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2021

P53 clears aneuploid cells by entosis.

Rizzotto D, Villunger A.
Cell Death Differ. 2021 Feb;28(2):818-820. doi: 10.1038/s41418-020-00659-x. Epub 2020 Nov 4.
2021

5-Arylidene-2-(4-hydroxyphenyl)aminothiazol-4(5H)-ones with selective inhibitory activity against some leukemia cell lines.

Subtelna I, Kryshchyshyn-Dylevych A, Jia R, Lelyukh M, Ringler A, Kubicek S, Zagrijtschuk O, Kralovics R, Lesyk R.
Arch Pharm (Weinheim). 2021 Apr;354(4):e2000342. doi: 10.1002/ardp.202000342. Epub 2020 Nov 25.
2021

Multimodality imaging beyond CLEM: Showcases of combined in-vivo preclinical imaging and ex-vivo microscopy to detect murine mural vascular lesions.

Keuenhof K, Heimel P, Zopf LM, Raigel M, Turyanskaya A, Kavirayani A, Reier S, Glösmann M, Schöfer C, Kralovics R, Streli C, Weninger WJ, Geyer SH, Slezak P, Macfelda K, Jäger R, Wanek T, Walter A.
Methods Cell Biol. 2021;162:389-415. doi: 10.1016/bs.mcb.2020.10.002. Epub 2020 Dec 2.
2021

Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK-driven lymphomagenesis.

Redl E, Sheibani-Tezerji R, Cardona CJ, Hamminger P, Timelthaler G, Hassler MR, Zrimšek M, Lagger S, Dillinger T, Hofbauer L, Draganić K, Tiefenbacher A, Kothmayer M, Dietz CH, Ramsahoye BH, Kenner L, Bock C, Seiser C, Ellmeier W, Schweikert G, Egger G.
Life Sci Alliance. 2020 Dec 11;4(2):e202000794. doi: 10.26508/lsa.202000794. Print 2021 Feb.
2021

STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway.

Swoboda A, Soukup R, Eckel O, Kinslechner K, Wingelhofer B, Schörghofer D, Sternberg C, Pham HTT, Vallianou M, Horvath J, Stoiber D, Kenner L, Larue L, Poli V, Beermann F, Yokota T, Kubicek S, Krausgruber T, Rendeiro AF, Bock C, Zenz R, Kovacic B, Aberger F, Hengstschläger M, Petzelbauer P, Mikula M, Moriggl R.
Oncogene. 2021 Feb;40(6):1091-1105. doi: 10.1038/s41388-020-01584-6. Epub 2020 Dec 15.
2021

E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes.

Sarbanes SL, Blomen VA, Lam E, Heissel S, Luna JM, Brummelkamp TR, Falck-Pedersen E, Hoffmann HH, Rice CM.
Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2015794118. doi: 10.1073/pnas.2015794118. Epub 2020 Dec 21.
2021

Centriolar distal appendages activate the centrosome-PIDDosome-p53 signalling axis via ANKRD26.

Burigotto M, Mattivi A, Migliorati D, Magnani G, Valentini C, Roccuzzo M, Offterdinger M, Pizzato M, Schmidt A, Villunger A, Maffini S, Fava LL.
EMBO J. 2021 Feb 15;40(4):e104844. doi: 10.15252/embj.2020104844. Epub 2020 Dec 22.
2021

RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy.

Paolino M, Koglgruber R, Cronin SJF, Uribesalgo I, Rauscher E, Harreiter J, Schuster M, Bancher-Todesca D, Pranjic B, Novatchkova M, Fededa JP, White AJ, Sigl V, Dekan S, Penz T, Bock C, Kenner L, Holländer GA, Anderson G, Kautzky-Willer A, Penninger JM.
Nature. 2021 Jan;589(7842):442-447. doi: 10.1038/s41586-020-03071-0. Epub 2020 Dec 23.
2021

The Organoid Cell Atlas.

Bock C, Boutros M, Camp JG, Clarke L, Clevers H, Knoblich JA, Liberali P, Regev A, Rios AC, Stegle O, Stunnenberg HG, Teichmann SA, Treutlein B, Vries RGJ; Human Cell Atlas ‘Biological Network’ Organoids.
Nat Biotechnol. 2021 Jan;39(1):13-17. doi: 10.1038/s41587-020-00762-x.
2021

Cellular Models and High-Throughput Screening for Genetic Causality of Intellectual Disability.

Fell CW, Nagy V.
Trends Mol Med. 2021 Mar;27(3):220-230. doi: 10.1016/j.molmed.2020.12.003. Epub 2021 Jan 2.