyer S,
Laue E,
Farlik M,
Bock C,
Beyer A,
Perry ACF,
Leeb M.
Nat Commun. 2021 Jun 21;12(1):3804. doi: 10.1038/s41467-021-23510-4.
2021
A STAT5B-CD9 axis determines self-renewal in hematopoietic and leukemic stem cells.
Kollmann S,
Grausenburger R,
Klampfl T,
Prchal-Murphy M,
Bastl K,
Pisa H,
Knab VM,
Brandstoetter T,
Doma E,
Sperr WR,
Lagger S,
Farlik M,
Moriggl R,
Valent P,
Halbritter F,
Kollmann K,
Heller G,
Maurer B,
Sexl V.
Blood. 2021 Dec 9;138(23):2347-2359. doi: 10.1182/blood.2021010980.
