2014
A strand-specific switch in noncoding transcription switches the function of a Polycomb/Trithorax response element.
Herzog VA,
Lempradl A,
Trupke J,
Okulski H,
Altmutter C,
Ruge F,
Boidol B,
Kubicek S,
Schmauss G,
Aumayr K,
Ruf M,
Pospisilik A,
Dimond A,
Senergin HB,
Vargas ML,
Simon JA,
Ringrose L.
Nat Genet. 2014 Sep;46(9):973-81. doi: 10.1038/ng.3058. Epub 2014 Aug 10.
2014
Identification of kinase inhibitor targets in the lung cancer microenvironment by chemical and phosphoproteomics.
Gridling M,
Ficarro S,
Breitwieser FP,
Song L,
Parapatics K,
Colinge J,
Haura EB,
Marto J,
Superti-Furga G,
Bennett KL,
Rix U.
Mol Cancer Ther. 2014 Sep 4. pii: molcanther.0152.2014. [Epub ahead of print]
2014
Atheroprotective immunization with malondialdehyde modified LDL is hapten-specific and dependent on advanced MDA-adducts: Implications for development of an atheroprotective vaccine.
Gonen A,
Hansen LF,
Turner WW,
Montano EN,
Que X,
Rafia A,
Chou MY,
Wiesner P,
Tsiantoulas D,
Corr M,
VanNieuwenhze MS,
Tsimikas S,
Binder CJ,
Witztum JL,
Hartvigsen K.
J Lipid Res. 2014 Oct;55(10):2137-55. doi: 10.1194/jlr.M053256. Epub 2014 Aug 20.
2014
Evaluating the promiscuous nature of tyrosine kinase inhibitors assessed in A431 epidermoid carcinoma cells by both chemical- and phosphoproteomics.
Giansanti P,
Preisinger C,
Huber KV,
Gridling M,
Superti-Furga G,
Bennett KL,
Heck AJ.
ACS Chem Biol. 2014 Jul 18;9(7):1490-8. doi: 10.1021/cb500116c. Epub 2014 May 14.
2014
The lysine methyltransferase SMYD3 interacts with hepatitis C virus NS5A and is a negative regulator of viral particle production.
Eberle CA,
Zayas M,
Stukalov A,
Pichlmair A,
Alvisi G,
Müller AC,
Bennett KL,
Bartenschlager R,
Superti-Furga G.
Virology. 2014 Aug;462-463:34-41. doi: 10.1016/j.virol.2014.05.016. Epub 2014 Jun 14.
2014
Regulation of DNA methylation patterns by CK2-mediated phosphorylation of Dnmt3a.
Deplus R,
Blanchon L,
Rajavelu A,
Boukaba A,
Defrance M,
Luciani J,
Rothé F,
Dedeurwaerder S,
Denis H,
Brinkman AB,
Simmer F,
Müller F,
Bertin B,
Berdasco M,
Putmans P,
Calonne E,
Litchfield DW,
de Launoit Y,
Jurkowski TP,
Stunnenberg HG,
Bock C,
Sotiriou C,
Fraga MF,
Esteller M,
Jeltsch A,
Fuks F.
Cell Rep. 2014 Aug 7;8(3):743-53. doi: 10.1016/j.celrep.2014.06.048. Epub 2014 Jul 24.
2014
Building and exploring an integrated human kinase network: global organization and medical entry points.
Colinge J,
César-Razquin A,
Huber K,
Breitwieser FP,
Májek P,
Superti-Furga G.
J Proteomics. 2014 Jul 31;107:113-27. doi: 10.1016/j.jprot.2014.03.028. Epub 2014 Apr 3.
2014
Quantitative-proteomic comparison of alpha and Beta cells to uncover novel targets for lineage reprogramming.
Choudhary A,
Hu He K,
Mertins P,
Udeshi ND,
Dančík V,
Fomina-Yadlin D,
Kubicek S,
Clemons PA,
Schreiber SL,
Carr SA,
Wagner BK.
PLoS One. 2014 Apr 23;9(4):e95194. doi: 10.1371/journal.pone.0095194.
2014
From Janus kinase 2 to calreticulin: the clinically relevant genomic landscape of myeloproliferative neoplasms.
Cazzola M,
Kralovics R.
Blood. 2014 Jun 12;123(24):3714-9. doi: 10.1182/blood-2014-03-530865. Epub 2014 Apr 30.
2014
JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia.
Boztug K,
Järvinen PM,
Salzer E,
Racek T,
Mönch S,
Garncarz W,
Gertz EM,
Schäffer AA,
Antonopoulos A,
Haslam SM,
Schieck L,
Puchałka J,
Diestelhorst J,
Appaswamy G,
Lescoeur B,
Giambruno R,
Bigenzahn JW,
Elling U,
Pfeifer D,
Conde CD,
Albert MH,
Welte K,
Brandes G,
Sherkat R,
van der Werff Ten Bosch J,
Rezaei N,
Etzioni A,
Bellanné-Chantelot C,
Superti-Furga G,
Penninger JM,
Bennett KL,
von Blume J,
Dell A,
Donadieu J,
Klein C.
Nat Genet. 2014 Sep;46(9):1021-7. doi: 10.1038/ng.3069. Epub 2014 Aug 17.