2018
Pharmacologic inhibition of STAT5 in acute myeloid leukemia.
Wingelhofer B,
Maurer B,
Heyes EC,
Cumaraswamy AA,
Berger-Becvar A,
de Araujo ED,
Orlova A,
Freund P,
Ruge F,
Park J,
Tin G,
Ahmar S,
Lardeau CH,
Sadovnik I,
Bajusz D,
Keserű GM,
Grebien F,
Kubicek S,
Valent P,
Gunning PT,
Moriggl R.
Leukemia. 2018 May;32(5):1135-1146. doi: 10.1038/s41375-017-0005-9. Epub 2018 Feb 2.
2018
Ageing-associated DNA methylation dynamics are a molecular readout of lifespan variation among mammalian species.
Lowe R,
Barton C,
Jenkins CA,
Ernst C,
Forman O,
Fernandez-Twinn DS,
Bock C,
Rossiter SJ,
Faulkes CG,
Ozanne SE,
Walter L,
Odom DT,
Mellersh C,
Rakyan VK.
Genome Biol. 2018 Feb 16;19(1):22. doi: 10.1186/s13059-018-1397-1.
2018
Parental micronutrient deficiency distorts liver DNA methylation and expression of lipid genes associated with a fatty-liver-like phenotype in offspring.
Skjærven KH,
Jakt LM,
Fernandes JMO,
Dahl JA,
Adam AC,
Klughammer J,
Bock C,
Espe M.
Sci Rep. 2018 Feb 14;8(1):3055. doi: 10.1038/s41598-018-21211-5.
2018
Deletion of IRF8 (Interferon Regulatory Factor 8)-Dependent Dendritic Cells Abrogates Proatherogenic Adaptive Immunity.
Clément M,
Haddad Y,
Raffort J,
Lareyre F,
Newland SA,
Master L,
Harrison J,
Ozsvar-Kozma M,
Bruneval P,
Binder CJ,
Taleb S,
Mallat Z.
Circ Res. 2018 Mar 16;122(6):813-820. doi: 10.1161/CIRCRESAHA.118.312713. Epub 2018 Feb 7.
2018
Glioma Through the Looking GLASS: Molecular Evolution of Diffuse Gliomas and the Glioma Longitudinal AnalySiS Consortium.
Aldape K,
Amin SB,
Ashley DM,
Barnholtz-Sloan JS,
Bates AJ,
Beroukhim R,
Bock C,
Brat DJ,
Claus EB,
Costello JF,
de Groot JF,
Finocchiaro G,
French PJ,
Gan HK,
Griffith B,
Herold-Mende CC,
Horbinski C,
Iavarone A,
Kalkanis SN,
Karabatsou K,
Kim H,
Kouwenhoven MCM,
McDonald KL,
Miletic H,
Nam DH,
Ng HK,
Niclou SP,
Noushmehr H,
Ormond R,
Poisson LM,
Reifenberger G,
Roncaroli F,
Sa JK,
Sillevis Smitt PAE,
Smits M,
Souza CF,
Tabatabai G,
Van Meir EG,
Verhaak RGW,
Watts C,
Wesseling P,
Woehrer A,
Yung WKA,
Jungk C,
Hau AC,
van Dyck E,
Westerman BA,
Yin J,
Abiola O,
Zeps N,
Grimmond S,
Buckland M,
Khasraw M,
Sulman EP,
Muscat AM,
Stead L; GLASS Consortium.
Neuro Oncol. 2018 Feb 8. doi: 10.1093/neuonc/noy020. [Epub ahead of print]
2018
Human NF-κB1 Haploinsufficiency and Epstein-Barr Virus-Induced Disease-Molecular Mechanisms and Consequences.
Hoeger B,
Serwas NK,
Boztug K.
Front Immunol. 2018 Jan 18;8:1978. doi: 10.3389/fimmu.2017.01978. eCollection 2017. Review.
2018
Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage.
Perugorria MJ,
Esparza-Baquer A,
Oakley F,
Labiano I,
Korosec A,
Jais A,
Mann J,
Tiniakos D,
Santos-Laso A,
Arbelaiz A,
Gawish R,
Sampedro A,
Fontanellas A,
Hijona E,
Jimenez-Agüero R,
Esterbauer H,
Stoiber D,
Bujanda L,
Banales JM,
Knapp S,
Sharif O,
Mann DA.
Gut. 2018 Jan 27. pii: gutjnl-2017-314107. doi: 10.1136/gutjnl-2017-314107. [Epub ahead of print]
2018
Oxidized phospholipids stimulate production of stem cell factor via NRF2-dependent mechanisms.
Afonyushkin T,
Oskolkova OV,
Bochkov VN.
Angiogenesis. 2018 May;21(2):229-236. doi: 10.1007/s10456-017-9590-5. Epub 2018 Jan 12. PubMed PMID: 29330760; PubMed Central PMCID: PMC5878191.
2018
Mutations outside the N-terminal part of RBCK1 may cause polyglucosan body myopathy with immunological dysfunction: expanding the genotype-phenotype spectrum.
Krenn M,
Salzer E,
Simonitsch-Klupp I,
Rath J,
Wagner M,
Haack TB,
Strom TM,
Schänzer A,
Kilimann MW,
Schmidt RLJ,
Schmetterer KG,
Zimprich A,
Boztug K,
Hahn A,
Zimprich F.
J Neurol. 2018 Feb;265(2):394-401. doi: 10.1007/s00415-017-8710-x. Epub 2017 Dec 19.
2018
STAT5BN642H is a driver mutation for T cell neoplasia.
Pham HTT,
Maurer B,
Prchal-Murphy M,
Grausenburger R,
Grundschober E,
Javaheri T,
Nivarthi H,
Boersma A,
Kolbe T,
Elabd M,
Halbritter F,
Pencik J,
Kazemi Z,
Grebien F,
Hengstschläger M,
Kenner L,
Kubicek S,
Farlik M,
Bock C,
Valent P,
Müller M,
Rülicke T,
Sexl V,
Moriggl R.
J Clin Invest. 2018 Jan 2;128(1):387-401. doi: 10.1172/JCI94509. Epub 2017 Dec 4.
