Publications
2020
P53 clears aneuploid cells by entosis.
Rizzotto D,
Villunger A.
Cell Death Differ. 2021 Feb;28(2):818-820. doi: 10.1038/s41418-020-00659-x. Epub 2020 Nov 4.
2020
PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis.
Sladky VC,
Knapp K,
Szabo TG,
Braun VZ,
Bongiovanni L,
van den Bos H,
Spierings DC,
Westendorp B,
Curinha A,
Stojakovic T,
Scharnagl H,
Timelthaler G,
Tsuchia K,
Pinter M,
Semmler G,
Foijer F,
de Bruin A,
Reiberger T,
Rohr-Udilova N,
Villunger A.
EMBO Rep. 2020 Dec 3;21(12):e50893. doi: 10.15252/embr.202050893. Epub 2020 Nov 23.
2020
Centriolar distal appendages activate the centrosome-PIDDosome-p53 signalling axis via ANKRD26.
Burigotto M,
Mattivi A,
Migliorati D,
Magnani G,
Valentini C,
Roccuzzo M,
Offterdinger M,
Pizzato M,
Schmidt A,
Villunger A,
Maffini S,
Fava LL.
EMBO J. 2021 Feb 15;40(4):e104844. doi: 10.15252/embj.2020104844. Epub 2020 Dec 22.
2020
E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration.
Sladky VC,
Knapp K,
Soratroi C,
Heppke J,
Eichin F,
Rocamora-Reverte L,
Szabo TG,
Bongiovanni L,
Westendorp B,
Moreno E,
van Liere EA,
Bakker B,
Spierings DCJ,
Wardenaar R,
Pereyra D,
Starlinger P,
Schultze S,
Trauner M,
Stojakovic T,
Scharnagl H,
Fava LL,
Foijer F,
de Bruin A,
Villunger A.
Dev Cell. 2020 Feb 10;52(3):335-349.e7. doi: 10.1016/j.devcel.2019.12.016. Epub 2020 Jan 23.
2019
BIRC3 Expression Predicts CLL Progression and Defines Treatment Sensitivity via Enhanced NF-κB Nuclear Translocation.
Asslaber D,
Wacht N,
Leisch M,
Qi Y,
Maeding N,
Hufnagl C,
Jansko B,
Zaborsky N,
Villunger A,
Hartmann TN,
Greil R,
Egle A.
Clin Cancer Res. 2019 Mar 15;25(6):1901-1912. doi:10.1158/1078-0432.CCR-18-1548. Epub 2018 Nov 28.
2019
Glucocorticoid Receptor-Deficient Foxp3(+) Regulatory T Cells Fail to Control Experimental Inflammatory Bowel Disease.
Rocamora-Reverte L,
Tuzlak S,
von Raffay L,
Tisch M,
Fiegl H,
Drach M,Reichardt HM,
Villunger A,
Tischner D,
Wiegers GJ.
Front Immunol. 2019 Mar 18;10:472. doi:10.3389/fimmu.2019.00472. eCollection 2019.
2019
TET enzymes control antibody production and shape the mutational landscape in germinal centre B cells.
Schoeler K,
Aufschnaiter A,
Messner S,
Derudder E,
Herzog S,
Villunger A,Rajewsky K,
Labi V.
FEBS J. 2019 May 23. doi:10.1111/febs.14934. [Epub ahead of print]
2019
CHK1 dosage in germinal center B cells controls humoral immunity.
Schoeler K,
Jakic B,
Heppke J,
Soratroi C,
Aufschnaiter A,
Hermann-Kleiter N,Villunger A,
Labi V.
Cell Death Differ. 2019 Mar 20. doi: 10.1038/s41418-019-0318-5. [Epubahead of print]
2019
Cell-Cycle Cross Talk with Caspases and Their Substrates.
Connolly P,
Garcia-Carpio I,
Villunger A.
Cold Spring Harb Perspect Biol. 2019 Nov 14. pii: a036475. doi: 10.1101/cshperspect.a036475.
2019
Checkpoint kinase 1 is essential for fetal and adult hematopoiesis.
Schuler F,
Afreen S,
Manzl C,
Häcker G,
Erlacher M,
Villunger A.
EMBO Rep. 2019 Aug;20(8):e47026. doi: 10.15252/embr.201847026. Epub 2019 Jun 17.
