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2023

Extracorporeal photopheresis as an immunomodulatory treatment modality for chronic GvHD and the importance of emerging biomarkers

Ines Bojanic, Nina Worel, Carolina P Pacini, Georg Stary, Agnieszka Piekarska, Aisling M Flinn, Kimberly J Schell, Andrew R Gennery, Robert Knobler, João F Lacerda, Hildegard T Greinix, Drazen Pulanic, Rachel E Crossland.
Front Immunol. 2023 Feb 17;14:1086006. doi: 10.3389/fimmu.2023.1086006. eCollection 2023.
2023

Polymerase-δ-deficiency as a novel cause of inborn cancer predisposition associated with human papillomavirus infection

Johanna Strobl, Bettina Huber, Raul Jimenez Heredia, Reinhard Kirnbauer, Kaan Boztug, Georg Stary.
Br J Dermatol. 2023 Apr 20;188(5):684-685. doi: 10.1093/bjd/ljad021.
2023

Correction: Disturbances in microbial skin recolonization and cutaneous immune response following allogeneic stem cell transfer

Nadine Bayer, Bela Hausmann, Ram Vinay Pandey, Florian Deckert, Laura-Marie Gail, Johanna Strobl, Petra Pjevac, Christoph Krall, Luisa Unterluggauer, Anna Redl, Victoria Bachmayr, Lisa Kleissl, Marion Nehr, Rasmus Kirkegaard, Athanasios Makristathis, Martin L Watzenboeck, Robert Nica, Clement Staud, Lukas Hammerl, Philipp Wohlfarth, Rupert C Ecker, Sylvia Knapp, Werner Rabitsch, David Berry, Georg Stary.
Leukemia. 2023 Mar;37(3):724. doi: 10.1038/s41375-023-01839-7.
2023

In vivo screening unveils pervasive RNA-binding protein dependencies in leukemic stem cells and identifies ELAVL1 as a therapeutic target

Ana Vujovic, Laura de Rooij, Ava Keyvani Chahi, He Tian Chen, Brian A Yee, Sampath K Loganathan, Lina Liu, Derek C H Chan, Amanda Tajik, Emily Tsao, Steven Moreira, Pratik Joshi, Joshua Xu, Nicholas Wong, Zaldy Balde, Soheil Jahangiri, Sasan Zandi, Stefan Aigner, John E Dick, Mark D Minden, Daniel Schramek, Gene W Yeo, Kristin J Hope.
Blood Cancer Discov. 2023 Feb 10:BCD-22-0086. doi: 10.1158/2643-3230.BCD-22-0086. Online ahead of print.
2023

Single-cell and spatial transcriptomics reveal aberrant lymphoid developmental programs driving granuloma formation

Thomas Krausgruber, Anna Redl, Daniele Barreca, Konstantin Doberer, Daria Romanovskaia, Lina Dobnikar, Maria Guarini, Luisa Unterluggauer, Lisa Kleissl, Denise Atzmüller, Carolina Mayerhofer, Aglaja Kopf, Simona Saluzzo, Clarice X Lim, Praveen Rexie, Thomas Weichhart, Christoph Bock, Georg Stary.
Immunity. 2023 Feb 14;56(2):289-306.e7. doi: 10.1016/j.immuni.2023.01.014. Epub 2023 Feb 6.
2023

Macrophage and monocyte subsets as new therapeutic targets in cancer immunotherapy

B Fendl, A S Berghoff, M Preusser, B Maier.
ESMO Open. 2023 Feb;8(1):100776. doi: 10.1016/j.esmoop.2022.100776. Epub 2023 Feb 1.
2023

A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery

Patrick Essletzbichler, Vitaly Sedlyarov, Fabian Frommelt, Didier Soulat, Leonhard X Heinz, Adrijana Stefanovic, Benedikt Neumayer, Giulio Superti-Furga.
Life Sci Alliance. 2023 Feb 1;6(4):e202201715. doi: 10.26508/lsa.202201715. Print 2023 Apr.
2023

Advancing Targeted Protein Degradation via Multiomics Profiling and Artificial Intelligence

Miquel Duran-Frigola, Marko Cigler, Georg E Winter.
J Am Chem Soc. 2023 Feb 8;145(5):2711-2732. doi: 10.1021/jacs.2c11098. Epub 2023 Jan 27.
2023

LIQUORICE: detection of epigenetic signatures in liquid biopsies based on whole-genome sequencing data

Peter Peneder, Christoph Bock, Eleni M Tomazou.
Bioinform Adv. 2022 Mar 23;2(1):vbac017. doi: 10.1093/bioadv/vbac017. eCollection 2022.
2023

Epigenetic regulation of T cell lineages in skin and blood following hematopoietic stem cell transplantation

Ram Vinay Pandey, Johanna Strobl, Anna Redl, Luisa Unterluggauer, Laura Gail, Lisa Kleissl, Sophie Müller, Denise Atzmüller, Victoria Fife-Gernedl, Thomas Krausgruber, Hanna Knaus, Margit Mitterbauer, Philipp Wohlfarth, Werner Rabitsch, Christoph Bock, Georg Stary.
Clin Immunol. 2023 Mar;248:109245. doi: 10.1016/j.clim.2023.109245. Epub 2023 Jan 23.