| Year | Paper |
|---|---|
| 2020 | Rendeiro AF, Krausgruber T, Fortelny N, Zhao F, Penz T, Farlik M, Schuster LC, Nemc A, Tasnády S, Réti M, Mátrai Z, Alpár D, Bödör C, Schmidl C, Bock C. Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib response in CLL. Nat Commun. 2020 Jan 29;11(1):577. doi: 10.1038/s41467-019-14081-6. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31996669 |
| 2020 | Girardi E, César-Razquin A, Lindinger S, Papakostas K, Konecka J, Hemmerich J, Kickinger S, Kartnig F, Gürtl B, Klavins K, Sedlyarov V, Ingles-Prieto A, Fiume G, Koren A, Lardeau CH, Kumaran Kandasamy R, Kubicek S, Ecker GF, Superti-Furga G. A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs. Nat Chem Biol. 2020 Apr;16(4):469-478. doi: 10.1038/s41589-020-0483-3. Epub 2020 Mar 9. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32152546 |
| 2020 | Marquina-Sanchez B, Fortelny N, Farlik M, Vieira A, Collombat P, Bock C, Kubicek S. Single-cell RNA-seq with spike-in cells enables accurate quantification of cell-specific drug effects in pancreatic islets. Genome Biol. 2020 May 6;21(1):106. doi: 10.1186/s13059-020-02006-2. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32375897 |
| 2020 | Bensimon A, Pizzagalli MD, Kartnig F, Dvorak V, Essletzbichler P, Winter GE, Superti-Furga G. Targeted Degradation of SLC Transporters Reveals Amenability of Multi-Pass Transmembrane Proteins to Ligand-Induced Proteolysis. Cell Chem Biol. 2020 Apr 18. pii: S2451-9456(20)30117-3. doi: 10.1016/j.chembiol.2020.04.003. [Epub ahead of print] Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32386596 |
| 2020 | Jühling F, Hamdane N, Crouchet E, Li S, El Saghire H, Mukherji A, Fujiwara N, Oudot MA, Thumann C, Saviano A, Roca Suarez AA, Goto K, Masia R, Sojoodi M, Arora G, Aikata H, Ono A, Tabrizian P, Schwartz M, Polyak SJ, Davidson I, Schmidl C, Bock C, Schuster C, Chayama K, Pessaux P, Tanabe KK, Hoshida Y, Zeisel MB, Duong FH, Fuchs BC, Baumert TF. Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma. Gut. 2020 Mar 26:gutjnl-2019-318918. doi: 10.1136/gutjnl-2019-318918. Epub ahead of print. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32217639 |
| 2020 | Balligand T, Achouri Y, Pecquet C, Gaudray G, Colau D, Hug E, Rahmani Y, Stroobant V, Plo I, Vainchenker W, Kralovics R, Van den Eynde BJ, Defour JP, Constantinescu SN. Knock-in of murine Calr del52 induces essential thrombocythemia with slow-rising dominance in mice and reveals key role of Calr exon 9 in cardiac development. Leukemia. 2020 Feb;34(2):510-521. doi: 10.1038/s41375-019-0538-1. Epub 2019 Aug 30. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31471561 |
| 2020 | Köstel Bal S, Pazmandi J, Boztug K, Özen S. Rheumatological manifestations in inborn errors of immunity. Pediatr Res. 2020 Jan;87(2):293-299. doi: 10.1038/s41390-019-0600-8. Epub 2019 Oct 3. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31581173 |
| 2020 | Göschl L, Winkler S, Dmytrus J, Heredia RJ, Lagler H, Ramharter M, Scheinecker C, Bonelli M, Schmetterer K, Pickl WF, Grabmeier-Pfistershammer K, Hershfield MS, Boztug K, Förster-Waldl E, Gualdoni GA. Unreported Missense Mutation in the Dimerization Domain of ADA2 Leads to ADA2 Deficiency Associated with Severe Oral Ulcers and Neutropenia in a Female Somalian Patient-Addendum to the Genotype-Phenotype Puzzle. J Clin Immunol. 2020 Jan;40(1):223-226. doi: 10.1007/s10875-019-00700-w. Epub 2019 Nov 4. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31686313 |
| 2020 | Cinquina V, Calvigioni D, Farlik M, Halbritter F, Fife-Gernedl V, Shirran SL, Fuszard MA, Botting CH, Poullet P, Piscitelli F, Máté Z, Szabó G, Yanagawa Y, Kasper S, Di Marzo V, Mackie K, McBain CJ, Bock C, Keimpema E, Harkany T. Life-long epigenetic programming of cortical architecture by maternal 'Western' diet during pregnancy. Mol Psychiatry. 2020 Jan;25(1):22-36. doi: 10.1038/s41380-019-0580-4. Epub 2019 Nov 18. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31735910 |
| 2020 | Jia R, Kralovics R. Progress in elucidation of molecular pathophysiology of myeloproliferative neoplasms and its application to therapeutic decisions. Int J Hematol. 2020 Feb;111(2):182-191. doi: 10.1007/s12185-019-02778-9. Epub 2019 Nov 18. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31741139 |
| 2020 | Tesch VK, Abolhassani H, Shadur B, Zobel J, Mareika Y, Sharapova S, Karakoc- Aydiner E, Rivière JG, Garcia-Prat M, Moes N, Haerynck F, Gonzales-Granado LI, Santos Pérez JL, Mukhina A, Shcherbina A, Aghamohammadi A, Hammarström L, Dogu F, Haskologlu S, İkincioğulları AI, Köstel Bal S, Baris S, Kilic SS, Karaca NE, Kutukculer N, Girschick H, Kolios A, Keles S, Uygun V, Stepensky P, Worth A, van Montfrans JM, Peters AMJ, Meyts I, Adeli M, Marzollo A, Padem N, Khojah AM, Chavoshzadeh Z, Avbelj Stefanija M, Bakhtiar S, Florkin B, Meeths M, Gamez L, Grimbacher B, Seppänen MRJ, Lankester A, Gennery AR, Seidel MG; Inborn Errors, Clinical, and Registry Working Parties of the European Society for Blood and Marrow Transplantation and the European Society for Immunodeficiencies. Long- term outcome of LRBA deficiency in 76 patients after various treatment modalities as evaluated by the immune deficiency and dysregulation activity (IDDA) score. J Allergy Clin Immunol. 2020 May;145(5):1452-1463. doi: 10.1016/j.jaci.2019.12.896. Epub 2019 Dec 27. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31887391 |
| 2020 | Hanzl A, Winter GE. Targeted protein degradation: current and future challenges. Curr Opin Chem Biol. 2020 Jan 2;56:35-41. doi: 10.1016/j.cbpa.2019.11.012. Epub ahead of print. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31901786 |
| 2020 | Jaeger MG, Winter GE. Expanding the Degradable Proteome: Designing PROTACs by the Book. Cell Chem Biol. 2020 Jan 16;27(1):14-16. doi: 10.1016/j.chembiol.2019.12.009. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31951815 |
| 2020 | Quijada-Álamo M, Hernández-Sánchez M, Alonso-Pérez V, Rodríguez-Vicente AE, García-Tuñón I, Martín-Izquierdo M, Hernández-Sánchez JM, Herrero AB, Bastida JM, San Segundo L, Gruber M, García JL, Yin S, Ten Hacken E, Benito R, Ordóñez JL, Wu CJ, Hernández-Rivas JM. CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del(11q) CLL cells to dual BCR and PARP inhibition. Leukemia. 2020 Jan 23. doi: 10.1038/s41375-020-0714-3. Epub ahead of print. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31974435 |
| 2020 | Sladky VC, Knapp K, Soratroi C, Heppke J, Eichin F, Rocamora-Reverte L, Szabo TG, Bongiovanni L, Westendorp B, Moreno E, van Liere EA, Bakker B, Spierings DCJ, Wardenaar R, Pereyra D, Starlinger P, Schultze S, Trauner M, Stojakovic T, Scharnagl H, Fava LL, Foijer F, de Bruin A, Villunger A. E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration. Dev Cell. 2020 Feb 10;52(3):335-349.e7. doi: 10.1016/j.devcel.2019.12.016. Epub 2020 Jan 23. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31983631 |
| 2020 | Thian M, Hoeger B, Kamnev A, Poyer F, Köstel Bal S, Caldera M, Jiménez- Heredia R, Huemer J, Pickl WF, Groß M, Ehl S, Lucas CL, Menche J, Hutter C, Attarbaschi A, Dupré L, Boztug K. Germline biallelic PIK3CG mutations in a multifaceted immunodeficiency with immune dysregulation. Haematologica. 2020 Jan 30:haematol.2019.231399. doi: 10.3324/haematol.2019.231399. Epub ahead of print. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32001535 |
| 2020 | Gisslinger H, Klade C, Georgiev P, Krochmalczyk D, Gercheva-Kyuchukova L, Egyed M, Rossiev V, Dulicek P, Illes A, Pylypenko H, Sivcheva L, Mayer J, Yablokova V, Krejcy K, Grohmann-Izay B, Hasselbalch HC, Kralovics R, Kiladjian JJ; PROUD-PV Study Group. Ropeginterferon alfa-2b versus standard therapy for polycythaemia vera (PROUD-PV and CONTINUATION-PV): a randomised, non- inferiority, phase 3 trial and its extension study. Lancet Haematol. 2020 Mar;7(3):e196-e208. doi: 10.1016/S2352-3026(19)30236-4. Epub 2020 Jan 31. Erratum in: Lancet Haematol. 2020 Feb 25. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32014125 |
| 2020 | Haschka MD, Karbon G, Soratroi C, O'Neill KL, Luo X, Villunger A. MARCH5-dependent degradation of MCL1/NOXA complexes defines susceptibility to antimitotic drug treatment. Cell Death Differ. 2020 Feb 3. doi: 10.1038/s41418-020-0503-6. Epub ahead of print. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32015503 |
| 2020 | Peña-Blanco A, Haschka MD, Jenner A, Zuleger T, Proikas-Cezanne T, Villunger A, García-Sáez AJ. Drp1 modulates mitochondrial stress responses to mitotic arrest. Cell Death Differ. 2020 Mar 19. doi: 10.1038/s41418-020-0527-y. Epub ahead of print. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32203171 |
| 2020 | Strobl J, Pandey RV, Krausgruber T, Kleissl L, Reininger B, Herac M, Bayer N, Krall C, Wohlfarth P, Mitterbauer M, Kalhs P, Rabitsch W, Bock C, Hopfinger G, Stary G. Anti-Apoptotic Molecule BCL2 Is a Therapeutic Target in Steroid- Refractory Graft-Versus-Host Disease. J Invest Dermatol. 2020 Apr 2:S0022-202X(20)31252-5. doi: 10.1016/j.jid.2020.02.029. Epub ahead of print. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32247860 |
| 2020 | Taublaender MJ, Mezzavilla S, Thiele S, Glöcklhofer F, Unterlass MM. Hydrothermal Generation of Conjugated Polymers Using the Example of Pyrrone Polymers and Polybenzimidazoles. Angew Chem Int Ed Engl. 2020 Apr 7. doi: 10.1002/anie.202000367. Epub ahead of print. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32255546 |
| 2020 | Lorenzini T, Fliegauf M, Klammer N, Frede N, Proietti M, Bulashevska A, Camacho-Ordonez N, Varjosalo M, Kinnunen M, de Vries E, van der Meer JWM, Ameratunga R, Roifman CM, Schejter YD, Kobbe R, Hautala T, Atschekzei F, Schmidt RE, Schröder C, Stepensky P, Shadur B, Pedroza LA, van der Flier M, Martínez- Gallo M, Gonzalez-Granado LI, Allende LM, Shcherbina A, Kuzmenko N, Zakharova V, Neves JF, Svec P, Fischer U, Ip W, Bartsch O, Barış S, Klein C, Geha R, Chou J, Alosaimi M, Weintraub L, Boztug K, Hirschmugl T, Dos Santos Vilela MM, Holzinger D, Seidl M, Lougaris V, Plebani A, Alsina L, Piquer-Gibert M, Deyà-Martínez A, Slade CA, Aghamohammadi A, Abolhassani H, Hammarström L, Kuismin O, Helminen M, Allen HL, Thaventhiran JE, Freeman AF, Cook M, Bakhtiar S, Christiansen M, Cunningham-Rundles C, Patel NC, Rae W, Niehues T, Brauer N, Syrjänen J, Seppänen MRJ, Burns SO, Tuijnenburg P, Kuijpers TW; NIHR-BioResource – Rare Diseases Consortium, Warnatz K, Grimbacher B. Characterization of the clinical and immunologic phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations. J Allergy Clin Immunol. 2020 Apr 9:S0091-6749(20)30422-X. doi: 10.1016/j.jaci.2019.11.051. Epub ahead of print. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32278790 |
| 2020 | Rojahn TB, Vorstandlechner V, Krausgruber T, Bauer WM, Alkon N, Bangert C, Thaler FM, Sadeghyar F, Fortelny N, Gernedl V, Rindler K, Elbe-Bürger A, Bock C, Mildner M, Brunner PM. Single-cell transcriptomics combined with interstitial fluid proteomics defines cell-type-specific immune regulation in atopic dermatitis. J Allergy Clin Immunol. 2020 Apr 25:S0091-6749(20)30556-X. doi: 10.1016/j.jaci.2020.03.041. Epub ahead of print. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32344053 |
| 2020 | Brunner SB, Marculescu R, Scheiner B, Schwabl P, Bucsics T, Stadlmann A, Bauer DJM, Paternostro R, Eigenbauer E, Pinter M, Stättermayer AF, Trauner M, Mandorfer M, Reiberger T. Non-invasive detection of portal hypertension by enhanced liver fibrosis score in patients with different aetiologies of advanced chronic liver disease. Liver Int. 2020 May 2. doi: 10.1111/liv.14498. Epub ahead of print. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32358998 |
| 2020 | Fagone P, Ciurleo R, Lombardo SD, Iacobello C, Palermo CI, Shoenfeld Y, Bendtzen K, Bramanti P, Nicoletti F. Transcriptional landscape of SARS-CoV-2 infection dismantles pathogenic pathways activated by the virus, proposes unique sex-specific differences and predicts tailored therapeutic strategies. Autoimmun Rev. 2020 May 3:102571. doi: 10.1016/j.autrev.2020.102571. Epub ahead of print. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32376402 |
| 2020 | Gasteiger LM, Robinson PN, Pazmandi J, Boztug K, Seppänen MRJ, Seidel MG; Registry Working Party of the European Society for Immunodeficiencies (ESID). Supplementation of the ESID registry working definitions for the clinical diagnosis of inborn errors of immunity with encoded human phenotype ontology (HPO) terms. J Allergy Clin Immunol Pract. 2020 May;8(5):1778. doi: 10.1016/j.jaip.2020.02.019. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32389282 |
| 2020 | Sladky VC, Villunger A. Uncovering the PIDDosome and caspase-2 as regulators of organogenesis and cellular differentiation. Cell Death Differ. 2020 May 15. doi: 10.1038/s41418-020-0556-6. Epub ahead of print. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32415279 |
| 2020 | Çipe FE, Aydoğmuş Ç, Baskın K, Keskindemirci G, Garncarz W, Boztuğ K. A rare case of syndromic severe congenital neutropenia: JAGN1 mutation. Turk J Pediatr. 2020;62(2):326-331. doi: 10.24953/turkjped.2020.02.022. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32419428 |
| 2020 | Heinz LX, Lee J, Kapoor U, Kartnig F, Sedlyarov V, Papakostas K, César- Razquin A, Essletzbichler P, Goldmann U, Stefanovic A, Bigenzahn JW, Scorzoni S, Pizzagalli MD, Bensimon A, Müller AC, King FJ, Li J, Girardi E, Mbow ML, Whitehurst CE, Rebsamen M, Superti-Furga G. TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9. Nature. 2020 May;581(7808):316-322. doi: 10.1038/s41586-020-2282-0. Epub 2020 May 13. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32433612 |
| 2020 | Surface LE, Burrow DT, Li J, Park J, Kumar S, Lyu C, Song N, Yu Z, Rajagopal A, Bae Y, Lee BH, Mumm S, Gu CC, Baker JC, Mohseni M, Sum M, Huskey M, Duan S, Bijanki VN, Civitelli R, Gardner MJ, McAndrew CM, Ricci WM, Gurnett CA, Diemer K, Wan F, Costantino CL, Shannon KM, Raje N, Dodson TB, Haber DA, Carette JE, Varadarajan M, Brummelkamp TR, Birsoy K, Sabatini DM, Haller G, Peterson TR. ATRAID regulates the action of nitrogen-containing bisphosphonates on bone. Sci Transl Med. 2020 May 20;12(544):eaav9166. doi: 10.1126/scitranslmed.aav9166. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32434850 |
| 2020 | Maurer B, Nivarthi H, Wingelhofer B, Pham HTT, Schlederer M, Suske T, Grausenburger R, Schiefer AI, Prchal-Murphy M, Chen D, Winkler S, Merkel O, Kornauth C, Hofbauer M, Hochgatterer B, Hoermann G, Hoelbl-Kovacic A, Prochazkova J, Lobello C, Cumaraswamy AA, Latzka J, Kitzwögerer M, Chott A, Janikova A, Pospíšilova Š, Loizou JI, Kubicek S, Valent P, Kolbe T, Grebien F, Kenner L, Gunning PT, Kralovics R, Herling M, Müller M, Rülicke T, Sexl V, Moriggl R. High activation of STAT5A drives peripheral T-cell lymphoma and leukemia. Haematologica. 2020 Jan 31;105(2):435-447. doi: 10.3324/haematol.2019.216986. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31123029 |
| 2020 | Ilott NE, Bollrath J, Danne C, Schiering C, Shale M, Adelmann K, Krausgruber T, Heger A, Sims D, Powrie F. Correction: Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling. ISME J. 2020 Mar;14(3):879. doi: 10.1038/s41396-019-0539-0. Erratum for: ISME J. 2016 Oct;10(10):2389-404. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31748709 |
| 2020 | Korchynska S, Krassnitzer M, Malenczyk K, Prasad RB, Tretiakov EO, Rehman S, Cinquina V, Gernedl V, Farlik M, Petersen J, Hannes S, Schachenhofer J, Reisinger SN, Zambon A, Asplund O, Artner I, Keimpema E, Lubec G, Mulder J, Bock C, Pollak DD, Romanov RA, Pifl C, Groop L, Hökfelt TG, Harkany T. Life-long impairment of glucose homeostasis upon prenatal exposure to psychostimulants. EMBO J. 2020 Jan 2;39(1):e100882. doi: 10.15252/embj.2018100882. Epub 2019 Nov 21. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31750562 |
| 2020 | Lau A, Avery DT, Jackson K, Lenthall H, Volpi S, Brigden H, Russell AJ, Bier J, Reed JH, Smart JM, Cole T, Choo S, Gray PE, Berglund LJ, Hsu P, Wong M, O'Sullivan M, Boztug K, Meyts I, Uzel G, Notarangelo LD, Brink R, Goodnow CC, Tangye SG, Deenick EK. Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production. J Exp Med. 2020 Feb 3;217(2):e20191336. doi: 10.1084/jem.20191336. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31841125 |
| 2020 | Paternostro R, Pfeiffenberger J, Ferenci P, Stättermayer AF, Stauber RE, Wrba F, Longerich T, Lackner K, Trauner M, Ferlitsch A, Reiberger T, Weiss KH. Non-invasive diagnosis of cirrhosis and long-term disease monitoring by transient elastography in patients with Wilson disease. Liver Int. 2020 Apr;40(4):894-904. doi: 10.1111/liv.14368. Epub 2020 Jan 22. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31898387 |
| 2020 | Delacher M, Imbusch CD, Hotz-Wagenblatt A, Mallm JP, Bauer K, Simon M, Riegel D, Rendeiro AF, Bittner S, Sanderink L, Pant A, Schmidleithner L, Braband KL, Echtenachter B, Fischer A, Giunchiglia V, Hoffmann P, Edinger M, Bock C, Rehli M, Brors B, Schmidl C, Feuerer M. Precursors for Nonlymphoid-Tissue Treg Cells Reside in Secondary Lymphoid Organs and Are Programmed by the Transcription Factor BATF. Immunity. 2020 Feb 18;52(2):295-312.e11. doi: 10.1016/j.immuni.2019.12.002. Epub 2020 Jan 7. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31924477 |
| 2020 | Wilson JL, Nägele T, Linke M, Demel F, Fritsch SD, Mayr HK, Cai Z, Katholnig K, Sun X, Fragner L, Miller A, Haschemi A, Popa A, Bergthaler A, Hengstschläger M, Weichhart T, Weckwerth W. Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation. Cell Rep. 2020 Feb 4;30(5):1542-1552.e7. doi: 10.1016/j.celrep.2020.01.011. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32023468 |
| 2020 | Preglej T, Hamminger P, Luu M, Bulat T, Andersen L, Göschl L, Stolz V, Rica R, Sandner L, Waltenberger D, Tschismarov R, Faux T, Boenke T, Laiho A, Elo LL, Sakaguchi S, Steiner G, Decker T, Bohle B, Visekruna A, Bock C, Strobl B, Seiser C, Boucheron N, Ellmeier W. Histone deacetylases 1 and 2 restrain CD4+ cytotoxic T lymphocyte differentiation. JCI Insight. 2020 Feb 27;5(4):e133393. doi: 10.1172/jci.insight.133393. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32102981 |
| 2020 | Scherer M, Nebel A, Franke A, Walter J, Lengauer T, Bock C, Müller F, List M. Quantitative comparison of within-sample heterogeneity scores for DNA methylation data. Nucleic Acids Res. 2020 May 7;48(8):e46. doi: 10.1093/nar/gkaa120. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32103242 |
| 2020 | Fellinger P, Wolf P, Pfleger L, Krumpolec P, Krssak M, Klavins K, Wolfsberger S, Micko A, Carey P, Gürtl B, Vila G, Raber W, Fürnsinn C, Scherer T, Trattnig S, Kautzky-Willer A, Krebs M, Winhofer Y. Increased ATP synthesis might counteract hepatic lipid accumulation in acromegaly. JCI Insight. 2020 Mar 12;5(5):e134638. doi: 10.1172/jci.insight.134638. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32106111 |
| 2020 | Loregger A, Raaben M, Nieuwenhuis J, Tan JME, Jae LT, van den Hengel LG, Hendrix S, van den Berg M, Scheij S, Song JY, Huijbers IJ, Kroese LJ, Ottenhoff R, van Weeghel M, van de Sluis B, Brummelkamp T, Zelcer N. Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism. Nat Commun. 2020 Feb 28;11(1):1128. doi: 10.1038/s41467-020-14811-1. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32111832 |
| 2020 | Szymczak S, Dose J, Torres GG, Heinsen FA, Venkatesh G, Datlinger P, Nygaard M, Mengel-From J, Flachsbart F, Klapper W, Christensen K, Lieb W, Schreiber S, Häsler R, Bock C, Franke A, Nebel A. DNA methylation QTL analysis identifies new regulators of human longevity. Hum Mol Genet. 2020 May 8;29(7):1154-1167. doi: 10.1093/hmg/ddaa033. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32160291 |
| 2020 | Rosser EC, Piper CJM, Matei DE, Blair PA, Rendeiro AF, Orford M, Alber DG, Krausgruber T, Catalan D, Klein N, Manson JJ, Drozdov I, Bock C, Wedderburn LR, Eaton S, Mauri C. Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells. Cell Metab. 2020 Apr 7;31(4):837-851.e10. doi: 10.1016/j.cmet.2020.03.003. Epub 2020 Mar 25. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32213346 |
| 2020 | Ulz P, Perakis S, Zhou Q, Moser T, Belic J, Lazzeri I, Wölfler A, Zebisch A, Gerger A, Pristauz G, Petru E, White B, Roberts CES, John JS, Schimek MG, Geigl JB, Bauernhofer T, Sill H, Bock C, Heitzer E, Speicher MR. Publisher Correction: Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection. Nat Commun. 2020 Apr 20;11(1):1965. doi: 10.1038/s41467-020-15799-4. Erratum for: Nat Commun. 2019 Oct 11;10(1):4666. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32313081 |
| 2020 | Hainberger D, Stolz V, Zhu C, Schuster M, Müller L, Hamminger P, Rica R, Waltenberger D, Alteneder M, Krausgruber T, Hladik A, Knapp S, Bock C, Trauner M, Farrar MA, Ellmeier W. NCOR1 Orchestrates Transcriptional Landscapes and Effector Functions of CD4+ T Cells. Front Immunol. 2020 Apr 3;11:579. doi: 10.3389/fimmu.2020.00579. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32318068 |
| 2020 | Jaeger MG, Schwalb B, Mackowiak SD, Velychko T, Hanzl A, Imrichova H, Brand M, Agerer B, Chorn S, Nabet B, Ferguson FM, Müller AC, Bergthaler B, Gray NS, Bradner JB, Bock C, Hnisz D, Cramer P, Winter GE. Selective Mediator Dependence of Cell-Type-Specifying Transcription. Nat Genet. 2020 Jun 1. doi: 10.1038/s41588-020-0635-0. Online ahead of print. Abstract: https://pubmed.ncbi.nlm.nih.gov/32483291/ |
| 2020 | Lercher A, Baazim H, Bergthaler A. Systemic Immunometabolism: Challenges and Opportunities. Immunity. 2020 Sep 15;53(3):496-509. doi: 10.1016/j.immuni.2020.08.012. Abstract: https://pubmed.ncbi.nlm.nih.gov/32937151/ |
| 2020 | Lercher A, Popa AM, Viczenczova C, Kosack L, Klavins K, Agerer B, Opitz CA, Lanz TV, Platten M, Bergthaler A. Hepatocyte-intrinsic type I interferon signaling reprograms metabolism and reveals a novel compensatory mechanism of the tryptophan-kynurenine pathway in viral hepatitis. PLoS Pathog. 2020 Oct 12;16(10):e1008973. doi: 10.1371/journal.ppat.1008973. eCollection 2020 Oct. Abstract: https://pubmed.ncbi.nlm.nih.gov/33045014/ |
| 2020 | Krausgruber T, Fortelny N, Fife-Gernedl V, Senekowitsch M, Schuster LC, Lercher A, Nemc A, Schmidl C, Rendeiro AF, Bergthaler A, Bock C. Structural cells are key regulators of organ-specific immune responses. Nature. 2020 Jul;583(7815):296-302. doi: 10.1038/s41586-020-2424-4. Epub 2020 Jul 1. Abstract: https://pubmed.ncbi.nlm.nih.gov/32612232/ |
| 2020 | Hagelkruys A, Wirnsberger G, Stadlmann J, Wöhner M, Horrer M, Vilagos B, Jonsson G, Kogler M, Tortola L, Novatchkova M, Bönelt P, Hoffmann D, Koglgruber R, Steffen U, Schett G, Busslinger M, Bergthaler A, Klein C, Penninger JM. A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans. J Exp Med. 2021 Jan 4;218(1):e20200559. doi: 10.1084/jem.20200559. Abstract: https://pubmed.ncbi.nlm.nih.gov/32930709/ |
| 2020 | Liu GJ, Jaritz M, Wöhner M, Agerer B, Bergthaler A, Malin SG, Busslinger M. Repression of the B cell identity factor Pax5 is not required for plasma cell development. J Exp Med. 2020 Nov 2;217(11):e20200147. doi: 10.1084/jem.20200147. Abstract: https://pubmed.ncbi.nlm.nih.gov/32780801/ |
| 2020 | Ali OH, Bomze D, Risch L, Brugger SD, Paprotny M, Weber M, Thiel S, Kern L, Albrich WC, Kohler P, Kahlert CR, Vernazza P, Bühler PK, Schüpbach RA, Gómez-Mejia A, Popa AM, Bergthaler A, Penninger JM, Flatz L. Severe COVID-19 is associated with elevated serum IgA and antiphospholipid IgA-antibodies. Clin Infect Dis. 2020 Sep 30;ciaa1496. doi: 10.1093/cid/ciaa1496. Online ahead of print. Abstract: https://pubmed.ncbi.nlm.nih.gov/32997739/ |
| 2020 | Zoufaly A, Poglitsch M, Aberle JH, Hoepler W, Seitz T, Traugott M, Grieb A, Pawelka E, Laferl H, Wenisch C, Neuhold S, Haider D, Stiasny K, Bergthaler A, Puchhammer-Stoeckl E, Mirazimi A, Montserrat N, Zhang H, Slutsky AS, Penninger JM. Human recombinant soluble ACE2 in severe COVID-19. Lancet Respir Med. 2020 Nov;8(11):1154-1158. doi: 10.1016/S2213-2600(20)30418-5. Epub 2020 Sep 24. Abstract: https://pubmed.ncbi.nlm.nih.gov/33131609/ |
| 2020 | Schrottmaier WC , Salzmann M, Badrnya S, Mussbacher M, Kral-Pointner JB, Morava S, Pirabe A, Brunnthaler L, Yaiw KC, Heber UM, Pereyra D, Andersen JT, Bergthaler A, Söderberg-Nauclér C, Karlsson MCI, Assinger A, Forsell MNE. Platelets mediate serological memory to neutralize viruses in vitro and in vivo. Blood Adv. 2020 Aug 25;4(16):3971-3976. doi: 10.1182/bloodadvances.2020001786. Abstract: https://pubmed.ncbi.nlm.nih.gov/32841338/ |
| 2020 | Alm E, Broberg EK, Connor T, Hodcroft EB, Komissarov AB, Maurer-Stroh S, Melidou A, Neher RA, O'Toole A, Pereyaslov D, WHO European Region sequencing laboratories and GISAID EpiCoV group; WHO European Region sequencing laboratories and GISAID EpiCoV group*. Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020. Euro Surveill. 2020 Aug;25(32):2001410. doi: 10.2807/1560-7917.ES.2020.25.32.2001410. Abstract: https://pubmed.ncbi.nlm.nih.gov/32794443/ |
| 2020 | van den Hoogen B, Santoni A, Sciumé G, Bowie A, O'Farrelly C, O'Neill L, Anthonsen M, Pardali K, Young S, Bergthaler A, Manel N, Zahn R, Kikkert M, Snijder E, van Kuppeveld F, Fouchier R, Hiscott J. Immunometabolism pathways as the basis for innovative anti-viral strategies (INITIATE): A Marie Sklodowska-Curie innovative training network. Virus Res. 2020 Oct 2;287:198094. doi: 10.1016/j.virusres.2020.198094. Epub 2020 Jul 28. Abstract: https://pubmed.ncbi.nlm.nih.gov/32730781/ |
| 2020 | Wilson JL, Nägele T, Linke M, Demel F, Fritsch SD, Mayr HK, Cai Z, Katholnig K, Sun X, Fragner L, Miller A, Haschemi A, Popa A, Bergthaler A, Hengstschläger M, Weichhart T, Weckwerth W. Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation. Cell Rep. 2020 Feb 4;30(5):1542-1552.e7. doi: 10.1016/j.celrep.2020.01.011. Abstract: https://pubmed.ncbi.nlm.nih.gov/32023468/ |
| 2020 | Brunner JS, Vulliard L, Hofmann M, Kieler M, Lercher A, Vogel A, Russier M, Brüggenthies JB, Kerndl M, Saferding V, Niederreiter B, Junza A, Frauenstein A, Scholtysek C, Mikami Y, Klavins K, Krönke G, Bergthaler A, O'Shea JJ, Weichhart T, Meissner F, Smolen JS, Cheng P, Yanes O, Menche J, Murray PJ, Sharif O, Blüml S, Schabbauer G. Environmental arginine controls multinuclear giant cell metabolism and formation. Nat Commun. 2020 Jan 22;11(1):431. doi: 10.1038/s41467-020-14285-1. Abstract: https://pubmed.ncbi.nlm.nih.gov/31969567/ |
| 2020 | Kreidl P, Schmid D, Maritschnik S, Richter L, Borena W, Genger JW, Popa A, Penz T, Bock C, Bergthaler A, Allerberger F. Emergence of coronavirus disease 2019 (COVID-19) in Austria. Wien Klin Wochenschr. 2020 Aug 20;1-8. doi: 10.1007/s00508-020-01723-9. Online ahead of print. Abstract: https://pubmed.ncbi.nlm.nih.gov/32816114/ |