2025
Chemokine Receptor Profiles as Predictors of Survival and Early Progression in Follicular Lymphoma
Antonella Zupo,
Katrin Pansy,
Lukas Gaksch,
Julia Waldhart,
Andrea Brunner,
Johanna Strobl,
Marta Szmyra-Polomka,
Sandra Haingartner,
Peter V Tomazic,
Hildegard T Greinix,
Barbara Uhl,
Julia Feichtinger,
Georg Stary,
Johannes Haybaeck,
Fotini Rosi Vagena,
Martin Zacharias,
Christine Beham-Schmid,
Peter Neumeister,
Katharina Theresa Prochazka,
Alexander J A Deutsch.
EJHaem. 2025 Aug 28;6(5):e70131. doi: 10.1002/jha2.70131. eCollection 2025 Oct.
2025
Bacillus Calmette-Guérin-induced trained immunity potentiates TH17 responses in vitro
Leonie S Helder,
Laszlo A Groh,
Vasiliki Matzaraki,
Rob Ter Horst,
Gert Jan Scheffer,
Leo A B Joosten,
Mihai G Netea,
Anaisa V Ferreira.
J Leukoc Biol. 2025 Sep 1;117(9):qiaf123. doi: 10.1093/jleuko/qiaf123.
2025
Quantitative profiling of human brain organoid cell diversity across four protocols and multiple cell lines
Julia Naas,
Meritxell Balmaña,
Laurenz Holcik,
Maria Novatchkova,
Lina Dobnikar,
Thomas Krausgruber,
Sabrina Ladstätter,
Christoph Bock,
Arndt von Haeseler,
Christopher Esk,
Jürgen A Knoblich.
Cell Rep. 2025 Sep 23;44(9):116168. doi: 10.1016/j.celrep.2025.116168. Epub 2025 Aug 26.
2025
Mitochondrial ROS drive foam cell formation via STAT5 signaling in atherosclerosis
Laura Boccuni,
Frieda Marka,
Manuel Salzmann,
Alessia Schirripa,
Elisabeth Ableitner,
Magdalena Siller,
Mira Brekalo,
Patrick Haider,
Stefan Stojkovic,
Christoph Neumayer,
Tiit Örd,
Karoline Kollmann,
Alice Assinger,
Thomas Decker,
Thomas Köcher,
Michael B Fischer,
Marion Mußbacher,
Andreas Bergthaler,
Christian Hengstenberg,
Bruno K Podesser,
Minna U Kaikkonen,
Johann Wojta,
Philipp J Hohensinner.
Sci Adv. 2025 Aug 29;11(35):eadw9952. doi: 10.1126/sciadv.adw9952. Epub 2025 Aug 27.
2025
Single-cell multi-omics characterize colorectal tumors, adjacent healthy tissue and matched (tumor) organoids identifying CRC-unique features
Zhijun Yu,
Merel Derksen,
Brigit M Te Pas,
Sabrina Ladstätter,
Rene Overmeer,
Peter Brazda,
Marc van de Wetering,
Farzin Pourfarzad,
Robert G J Vries,
Wout Megchelenbrink,
Christoph Bock,
Lucia Altucci,
Hendrik G Stunnenberg.
Int J Cancer. 2025 Dec 15;157(12):2619-2634. doi: 10.1002/ijc.70103. Epub 2025 Aug 23.
2025
Opportunities in proximity modulation: Bridging academia and industry
Ivan Dikic,
Cristina Mayor-Ruiz,
Georg E Winter,
Kerstin Koch,
Alessio Ciulli,
Nicolas H Thomä.
Mol Cell. 2025 Aug 21;85(16):3012-3022. doi: 10.1016/j.molcel.2025.07.018.
2025
Image-based drug screening combined with molecular profiling identifies signatures and drivers of therapy resistance in pediatric AML
Ben Haladik,
Margarita Maurer-Granofszky,
Peter Zoescher,
Raul Jimenez-Heredia,
Alexandra Frohne,
Anna Segarra-Roca,
Chloe Casey,
Felix Kartnig,
Sarah Giuliani,
Christina Rashkova,
Peter Repiscak,
Michael N Dworzak,
Giulio Superti-Furga,
Kaan Boztug.
Cell Rep Med. 2025 Sep 16;6(9):102304. doi: 10.1016/j.xcrm.2025.102304. Epub 2025 Aug 20.
2025
Integrated time-series analysis and high-content CRISPR screening delineate the dynamics of macrophage immune regulation
Peter Traxler,
Stephan Reichl,
Lukas Folkman,
Lisa Shaw,
Victoria Fife,
Amelie Nemc,
Djurdja Pasajlic,
Anna Kusienicka,
Daniele Barreca,
Nikolaus Fortelny,
André F Rendeiro,
Florian Halbritter,
Wolfgang Weninger,
Thomas Decker,
Matthias Farlik,
Christoph Bock.
Cell Syst. 2025 Aug 20;16(8):101346. doi: 10.1016/j.cels.2025.101346. Epub 2025 Aug 8.
2025
An unexpected tumor-resistant phenotype from floxing PAK1 in a mouse model of colitis associated cancer
Kristine Jimenez,
Lambert Lindeck-Pozza,
Adrian P Frick,
Maximilian Baumgartner,
Felix Haller,
Christina Gmainer,
Anita Krnjic,
Anton Klotz,
Manuela Jambrich,
Thomas Köcher,
Vineeta Khare,
Christoph Gasche.
Sci Rep. 2025 Aug 9;15(1):29174. doi: 10.1038/s41598-025-12082-8.
2025
Unveiling genetic signatures of immune response in immune-related diseases through single-cell eQTL analysis across diverse conditions
Zhenhua Zhang,
Wenchao Li,
Qiuyao Zhan,
Michelle Aillaud,
Javier Botey-Bataller,
Martijn Zoodsma,
Rob Ter Horst,
Leo A B Joosten,
Christoph Bock,
Leon N Schulte,
Cheng-Jian Xu,
Mihai G Netea,
Marc Jan Bonder,
Yang Li.
Nat Commun. 2025 Aug 4;16(1):7134. doi: 10.1038/s41467-025-61192-4.
