2024
Bile acid metabolism and signalling in liver disease
Claudia D Fuchs,
Benedikt Simbrunner,
Maximillian Baumgartner,
Clarissa Campbell,
Thomas Reiberger,
Michael Trauner.
J Hepatol. 2025 Jan;82(1):134-153. doi: 10.1016/j.jhep.2024.09.032. Epub 2024 Sep 28.
2024
Aetiology-specific inflammation patterns in patients and rat models of compensated cirrhosis
Benedikt Silvester Hofer,
Benedikt Simbrunner,
Philipp Königshofer,
Ksenia Brusilovskaya,
Oleksandr Petrenko,
Vlad Taru,
Thomas Sorz,
Kerstin Zinober,
Georg Semmler,
Stefan G Kauschke,
Larissa Pfisterer,
Michael Trauner,
Mattias Mandorfer,
Philipp Schwabl,
Thomas Reiberger.
Dig Liver Dis. 2025 Feb;57(2):450-458. doi: 10.1016/j.dld.2024.09.006. Epub 2024 Sep 28.
2024
NUP98 oncofusions in myeloid malignancies: An update on molecular mechanisms and therapeutic opportunities
Milad Rasouli,
Selina Troester,
Florian Grebien,
Bianca F Goemans,
C Michel Zwaan,
Olaf Heidenreich.
Hemasphere. 2024 Sep 25;8(9):e70013. doi: 10.1002/hem3.70013. eCollection 2024 Sep.
2024
Probing the Chemical Space of Guanidino-Carboxylic Acids to Identify the First Blockers of the Creatine-Transporter-1
Clemens V Farr,
Yi Xiao,
Ali El-Kasaby,
Manuel Schupp,
Matej Hotka,
Giovanni di Mauro,
Amy Clarke,
Miryam Pastor Fernandez,
Walter Sandtner,
Thomas Stockner,
Christoph Klade,
Nuno Maulide,
Michael Freissmuth.
Mol Pharmacol. 2024 Nov 18;106(6):319-333. doi: 10.1124/molpharm.124.000995.
2024
CRISPR-CLEAR: Nucleotide-Resolution Mapping of Regulatory Elements via Allelic Readout of Tiled Base Editing
Basheer Becerra,
Sandra Wittibschlager,
Zain M Patel,
Ana P Kutschat,
Justin Delano,
Eric Che,
Anzhelika Karjalainen,
Ting Wu,
Marlena Starrs,
Martin Jankowiak,
Daniel E Bauer,
Davide Seruggia,
Luca Pinello.
bioRxiv [Preprint]. 2024 Sep 9:2024.09.09.612085. doi: 10.1101/2024.09.09.612085.
2024
High-temperature water unlocks urea as nitrogen-source towards imidazoles
Fabián Amaya-García,
Lena Schittenhelm,
Miriam M Unterlass.
Green Chem. 2024 Sep 20;26(20):10411-10421. doi: 10.1039/d4gc01705f. eCollection 2024 Oct 14.
2024
Insights into the multifaceted role of interleukin-37 on human immune cell regulation
Lisa U Teufel,
Vasiliki Matzaraki,
Lukas Folkman,
Rob Ter Horst,
Simone J C F M Moorlag,
Catharina M Mulders-Manders,
Mihai G Netea,
Thomas Krausgruber,
Leo A B Joosten,
Rob J W Arts.
Clin Immunol. 2024 Nov;268:110368. doi: 10.1016/j.clim.2024.110368. Epub 2024 Sep 20.
2024
Amplified centrosomes-more than just a threat
Eva Kiermaier,
Isabel Stötzel,
Marina A Schapfl,
Andreas Villunger.
EMBO Rep. 2024 Oct;25(10):4153-4167. doi: 10.1038/s44319-024-00260-0. Epub 2024 Sep 16.
2024
Diastereoselective hydride transfer enables a synthesis of chiral 1,5-carboxamido-trifluoromethylcarbinols
Roberto Tinelli,
Manuel Schupp,
Immo Klose,
Saad Shaaban,
Boris Maryasin,
Leticia González,
Nuno Maulide.
Chem Sci. 2024 Sep 9;15(38):15751-6. doi: 10.1039/d4sc05049e. Online ahead of print.
2024
Extrapolating Lessons from Targeted Protein Degradation to Other Proximity-Inducing Drugs
Georg E Winter.
ACS Chem Biol. 2024 Oct 18;19(10):2089-2102. doi: 10.1021/acschembio.4c00191. Epub 2024 Sep 12.
