Publications
2020
Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK-driven lymphomagenesis.
Redl E,
Sheibani-Tezerji R,
Cardona CJ,
Hamminger P,
Timelthaler G,
Hassler MR,
Zrimšek M,
Lagger S,
Dillinger T,
Hofbauer L,
Draganić K,
Tiefenbacher A,
Kothmayer M,
Dietz CH,
Ramsahoye BH,
Kenner L,
Bock C,
Seiser C,
Ellmeier W,
Schweikert G,
Egger G.
Life Sci Alliance. 2020 Dec 11;4(2):e202000794. doi: 10.26508/lsa.202000794.
2020
STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway.
Swoboda A,
Soukup R,
Eckel O,
Kinslechner K,
Wingelhofer B,
Schörghofer D,
Sternberg C,
Pham HTT,
Vallianou M,
Horvath J,
Stoiber D,
Kenner L,
Larue L,
Poli V,
Beermann F,
Yokota T,
Kubicek S,
Krausgruber T,
Rendeiro AF,
Bock C,
Zenz R,
Kovacic B,
Aberger F,
Hengstschläger M,
Petzelbauer P,
Mikula M,
Moriggl R.
Oncogene. 2021 Feb;40(6):1091-1105. doi: 10.1038/s41388-020-01584-6.
2020
RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy.
Paolino M,
Koglgruber R,
Cronin SJF,
Uribesalgo I,
Rauscher E,
Harreiter J,
Schuster M,
Bancher-Todesca D,
Pranjic B,
Novatchkova M,
Fededa JP,
White AJ,
Sigl V,
Dekan S,
Penz T,
Bock C,
Kenner L,
Holländer GA,
Anderson G,
Kautzky-Willer A,
Penninger JM.
Nature. 2021 Jan;589(7842):442-447. doi: 10.1038/s41586-020-03071-0. Epub 2020 Dec 23.
2020
Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib response in CLL.
Rendeiro AF,
Krausgruber T,
Fortelny N,
Zhao F,
Penz T,
Farlik M,
Schuster LC,
Nemc A,
Tasnády S,
Réti M,
Mátrai Z,
Alpár D,
Bödör C,
Schmidl C,
Bock C.
Nat Commun. 2020 Jan 29;11(1):577. doi: 10.1038/s41467-019-14081-6.
2020
Structural cells are key regulators of organ-specific immune responses.
Krausgruber T,
Fortelny N,
Fife-Gernedl V,
Senekowitsch M,
Schuster LC,
Lercher A,
Nemc A,
Schmidl C,
Rendeiro AF,
Bergthaler A,
Bock C.
Nature. 2020 Jul;583(7815):296-302. doi: 10.1038/s41586-020-2424-4. Epub 2020 Jul 1.
2020
CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del(11q) CLL cells to dual BCR and PARP inhibition.
Quijada-Álamo M,
Hernández-Sánchez M,
Alonso-Pérez V,
Rodríguez-Vicente AE,
García-Tuñón I,
Martín-Izquierdo M,
Hernández-Sánchez JM,
Herrero AB,
Bastida JM,
San Segundo L,
Gruber M,
García JL,
Yin S,
Ten Hacken E,
Benito R,
Ordóñez JL,
Wu CJ,
Hernández-Rivas JM.
Leukemia. 2020 Jan 23. doi: 10.1038/s41375-020-0714-3. Epub ahead of print.
2020
Single-cell RNA-seq with spike-in cells enables accurate quantification of cell-specific drug effects in pancreatic islets.
Marquina-Sanchez B,
Fortelny N,
Farlik M,
Vieira A,
Collombat P,
Bock C,
Kubicek S.
Genome Biol. 2020 May 6;21(1):106. doi: 10.1186/s13059-020-02006-2.
2020
NCOR1 Orchestrates Transcriptional Landscapes and Effector Functions of CD4+ T Cells.
Hainberger D,
Stolz V,
Zhu C,
Schuster M,
Müller L,
Hamminger P,
Rica R,
Waltenberger D,
Alteneder M,
Krausgruber T,
Hladik A,
Knapp S,
Bock C,
Trauner M,
Farrar MA,
Ellmeier W.
Front Immunol. 2020 Apr 3;11:579. doi: 10.3389/fimmu.2020.00579.
2020
Publisher Correction: Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection.
Ulz P,
Perakis S,
Zhou Q,
Moser T,
Belic J,
Lazzeri I,
Wölfler A,
Zebisch A,
Gerger A,
Pristauz G,
Petru E,
White B,
Roberts CES,
John JS,
Schimek MG,
Geigl JB,
Bauernhofer T,
Sill H,
Bock C,
Heitzer E,
Speicher MR.
Nat Commun. 2020 Apr 20;11(1):1965. doi: 10.1038/s41467-020-15799-4. Erratum for: Nat Commun. 2019 Oct 11;10(1):4666.
2020
Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells.
Rosser EC,
Piper CJM,
Matei DE,
Blair PA,
Rendeiro AF,
Orford M,
Alber DG,
Krausgruber T,
Catalan D,
Klein N,
Manson JJ,
Drozdov I,
Bock C,
Wedderburn LR,
Eaton S,
Mauri C.
Cell Metab. 2020 Apr 7;31(4):837-851.e10. doi: 10.1016/j.cmet.2020.03.003. Epub 2020 Mar 25.
