Publications
2023
In vivo CRISPR/Cas9 screening identifies Pbrm1 as a regulator of myeloid leukemia development in mice
Bin E Li,
Grace Y Li,
Wenqing Cai,
Qian Zhu,
Davide Seruggia,
Yuko Fujiwara,
Christopher R Vakoc,
Stuart H Orkin.
Blood Adv. 2023 Sep 26;7(18):5281-5293. doi: 10.1182/bloodadvances.2022009455.
2022
Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells
Stuti Mehta,
Altantsetseg Buyanbat,
Yan Kai,
Ozge Karayel,
Seth Raphael Goldman,
Davide Seruggia,
Kevin Zhang,
Yuko Fujiwara,
Katherine A Donovan,
Qian Zhu,
Huan Yang,
Behnam Nabet,
Nathanael S Gray,
Matthias Mann,
Eric S Fischer,
Karen Adelman,
Stuart H Orkin.
Cell Chem Biol. 2022 Aug 18;29(8):1273-1287.e8. doi: 10.1016/j.chembiol.2022.06.007. Epub 2022 Jul 14.
2021
Germline biallelic mutation affecting the transcription factor Helios causes pleiotropic defects of immunity.
Shahin T,
Kuehn HS,
Shoeb MR,
Gawriyski L,
Giuliani S,
Repiscak P,
Hoeger B,
Yüce Petronczki Ö,
Bal SK,
Zoghi S,
Dmytrus J,
Seruggia D,
Castanon I,
Rezaei N,
Varjosalo M,
Halbritter F,
Rosenzweig SD,
Boztug K.
Sci Immunol. 2021 Nov 26;6(65):eabe3981. doi: 10.1126/sciimmunol.abe3981. Epub 2021 Nov 26.
