2024
Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP
Marko Cigler,
Hana Imrichova,
Fabian Frommelt,
Lucie Caramelle,
Laura Depta,
Andrea Rukavina,
Chrysanthi Kagiou,
J Thomas Hannich,
Cristina Mayor-Ruiz,
Giulio Superti-Furga,
Sonja Sievers,
Alison Forrester,
Luca Laraia,
Herbert Waldmann,
Georg E Winter.
Nat Chem Biol. 2025 Feb;21(2):193-202. doi: 10.1038/s41589-024-01614-4. Epub 2024 Jun 21.
2024
Protein Binder Toolbox for Studies of Solute Carrier Transporters
Zuzana Gelová,
Alvaro Ingles-Prieto,
Tina Bohstedt,
Fabian Frommelt,
Gamma Chi,
Yung-Ning Chang,
Julio Garcia,
Gernot Wolf,
Lucia Azzollini,
Sara Tremolada,
Andreea Scacioc,
Jesper S Hansen,
Iciar Serrano,
Aida Droce,
Jenifer Cuesta Bernal,
Nicola A Burgess-Brown,
Elisabeth P Carpenter,
Katharina L Dürr,
Peter Kristensen,
Eric R Geertsma,
Saša Štefanić,
Lia Scarabottolo,
Tabea Wiedmer,
Vera Puetter,
David B Sauer,
Giulio Superti-Furga.
J Mol Biol. 2024 Aug 15;436(16):168665. doi: 10.1016/j.jmb.2024.168665. Epub 2024 Jun 13.
2024
Gastrointestinal Biofilms: Endoscopic Detection, Disease Relevance, and Therapeutic Strategies
Bernhard Jandl,
Satish Dighe,
Maximillian Baumgartner,
Athanasios Makristathis,
Christoph Gasche,
Markus Muttenthaler.
Gastroenterology. 2024 Nov;167(6):1098-1112.e5. doi: 10.1053/j.gastro.2024.04.032. Epub 2024 Jun 12.
2024
Targeting T cell plasticity in kidney and gut inflammation by pooled single-cell CRISPR screening
Leon U B Enk,
Malte Hellmig,
Kristoffer Riecken,
Christoph Kilian,
Paul Datlinger,
Saskia L Jauch-Speer,
Tobias Neben,
Zeba Sultana,
Varshi Sivayoganathan,
Alina Borchers,
Hans-Joachim Paust,
Yu Zhao,
Nariaki Asada,
Shuya Liu,
Theodora Agalioti,
Penelope Pelczar,
Thorsten Wiech,
Christoph Bock,
Tobias B Huber,
Samuel Huber,
Stefan Bonn,
Nicola Gagliani,
Boris Fehse,
Ulf Panzer,
Christian F Krebs.
Sci Immunol. 2024 Jun 14;9(96):eadd6774. doi: 10.1126/sciimmunol.add6774. Epub 2024 Jun 14.
2024
Monitoring subcellular protein localization at scale in live cells
Jiří Reiniš,
Andreas Reicher.
Nat Rev Mol Cell Biol. 2024 Sep;25(9):673. doi: 10.1038/s41580-024-00749-5.
2024
Reticulated platelets in cirrhosis - Just a surrogate for thrombocytopenia?
Benedikt Silvester Hofer,
Thomas Reiberger,
Thomas Gremmel.
Dig Liver Dis. 2024 Sep;56(9):1641-1642. doi: 10.1016/j.dld.2024.05.029. Epub 2024 Jun 8.
2024
Development of a live cell assay for the zinc transporter ZnT8
Lucia Azzollini,
Dolores Del Prete,
Gernot Wolf,
Christoph Klimek,
Mattia Saggioro,
Fernanda Ricci,
Eirini Christodoulaki,
Tabea Wiedmer,
Alvaro Ingles-Prieto,
Giulio Superti-Furga,
Lia Scarabottolo.
SLAS Discov. 2024 Jul;29(5):100166. doi: 10.1016/j.slasd.2024.100166. Epub 2024 Jun 5.
2024
Single-cell RNA sequencing of cystic fibrosis liver disease explants reveals endothelial complement activation
Mathias Declercq,
Lucas Treps,
Vincent Geldhof,
Nadine V Conchinha,
Laura P M H de Rooij,
Abhishek Subramanian,
Magalie Feyeux,
Marine Cotinat,
Bram Boeckx,
Stefan Vinckier,
Lieven Dupont,
Francois Vermeulen,
Mieke Boon,
Marijke Proesmans,
Louis Libbrecht,
Jacques Pirenne,
Diethard Monbaliu,
Ina Jochmans,
Mieke Dewerchin,
Guy Eelen,
Tania Roskams,
Stijn Verleden,
Diether Lambrechts,
Peter Carmeliet,
Peter Witters.
Liver Int. 2024 Sep;44(9):2382-2395. doi: 10.1111/liv.15963. Epub 2024 Jun 7.
2024
Genomic surveillance of SARS-CoV-2 evolution by a centralised pipeline and weekly focused sequencing, Austria, January 2021 to March 2023
Olga Frank,
David Acitores Balboa,
Maria Novatchkova,
Ezgi Özkan,
Marcus Martin Strobl,
Ramesh Yelagandula,
Tanino Guiseppe Albanese,
Lukas Endler,
Fabian Amman,
Vera Felsenstein,
Milanka Gavrilovic,
Melanie Acosta,
Timothej Patocka,
Alexander Vogt,
Ido Tamir,
Julia Klikovits,
Alexander Zoufaly,
Tamara Seitz,
Manuela Födinger,
Andreas Bergthaler,
Alexander Indra,
Daniela Schmid,
Peter Klimek,
Alexander Stark,
Franz Allerberger,
Bernhard Benka,
Katharina Reich,
Luisa Cochella,
Ulrich Elling.
Euro Surveill. 2024 Jun;29(23):2300542. doi: 10.2807/1560-7917.ES.2024.29.23.2300542.
2024
The histone deacetylase HDAC1 controls dendritic cell development and anti-tumor immunity
Cristiano De Sá Fernandes,
Philipp Novoszel,
Tommaso Gastaldi,
Dana Krauß,
Magdalena Lang,
Ramona Rica,
Ana P Kutschat,
Martin Holcmann,
Wilfried Ellmeier,
Davide Seruggia,
Herbert Strobl,
Maria Sibilia.
Cell Rep. 2024 Jun 25;43(6):114308. doi: 10.1016/j.celrep.2024.114308. Epub 2024 Jun 2.
