Publications
2017
Repair of UV-Induced DNA Damage Independent of Nucleotide Excision Repair Is Masked by MUTYH.
Mazouzi A,
Battistini F,
Moser SC,
Ferreira da Silva J,
Wiedner M,
Owusu M,
Lardeau CH,
Ringler A,
Weil B,
Neesen J,
Orozco M,
Kubicek S,
Loizou JI.
Mol Cell. 2017 Nov 16;68(4):797-807.e7. doi: 10.1016/j.molcel.2017.10.021
2017
Cdk6 contributes to cytoskeletal stability in erythroid cells.
Uras IZ,
Scheicher RM,
Kollmann K,
Glösmann M,
Prchal-Murphy M,
Tigan AS,
Fux DA,
Altamura S,
Neves J,
Muckenthaler MU,
Bennett KL,
Kubicek S,
Hinds PW,
von Lindern M,
Sexl V.
Haematologica. 2017 Jun;102(6):995-1005. doi: 10.3324/haematol.2016.159947. Epub 2017 Mar 2.
2017
TKI rotation-induced persistent deep molecular response in multi-resistant blast crisis of Ph+ CML.
Valent P,
Herndlhofer S,
Schneeweiß M,
Boidol B,
Ringler A,
Kubicek S,
Gleixner KV,
Hoermann G,
Hadzijusufovic E,
Müllauer L,
Sperr WR,
Superti-Furga G,
Mannhalter C.
Oncotarget. 2017 Apr 4;8(14):23061-23072. doi: 10.18632/oncotarget.15481.
2017
Global survey of the immunomodulatory potential of common drugs.
Vladimer GI,
Snijder B,
Krall N,
Bigenzahn JW,
Huber KVM,
Lardeau CH,
Sanjiv K,
Ringler A,
Berglund UW,
Sabler M,
de la Fuente OL,
Knöbl P,
Kubicek S,
Helleday T,
Jäger U,
Superti-Furga G.
Nat Chem Biol. 2017 Jun;13(6):681-690. doi: 10.1038/nchembio.2360. Epub 2017 Apr 24.
2017
A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor.
Licciardello MP,
Ringler A,
Markt P,
Klepsch F,
Lardeau CH,
Sdelci S,
Schirghuber E,
Müller AC,
Caldera M,
Wagner A,
Herzog R,
Penz T,
Schuster M,
Boidol B,
Dürnberger G,
Folkvaljon Y,
Stattin P,
Ivanov V,
Colinge J,
Bock C,
Kratochwill K,
Menche J,
Bennett KL,
Kubicek S.
Nat Chem Biol. 2017 Jul;13(7):771-778. doi: 10.1038/nchembio.2382. Epub 2017 May 22.
2017
A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover.
Malenczyk K,
Girach F,
Szodorai E,
Storm P,
Segerstolpe Å,
Tortoriello G,
Schnell R,
Mulder J,
Romanov RA,
Borók E,
Piscitelli F,
Di Marzo V,
Szabó G,
Sandberg R,
Kubicek S,
Lubec G,
Hökfelt T,
Wagner L,
Groop L,
Harkany T.
EMBO J. 2017 Jul 14;36(14):2107-2125. doi: 10.15252/embj.201695347. Epub 2017 Jun 21.
2017
A histone-mimicking interdomain linker in a multidomain protein modulates multivalent histone binding.
Kostrhon S,
Kontaxis G,
Kaufmann T,
Schirghuber E,
Kubicek S,
Konrat R,
Slade D.
J Biol Chem. 2017 Oct 27;292(43):17643-17657. doi: 10.1074/jbc.M117.801464. Epub 2017 Sep 1.
2016
Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity, Cell 2017 Jan 12 (epub ahead of print 2016 Dec 1);168(1), 86-100.
Li J,
Casteels T,
Frogne T,
Ingvorsen C,
Honoré C,
Courtney M,
Huber KVM,
Schmitner N,
Kimmel RA,
Romanov RA,
Sturtzel C,
Lardeau CH,
Klughammer J,
Farlik M,
Sdelci S,
Vieira A,
Avolio F,
Briand F,
Baburin I,
Májek P,
Pauler FM,
Penz T,
Stukalov A,
Gridling M,
Parapatics K,
Barbieux C,
Berishvili E,
Spittler A,
Colinge J,
Bennett KL,
Hering S,
Sulpice T,
Bock C,
Distel M,
Harkany T,
Meyer D,
Superti-Furga G,
Collombat P,
Hecksher-Sørensen J,
and Kubicek S.
doi:10.1016/j.cell.2016.11.010. Abstract: http://www.cell.com/cell/abstract/S0092-8674(16)31531-8
2016
Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk.
Sdelci S,
Lardeau CH,
Tallant C,
Klepsch F,
Klaiber B,
Bennett J,
Rathert P,
Schuster M,
Penz T,
Fedorov O,
Superti-Furga G,
Bock C,
Zuber J,
Huber KV,
Knapp S,
Müller S,
Kubicek S.
Nat Chem Biol. 2016 May 9. doi: 10.1038/nchembio.2080.
2016
DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling.
Guryanova OA,
Shank K,
Spitzer B,
Luciani L,
Koche RP,
Garrett-Bakelman FE,
Ganzel C,
Durham BH,
Mohanty A,
Hoermann G,
Rivera SA,
Chramiec AG,
Pronier E,
Bastian L,
Keller MD,
Tovbin D,
Loizou E,
Weinstein AR,
Gonzalez AR,
Lieu YK,
Rowe JM,
Pastore F,
McKenney AS,
Krivtsov AV,
Sperr WR,
Cross JR,
Mason CE,
Tallman MS,
Arcila ME,
Abdel-Wahab O,
Armstrong SA,
Kubicek S,
Staber PB,
Gönen M,
Paietta EM,
Melnick AM,
Nimer SD,
Mukherjee S,
Levine RL.
Nat Med. 2016 Dec;22(12):1488-1495. doi: 10.1038/nm.4210.
