2023
Discovery and Mechanistic Elucidation of NQO1-Bioactivatable Small Molecules That Overcome Resistance to Degraders
Bárbara M G Barbosa,
Aikaterini Sfyaki,
Sergi Rafael,
Ferran José-Duran,
Joan Pous,
Carolina Sánchez-Zarzalejo,
Carles Perez-Lopez,
Mar Vilanova,
Marko Cigler,
Marina Gay,
Marta Vilaseca,
Georg E Winter,
Antoni Riera,
Cristina Mayor-Ruiz.
Angew Chem Int Ed Engl. 2024 Mar 18;63(12):e202316730. doi: 10.1002/anie.202316730. Epub 2024 Jan 18.
2023
Decreased platelet activation predicts hepatic decompensation and mortality in patients with cirrhosis
Benedikt S Hofer,
Ksenia Brusilovskaya,
Benedikt Simbrunner,
Lorenz Balcar,
Beate Eichelberger,
Silvia Lee,
Lukas Hartl,
Philipp Schwabl,
Mattias Mandorfer,
Simon Panzer,
Thomas Reiberger,
Thomas Gremmel.
Hepatology. 2023 Dec 27. doi: 10.1097/HEP.0000000000000740. Online ahead of print.
2023
Sex-specific association of visceral and subcutaneous adipose tissue volumes with systemic inflammation and innate immune cells in people living with obesity
Inge C L van den Munckhof,
Harsh Bahrar,
Kiki Schraa,
Tessa Brand,
Rob Ter Horst,
Marinette van der Graaf,
Helena M Dekker,
Rinke Stienstra,
Jacqueline de Graaf,
Leo A B Joosten,
Mihai G Netea,
Niels P Riksen,
Joost H W Rutten.
Int J Obes (Lond). 2024 Apr;48(4):523-532. doi: 10.1038/s41366-023-01444-9. Epub 2023 Dec 22.
2023
Cohesin and CTCF do not assemble TADs in Xenopus sperm and male pronuclei
Gregor Jessberger,
Csilla Várnai,
Roman R Stocsits,
Wen Tang,
Georg Stary,
Jan-Michael Peters.
Genome Res. 2023 Dec 21;33(12):2094-107. doi: 10.1101/gr.277865.123. Online ahead of print.
2023
Human Autosomal Recessive DNA Polymerase Delta 3 Deficiency Presenting as Omenn Syndrome
Maria Rodrigo Riestra,
Bethany A Pillay,
Mathijs Willemsen,
Verena Kienapfel,
Lisa Ehlers,
Selket Delafontaine,
Antoine Pinton,
Marjon Wouters,
Anneleen Hombrouck,
Kate Sauer,
Xavier Bossuyt,
Arnout Voet,
Stefaan J Soenen,
Cecilia Dominguez Conde,
Giorgia Bucciol,
Kaan Boztug,
Stephanie Humblet-Baron,
Aurore Touzart,
Frédéric Rieux-Laucat,
Luigi D Notarangelo,
Leen Moens,
Isabelle Meyts.
J Clin Immunol. 2023 Dec 15;44(1):2. doi: 10.1007/s10875-023-01627-z.
2023
Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling
Amanda Ng,
Fabian Offensperger,
Jose A Cisneros,
Natalie S Scholes,
Monika Malik,
Ludovica Villanti,
Andrea Rukavina,
Evandro Ferrada,
J Thomas Hannich,
Anna Koren,
Stefan Kubicek,
Giulio Superti-Furga,
Georg E Winter.
ACS Chem Biol. 2023 Dec 15;18(12):2464-2473. doi: 10.1021/acschembio.3c00598. Epub 2023 Nov 21.
2023
Multipotent progenitors instruct ontogeny of the superior colliculus
Giselle Cheung,
Florian M Pauler,
Peter Koppensteiner,
Thomas Krausgruber,
Carmen Streicher,
Martin Schrammel,
Natalie Gutmann-Özgen,
Alexis E Ivec,
Christoph Bock,
Ryuichi Shigemoto,
Simon Hippenmeyer.
Neuron. 2024 Jan 17;112(2):230-246.e11. doi: 10.1016/j.neuron.2023.11.009. Epub 2023 Dec 13.
2023
RIF1 regulates early replication timing in murine B cells
Daniel Malzl,
Mihaela Peycheva,
Ali Rahjouei,
Stefano Gnan,
Kyle N Klein,
Mariia Nazarova,
Ursula E Schoeberl,
David M Gilbert,
Sara C B Buonomo,
Michela Di Virgilio,
Tobias Neumann,
Rushad Pavri.
Nat Commun. 2023 Dec 11;14(1):8049. doi: 10.1038/s41467-023-43778-y.
2023
Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8
Evandro Ferrada,
Tabea Wiedmer,
Wen-An Wang,
Fabian Frommelt,
Barbara Steurer,
Christoph Klimek,
Sabrina Lindinger,
Tanja Osthushenrich,
Andrea Garofoli,
Silvia Brocchetti,
Samuel Bradberry,
Jiahui Huang,
Aidan MacNamara,
Lia Scarabottolo,
Gerhard F Ecker,
Anders Malarstig,
Giulio Superti-Furga.
J Mol Biol. 2024 Jan 15;436(2):168383. doi: 10.1016/j.jmb.2023.168383. Epub 2023 Dec 7.
2023
A replicating LCMV-based vaccine for the treatment of solid tumors
Mette-Triin Purde,
Jovana Cupovic,
Yannick A Palmowski,
Ahmad Makky,
Sarah Schmidt,
Alexander Rochwarger,
Fabienne Hartmann,
Felix Stemeseder,
Alexander Lercher,
Marie-Therese Abdou,
David Bomze,
Lenka Besse,
Fiamma Berner,
Thomas Tüting,
Michael Hölzel,
Andreas Bergthaler,
Stefan Kochanek,
Burkhard Ludewig,
Henning Lauterbach,
Klaus K Orlinger,
Tobias Bald,
Andrea Schietinger,
Christian Schürch,
Sandra S Ring,
Lukas Flatz.
Mol Ther. 2024 Feb 7;32(2):426-439. doi: 10.1016/j.ymthe.2023.11.026. Epub 2023 Dec 5.
