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2011

Rare germline variants in regions of loss of heterozygosity may influence clinical course of hematological malignancies.

Harutyunyan A, Gisslinger B, Klampfl T, Berg T, Bagienski K, Gisslinger H, Kralovics R.
Leukemia. 2011 Nov;25(11):1782-4.
2011

Targeting allosteric regulatory modules in oncoproteins: “drugging the undruggable”.

Hantschel O, Grebien F, Superti-Furga G.
Oncotarget. 2011 Nov;2(11):828-9.
2011

Oxidative damage in multiple sclerosis lesions.

Haider L, Fischer MT, Frischer JM, Bauer J, Hoftberger R, Botond G, Esterbauer H, Binder CJ, Witztum JL, Lassmann H.
Brain. 2011 Jul;134(Pt 7):1914-24.
2011

Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis.

Grebien F, Hantschel O, Wojcik J, Kaupe I, Kovacic B, Wyrzucki AM, Gish GD, Cerny-Reiterer S, Koide A, Beug H, Pawson T, Valent P, Koide S, Superti-Furga G.
Cell. 2011 Oct 14;147(2):306-19.
2011

Type I interferon production induced by Streptococcus pyogenes-derived nucleic acids is required for host protection.

Gratz N, Hartweger H, Matt U, Kratochvill F, Janos M, Sigel S, Drobits B, Li XD, Knapp S, Kovarik P.
PLoS Pathog. 2011 May;7(5):e1001345.
2011

Functional dissection of the TBK1 molecular network.

Goncalves A, Burckstummer T, Dixit E, Scheicher R, Gorna MW, Karayel E, Sugar C, Stukalov A, Berg T, Kralovics R, Planyavsky M, Bennett KL, Colinge J, Superti-Furga G.
PLoS One. 2011;6(9):e23971.
2011

KIT-D816V-independent oncogenic signaling in neoplastic cells in systemic mastocytosis: role of Lyn and Btk activation and disruption by dasatinib and bosutinib.

Gleixner KV, Mayerhofer M, Cerny-Reiterer S, Hormann G, Rix U, Bennett KL, Hadzijusufovic E, Meyer RA, Pickl WF, Gotlib J, Horny HP, Reiter A, Mitterbauer-Hohendanner G, Superti-Furga G, Valent P.
Blood. 2011 Aug 18;118(7):1885-98.
2011

Nested high-resolution melting curve analysis a highly sensitive, reliable, and simple method for detection of JAK2 exon 12 mutations – clinical relevance in the monitoring of polycythemia.

Carillo S, Henry L, Lippert E, Girodon F, Guiraud I, Richard C, Dubois Galopin F, Cleyrat C, Jourdan E, Kralovics R, Hermouet S, Lavabre-Bertrand T.
J Mol Diagn. 2011 May;13(3):263-70.
2011

Global gene disruption in human cells to assign genes to phenotypes by deep sequencing.

Carette JE, Guimaraes CP, Wuethrich I, Blomen VA, Varadarajan M, Sun C, Bell G, Yuan B, Muellner MK, Nijman SM, Ploegh HL, Brummelkamp TR.
Nat Biotechnol. 2011 Jun;29(6):542-6.
2011

Initial characterization of the human central proteome.

Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Burckstummer T, Bennett KL, Superti-Furga G, Colinge J.
BMC Syst Biol. 2011;5:17.