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Publications

2017

A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor.

Licciardello MP, Ringler A, Markt P, Klepsch F, Lardeau CH, Sdelci S, Schirghuber E, Müller AC, Caldera M, Wagner A, Herzog R, Penz T, Schuster M, Boidol B, Dürnberger G, Folkvaljon Y, Stattin P, Ivanov V, Colinge J, Bock C, Kratochwill K, Menche J, Bennett KL, Kubicek S.
Nat Chem Biol. 2017 Jul;13(7):771-778. doi: 10.1038/nchembio.2382. Epub 2017 May 22.
2017

Network medicine: a new paradigm for cardiovascular disease research and beyond.

Menche J.
Cardiovasc Res. 2017 Aug 1;113(10):e29-e30. doi: 10.1093/cvr/cvx129. No abstract available.
2017

Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia.

Moder M, Velimezi G, Owusu M, Mazouzi A, Wiedner M, Ferreira da Silva J, Robinson-Garcia L, Schischlik F, Slavkovsky R, Kralovics R, Schuster M, Bock C, Ideker T, Jackson SP, Menche J, Loizou JI.
 Nat Commun. 2017 Nov 1;8(1):1238. doi: 10.1038/s41467-017-01439-x.
2017

Integrating personalized gene expression profiles into predictive disease-associated gene pool.

J Menche*, E Guney*, A.
npj Systems Biology & Applications 3:10; 2017. doi:10.1038/s41540-017-0009-0.
2017

Integrating personalized gene expression profiles into predictive disease-associated gene pool.

J Menche*, E Guney*, A.
npj Systems Biology & Applications 3:10; 2017. doi:10.1038/s41540-017-0009-0.
2016

Tissue Specificity of Human Disease Module .

M Kitsak, A Sharma, J Menche, E Guney, SD Ghiassian, J Loscalzo, A-L Barabási, J Loscalzo.
Scientific Reports 6:35241; 2016. doi: 10.1038/srep35241.
2016

An inter-species protein–protein interaction network across vast evolutionary distance Molecular Systems Biology 12:865; 2016.

Q Zhong, S J Pevzner, T Hao, Y Wang, R Mosca, J Menche, M Taipale, M Tasan, C Fan, X Yang, P Haley, R R Murray, F Mer, F Gebreab, S Tam, A MacWilliams, A Dricot, P Reichert, B Santhanam, L Ghamsari, M A Calderwood, T Rolland, B Charloteaux, S Lindquist, A-L Barabási, D E Hill, P Aloy, M E Cusick, Y Xia, F P Roth & M Vidal.
doi: 10.15252/msb.20156484.
2016

Tissue Specificity of Human Disease Module.

Kitsak M, Sharma A, Menche J, Guney E, Ghiassian SD, Loscalzo J, Barabási AL.
Sci Rep. 2016 Oct 17;6:35241. doi: 10.1038/srep35241.
2016

Network-based in silico drug efficacy screening.

E Guney, J Menche, M Vidal, AL Barabási.
Nature Communications 7:10331, 2016. doi: 10.1038/ncomms10331.
2016

Endophenotype Network Models: Common Core of Complex Diseases.

SD Ghiassian, J Menche, DI Chasman, F Giulianini, R Wang, P Ricchiuto, M Aikawa, H Iwata, C Müller, T Zeller, A Sharma, P Wild, K Lackner, S Singh, PM Ridker, S Blankenberg, A-L Barabási, J Loscalzo.
Scientific Reports 6:27414; 2016. doi: 10.1038/srep27414.