| Year | Paper |
|---|---|
| 2019 | Andergassen D, Muckenhuber M, Bammer PC, Kulinski TM, Theussl HC, Shimizu T,Penninger JM, Pauler FM, Hudson QJ. The Airn lncRNA does not require any DNAelements within its locus to silence distant imprinted genes. PLoS Genet. 2019Jul 22;15(7):e1008268. doi: 10.1371/journal.pgen.1008268. [Epub ahead of print] Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31329595 |
| 2019 | Asp J, Skov V, Bellosillo B, Kristensen T, Lippert E, Dicker F, Schwarz J,Wojtaszewska M, Palmqvist L, Akiki S, Aggerholm A, Tolstrup Andersen M, GirodonF, Kjær L, Oppliger Leibundgut E, Pancrazzi A, Vorland M, Andrikovics H,Kralovics R, Cassinat B, Coucelo M, Eftimov A, Haslam K, Kusec R, Link-LenczowskaD, Lodé L, Matiakowska K, Naguib D, Navaglia F, Novotny GW, Percy MJ, SudarikovA, Hermouet S, Pallisgaard N. International external quality assurance of JAK2V617F quantification. Ann Hematol. 2019 May;98(5):1111-1118. doi:10.1007/s00277-018-3570-8. Epub 2018 Dec 8. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30535576 |
| 2019 | Asslaber D, Wacht N, Leisch M, Qi Y, Maeding N, Hufnagl C, Jansko B, Zaborsky N, Villunger A, Hartmann TN, Greil R, Egle A. BIRC3 Expression Predicts CLL Progression and Defines Treatment Sensitivity via Enhanced NF-κB Nuclear Translocation. Clin Cancer Res. 2019 Mar 15;25(6):1901-1912. doi:10.1158/1078-0432.CCR-18-1548. Epub 2018 Nov 28. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30487125 |
| 2019 | Baazim H, Schweiger M, Moschinger M, Xu H, Scherer T, Popa A, Gallage S, AliA, Khamina K, Kosack L, Vilagos B, Smyth M, Lercher A, Friske J, Merkler D,Aderem A, Helbich TH, Heikenwälder M, Lang PA, Zechner R, Bergthaler A. CD8(+) T cells induce cachexia during chronic viral infection. Nat Immunol. 2019Jun;20(6):701-710. doi: 10.1038/s41590-019-0397-y. Epub 2019 May 20. PubMed PMID:31110314; Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31110314. |
| 2019 | Bagchi-Chakraborty J, Francis A, Bray T, Masters L, Tsiantoulas D, Nus M,Harrison J, Broekhuizen M, Leggat J, Clatworthy MR, Espéli M, Smith KGC, BinderCJ, Mallat Z, Sage AP. B Cell Fcγ Receptor IIb Modulates Atherosclerosis in Male and Female Mice by Controlling Adaptive Germinal Center and Innate B-1-Cell Responses. Arterioscler Thromb Vasc Biol. 2019 Jul;39(7):1379-1389. doi:10.1161/ATVBAHA.118.312272. Epub 2019 May 16. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31092015 |
| 2019 | Bier J, Rao G, Payne K, Brigden H, French E, Pelham SJ, Lau A, Lenthall H,Edwards ESJ, Smart JM, Cole TS, Choo S, Joshi AY, Abraham RS, O'Sullivan M, Boztug K, Meyts I, Gray PE, Berglund LJ, Hsu P, Wong M, Holland SM, NotarangeloLD, Uzel G, Ma CS, Brink R, Tangye SG, Deenick EK. Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4(+) T cells. JAllergy Clin Immunol. 2019 Jul;144(1):236-253. doi: 10.1016/j.jaci.2019.01.033.Epub 2019 Feb 6. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30738173 |
| 2019 | Bonelli M, Dalwigk K, Platzer A, Olmos Calvo I, Hayer S, Niederreiter B,Holinka J, Sevelda F, Pap T, Steiner G, Superti-Furga G, Smolen JS, Kiener HP,Karonitsch T. IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes : JAKinibs suppress the interferon response in RA-FLSs. Exp Mol Med. 2019 Jul 8;51(7):75. doi:10.1038/s12276-019-0267-6. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31285419 |
| 2019 | Brand M, Winter GE. Stick it to E3s. Nat Chem Biol. 2019 Jul;15(7):655-656.doi: 10.1038/s41589-019-0312-8. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31209352 |
| 2019 | Brand M, Jiang B, Bauer S, Donovan KA, Liang Y, Wang ES, Nowak RP, Yuan JC,Zhang T, Kwiatkowski N, Müller AC, Fischer ES, Gray NS, Winter GE.Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML.Cell Chem Biol. 2019 Feb 21;26(2):300-306.e9. doi:10.1016/j.chembiol.2018.11.006. Epub 2018 Dec 27. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30595531 |
| 2019 | Brand M, Winter GE. Locus-Specific Knock-In of a Degradable Tag for Target Validation Studies. Methods Mol Biol. 2019;1953:105-119. doi:10.1007/978-1-4939-9145-7_7. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30912018 |
| 2019 | Brandstetter B, Dalwigk K, Platzer A, Niederreiter B, Kartnig F, Fischer A,Vladimer GI, Byrne RA, Sevelda F, Holinka J, Pap T, Steiner G, Superti-Furga G,Smolen JS, Kiener HP, Karonitsch T. FOXO3 is involved in the tumor necrosis factor-driven inflammatory response in fibroblast-like synoviocytes. Lab Invest. 2019 May;99(5):648-658. doi: 10.1038/s41374-018-0184-7. Epub 2019 Jan 24. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30679758 |
| 2019 | Calzoni E, Platt CD, Keles S, Kuehn HS, Beaussant-Cohen S, Zhang Y, Pazmandi J, Lanzi G, Pala F, Tahiat A, Artac H, Heredia RJ, Dmytrus J, Reisli I, Uygun V, Uygun D, Bingol A, Basaran E, Djenouhat K, Benhalla N, Bendahmane C, Emiroglu M, Kirchhausen T, Pasham M, Jones J, Wallace JG, Zheng L, Boisson B, Porta F,Rosenzweig SD, Su H, Giliani S, Lenardo M, Geha RS, Boztug K, Chou J, NotarangeloLD. F-BAR domain only protein 1 (FCHO1) deficiency is a novel cause of combined immune deficiency in human subjects. J Allergy Clin Immunol. 2019Jun;143(6):2317-2321.e12. doi: 10.1016/j.jaci.2019.02.014. Epub 2019 Feb 26. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30822429 |
| 2019 | Edwards ESJ, Bier J, Cole TS, Wong M, Hsu P, Berglund LJ, Boztug K, Lau A,Gostick E, Price DA, O'Sullivan M, Meyts I, Choo S, Gray P, Holland SM, DeenickEK, Uzel G, Tangye SG. Activating PIK3CD mutations impair human cytotoxiclymphocyte differentiation and function and EBV immunity. J Allergy Clin Immunol.2019 Jan;143(1):276-291.e6. doi: 10.1016/j.jaci.2018.04.030. Epub 2018 May 22. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29800648 |
| 2019 | Farmer JR, Foldvari Z, Ujhazi B, De Ravin SS, Chen K, Bleesing JJH, SchuetzC, Al-Herz W, Abraham RS, Joshi AY, Costa-Carvalho BT, Buchbinder D, Booth C,Reiff A, Ferguson PJ, Aghamohammadi A, Abolhassani H, Puck JM, Adeli M, Cancrini C, Palma P, Bertaina A, Locatelli F, Di Matteo G, Geha RS, Kanariou MG,Lycopoulou L, Tzanoudaki M, Sleasman JW, Parikh S, Pinero G, Fischer BM, DbaiboG, Unal E, Patiroglu T, Karakukcu M, Al-Saad KK, Dilley MA, Pai SY, Dutmer CM,Gelfand EW, Geier CB, Eibl MM, Wolf HM, Henderson LA, Hazen MM, Bonfim C,Wolska-Kuśnierz B, Butte MJ, Hernandez JD, Nicholas SK, Stepensky P, ChandrakasanS, Miano M, Westermann-Clark E, Goda V, Kriván G, Holland SM, Fadugba O,Henrickson SE, Ozen A, Karakoc-Aydiner E, Baris S, Kiykim A, Bredius R, Hoeger B,Boztug K, Pashchenko O, Neven B, Moshous D, Villartay JP, Bousfiha AA, Hill HR,Notarangelo LD, Walter JE. Outcomes and Treatment Strategies for Autoimmunity and Hyperinflammation in Patients with RAG Deficiency. J Allergy Clin Immunol Pract. 2019 Jul - Aug;7(6):1970-1985.e4. doi: 10.1016/j.jaip.2019.02.038. Epub 2019 Mar 12. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30877075 |
| 2019 | Fauster A, Rebsamen M, Willmann KL, César-Razquin A, Girardi E, Bigenzahn JW,Schischlik F, Scorzoni S, Bruckner M, Konecka J, Hörmann K, Heinz LX, Boztug K,Superti-Furga G. Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking. Cell Death Differ. 2019Jun;26(6):1138-1155. doi: 10.1038/s41418-018-0192-6. Epub 2018 Sep 20. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30237509 |
| 2019 | Goncalves-Alves E, Saferding V, Schliehe C, Benson R, Kurowska-Stolarska M,Brunner JS, Puchner A, Podesser BK, Smolen JS, Redlich K, Bonelli M, Brewer J, Bergthaler A, Steiner G, Blüml S. MicroRNA-155 Controls T Helper Cell Activation During Viral Infection. Front Immunol. 2019 Jun 13;10:1367. doi:10.3389/fimmu.2019.01367. eCollection 2019. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31275315 |
| 2019 | Gruber M, Bozic I, Leshchiner I, Livitz D, Stevenson K, Rassenti L, RosebrockD, Taylor-Weiner A, Olive O, Goyetche R, Fernandes SM, Sun J, Stewart C, Wong A, Cibulskis C, Zhang W, Reiter JG, Gerold JM, Gribben JG, Rai KR, Keating MJ, BrownJR, Neuberg D, Kipps TJ, Nowak MA, Getz G, Wu CJ. Growth dynamics in naturally progressing chronic lymphocytic leukaemia. Nature. 2019 Jun;570(7762):474-479.doi: 10.1038/s41586-019-1252-x. Epub 2019 May 29. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31142838 |
| 2019 | Hacker K, Benke S, Agerer B, Scinicariello S, Budroni V, Versteeg GA. A repetitive acidic region contributes to the extremely rapid degradation of the cell-context essential protein TRIM52. Sci Rep. 2019 May 27;9(1):7901. doi:10.1038/s41598-019-44359-0. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31133683 |
| 2019 | Hamdane N, Jühling F, Crouchet E, El Saghire H, Thumann C, Oudot MA, BandieraS, Saviano A, Ponsolles C, Roca Suarez AA, Li S, Fujiwara N, Ono A, Davidson I,Bardeesy N, Schmidl C, Bock C, Schuster C, Lupberger J, Habersetzer F, Doffoël M,Piardi T, Sommacale D, Imamura M, Uchida T, Ohdan H, Aikata H, Chayama K,Boldanova T, Pessaux P, Fuchs BC, Hoshida Y, Zeisel MB, Duong FHT, Baumert TF. HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response. Gastroenterology. 2019 Jun;156(8):2313-2329.e7.doi: 10.1053/j.gastro.2019.02.038. Epub 2019 Mar 2. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30836093 |
| 2019 | Heijink AM, Talens F, Jae LT, van Gijn SE, Fehrmann RSN, Brummelkamp TR, van Vugt MATM. BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity. NatCommun. 2019 Jan 9;10(1):100. doi: 10.1038/s41467-018-07927-y. PubMed PMID:30626869; Abstract: https://www.ncbi.nlm.nih.gov/pubmed/6327059 |
| 2019 | Kanduri C, Bock C, Gundersen S, Hovig E, Sandve GK. Colocalization analysesof genomic elements: approaches, recommendations and challenges. Bioinformatics. 2019 May 1;35(9):1615-1624. doi: 10.1093/bioinformatics/bty835. PubMed PMID:30307532; Abstract: https://www.ncbi.nlm.nih.gov/pubmed/6499241 |
| 2019 | Ketelhuth DFJ, Lutgens E, Bäck M, Binder CJ, Van den Bossche J, Daniel C,Dumitriu IE, Hoefer I, Libby P, O'Neill L, Weber C, Evans PC. Immunometabolism and atherosclerosis: perspectives and clinical significance: a position paper from the Working Group on Atherosclerosis and Vascular Biology of the European Society of Cardiology. Cardiovasc Res. 2019 Jul 1;115(9):1385-1392. doi:10.1093/cvr/cvz166. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31228191 |
| 2019 | Kocacik Uygun DF, Uygun V, Daloğlu H, Öztürkmen S, Karasu G, Reisli İ, Sayar E, Yüksekkaya HA, Glocker EO, Boztuğ K, Yeşilipek A. Hematopoietic Stem Cell Transplantation From Unrelated Donors in 2 Cases of Interleukin-10 Receptor Deficiency: Is Surgery Not a Requirement? J Pediatr Hematol Oncol. 2019Jan;41(1):64-66. doi: 10.1097/MPH.0000000000001165. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29683948 |
| 2019 | Kosack L, Wingelhofer B, Popa A, Orlova A, Agerer B, Vilagos B, Majek P,Parapatics K, Lercher A, Ringler A, Klughammer J, Smyth M, Khamina K, Baazim H,de Araujo ED, Rosa DA, Park J, Tin G, Ahmar S, Gunning PT, Bock C, Siddle HV,Woods GM, Kubicek S, Murchison EP, Bennett KL, Moriggl R, Bergthaler A. The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease. Cancer Cell. 2019Jan 14;35(1):125-139.e9. doi: 10.1016/j.ccell.2018.11.018. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30645971 |
| 2019 | Lee NJ, Clarke IM, Zengin A, Enriquez RF, Nagy V, Penninger JM, Baldock PA,Herzog H. RANK deletion in neuropeptide Y neurones attenuates oestrogen deficiency-related bone loss. J Neuroendocrinol. 2019 Feb;31(2):e12687. doi:10.1111/jne.12687. Epub 2019 Feb 1. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30633834 |
| 2019 | Maurer B, Nivarthi H, Wingelhofer B, Pham HTT, Schlederer M, Suske T,Grausenburger R, Schiefer AI, Prchal-Murphy M, Chen D, Winkler S, Merkel O,Kornauth C, Hofbauer M, Hochgatterer B, Hoermann G, Hoelbl-Kovacic A, ProchazkovaJ, Lobello C, Cumaraswamy AA, Latzka J, Kitzwögerer M, Chott A, Janikova A,Pospíšilova Š, Loizou JI, Kubicek S, Valent P, Kolbe T, Grebien F, Kenner L,Gunning PT, Kralovics R, Herling M, Müller M, Rülicke T, Sexl V, Moriggl R. High activation of STAT5A drives peripheral T-cell lymphoma and leukemia.Haematologica. 2019 May 23. pii: haematol.2019.216986. doi:10.3324/haematol.2019.216986. [Epub ahead of print] Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31123029 |
| 2019 | Mayor-Ruiz C, Winter GE. Identification and characterization of cancer vulnerabilities via targeted protein degradation. Drug Discov Today Technol. 2019Apr;31:81-90. doi: 10.1016/j.ddtec.2018.12.003. Epub 2019 Jan 2. Review. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31200863. |
| 2019 | McAlpine CS, Kiss MG, Rattik S, He S, Vassalli A, Valet C, Anzai A, Chan CT, Mindur JE, Kahles F, Poller WC, Frodermann V, Fenn AM, Gregory AF, Halle L,Iwamoto Y, Hoyer FF, Binder CJ, Libby P, Tafti M, Scammell TE, Nahrendorf M,Swirski FK. Sleep modulates haematopoiesis and protects against atherosclerosis. Nature. 2019 Feb;566(7744):383-387. doi: 10.1038/s41586-019-0948-2. Epub 2019 Feb13. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30760925 |
| 2019 | Mezzadra R, de Bruijn M, Jae LT, Gomez-Eerland R, Duursma A, Scheeren FA,Brummelkamp TR, Schumacher TN. SLFN11 can sensitize tumor cells towards IFN-γ-mediated T cell killing. PLoS One. 2019 Feb 12;14(2):e0212053. doi:10.1371/journal.pone.0212053. eCollection 2019. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30753225 |
| 2019 | Mian AA, Baumann I, Liebermann M, Grebien F, Superti-Furga G, Ruthardt M,Ottmann OG, Hantschel O. The phosphatase UBASH3B/Sts-1 is a negative regulator of Bcr-Abl kinase activity and leukemogenesis. Leukemia. 2019 Apr 8. doi:10.1038/s41375-019-0468-y. [Epub ahead of print] Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30962580 |
| 2019 | Moik F, Riedl JM, Winder T, Terbuch A, Rossmann CH, Szkandera J, Bauernhofer T, Kasparek AK, Schaberl-Moser R, Reicher A, Prinz F, Pichler M, Stöger H, Stotz M, Gerger A, Posch F. Benefit of second-line systemic chemotherapy for advanced biliary tract cancer: A propensity score analysis. Sci Rep. 2019 Apr 3;9(1):5548.doi: 10.1038/s41598-019-42069-1. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30944390 |
| 2019 | Moskovskich A, Goldmann U, Kartnig F, Lindinger S, Konecka J, Fiume G,Girardi E, Superti-Furga G. The transporters SLC35A1 and SLC30A1 play opposite roles in cell survival upon VSV virus infection. Sci Rep. 2019 Jul 18;9(1):10471.doi: 10.1038/s41598-019-46952-9. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31320712 |
| 2019 | Müller F, Scherer M, Assenov Y, Lutsik P, Walter J, Lengauer T, Bock C. RnBeads 2.0: comprehensive analysis of DNA methylation data. Genome Biol. 2019Mar 14;20(1):55. doi: 10.1186/s13059-019-1664-9. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30871603 |
| 2019 | Nagy V, Hollstein R, Pai TP, Herde MK, Buphamalai P, Moeseneder P,Lenartowicz E, Kavirayani A, Korenke GC, Kozieradzki I, Nitsch R, Cicvaric A,Monje Quiroga FJ, Deardorff MA, Bedoukian EC, Li Y, Yigit G, Menche J, Perçin EF,Wollnik B, Henneberger C, Kaiser FJ, Penninger JM. HACE1 deficiency leads to structural and functional neurodevelopmental defects. Neurol Genet. 2019 Apr29;5(3):e330. doi: 10.1212/NXG.0000000000000330. eCollection 2019 Jun. PubMedPMID: 31321300; Abstract: https://www.ncbi.nlm.nih.gov/pubmed/6561753 |
| 2019 | Nieuwenhuis J, Brummelkamp TR. The Tubulin Detyrosination Cycle: Function andEnzymes. Trends Cell Biol. 2019 Jan;29(1):80-92. doi: 10.1016/j.tcb.2018.08.003. Epub 2018 Sep 10. Review. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30213517 |
| 2019 | Owusu M, Bannauer P, Ferreira da Silva J, Mourikis TP, Jones A, Májek P,Caldera M, Wiedner M, Lardeau CH, Mueller AC, Menche J, Kubicek S, Ciccarelli FD,Loizou JI. Mapping the Human Kinome in Response to DNA Damage. Cell Rep. 2019 Jan15;26(3):555-563.e6. doi: 10.1016/j.celrep.2018.12.087. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30650350 |
| 2019 | Patra V, Strobl J, Gruber-Wackernagel A, Vieyra-Garcia P, Stary G, Wolf P. CD11b(+) cells markedly express the itch cytokine interleukin-31 in polymorphic light eruption. Br J Dermatol. 2019 May 3. doi: 10.1111/bjd.18092. [Epub ahead ofprint] Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31049931 |
| 2019 | Pazmandi J, Kalinichenko A, Ardy RC, Boztug K. Early-onset inflammatory bowel disease as a model disease to identify key regulators of immune homeostasis mechanisms. Immunol Rev. 2019 Jan;287(1):162-185. doi: 10.1111/imr.12726. Review. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30565237 |
| 2019 | Pecquet C, Chachoua I, Roy A, Balligand T, Vertenoeil G, Leroy E, Albu RI,Defour JP, Nivarthi H, Hug E, Xu E, Ould-Amer Y, Mouton C, Colau D, Vertommen D, Shwe MM, Marty C, Plo I, Vainchenker W, Kralovics R, Constantinescu SN. Calreticulin mutants as oncogenic rogue chaperones for TpoR and traffic-defective pathogenic TpoR mutants. Blood. 2019 Jun 20;133(25):2669-2681. doi:10.1182/blood-2018-09-874578. Epub 2019 Mar 22. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30902807 |
| 2019 | Porsch F, Binder CJ. Impact of B-Cell-Targeted Therapies on Cardiovascular Disease. Arterioscler Thromb Vasc Biol. 2019 Jul 18:ATVBAHA119311996. doi:10.1161/ATVBAHA.119.311996. [Epub ahead of print] Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31315439 |
| 2019 | Puhm F, Afonyushkin T, Resch U, Obermayer G, Rohde M, Penz T, Schuster M,Wagner G, Rendeiro AF, Melki I, Kaun C, Wojta J, Bock C, Jilma B, Mackman N,Boilard E, Binder CJ. Mitochondria Are a Subset of Extracellular Vesicles Released by Activated Monocytes and Induce Type I IFN and TNF Responses in Endothelial Cells. Circ Res. 2019 Jun 21;125(1):43-52. doi:10.1161/CIRCRESAHA.118.314601. Epub 2019 May 8. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31219742 |
| 2019 | Rocamora-Reverte L, Tuzlak S, von Raffay L, Tisch M, Fiegl H, Drach M,Reichardt HM, Villunger A, Tischner D, Wiegers GJ. Glucocorticoid Receptor-Deficient Foxp3(+) Regulatory T Cells Fail to Control Experimental Inflammatory Bowel Disease. Front Immunol. 2019 Mar 18;10:472. doi:10.3389/fimmu.2019.00472. eCollection 2019. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30936873 |
| 2019 | Sage AP, Tsiantoulas D, Binder CJ, Mallat Z. The role of B cells inatherosclerosis. Nat Rev Cardiol. 2019 Mar;16(3):180-196. doi:10.1038/s41569-018-0106-9. Review. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30410107 |
| 2019 | Scalise M, Galluccio M, Pochini L, Cosco J, Trotta M, Rebsamen M,Superti-Furga G, Indiveri C. Insights into the transport side of the human SLC38A9 transceptor. Biochim Biophys Acta Biomembr. 2019 Jul 8;1861(9):1558-1567.doi: 10.1016/j.bbamem.2019.07.006. [Epub ahead of print] Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31295473 |
| 2019 | Schiefer AI, Salzer E, Füreder A, Szepfalusi Z, Müller-Sacherer T, Huber WD, Michel-Behnke I, Lawitschka A, Pichler H, Mann G, Hutter C, Simonitsch-Klupp I,Attarbaschi A. PD-L1 and PD1 expression in post-transplantation lymphoproliferative disease (PTLD) of childhood and adolescence: An inter- and intra-individual descriptive study covering the whole spectrum of PTLD categories. Cancer Med. 2019 Jul 3. doi: 10.1002/cam4.2394. [Epub ahead of print] Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31269329 |
| 2019 | Schischlik F, Jäger R, Rosebrock F, Hug E, Schuster M, Holly R, Fuchs E,Milosevic Feenstra JD, Bogner E, Gisslinger B, Schalling M, Rumi E, Pietra D,Fischer G, Faé I, Vulliard L, Menche J, Haferlach T, Meggendorfer M, Stengel A,Bock C, Cazzola M, Gisslinger H, Kralovics R. Mutational landscape of the transcriptome offers putative targets for immunotherapy of myeloproliferative neoplasms. Blood. 2019 Jul 11;134(2):199-210. doi: 10.1182/blood.2019000519. Epub2019 May 7. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31064751 |
| 2019 | Schmidl C, Vladimer GI, Rendeiro AF, Schnabl S, Krausgruber T, Taubert C,Krall N, Pemovska T, Araghi M, Snijder B, Hubmann R, Ringler A, Runggatscher K,Demirtas D, de la Fuente OL, Hilgarth M, Skrabs C, Porpaczy E, Gruber M, HoermannG, Kubicek S, Staber PB, Shehata M, Superti-Furga G, Jäger U, Bock C. Combined chemosensitivity and chromatin profiling prioritizes drug combinations in CLL. Nat Chem Biol. 2019 Mar;15(3):232-240. doi: 10.1038/s41589-018-0205-2. Epub 2019 Jan 28. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30692684 |
| 2019 | Schoeler K, Aufschnaiter A, Messner S, Derudder E, Herzog S, Villunger A,Rajewsky K, Labi V. TET enzymes control antibody production and shape the mutational landscape in germinal centre B cells. FEBS J. 2019 May 23. doi:10.1111/febs.14934. [Epub ahead of print] Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31120187 |
| 2019 | Schoeler K, Jakic B, Heppke J, Soratroi C, Aufschnaiter A, Hermann-Kleiter N,Villunger A, Labi V. CHK1 dosage in germinal center B cells controls humoral immunity. Cell Death Differ. 2019 Mar 20. doi: 10.1038/s41418-019-0318-5. [Epubahead of print] Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30894677 |
| 2019 | Sdelci S, Rendeiro AF, Rathert P, You W, Lin JG, Ringler A, Hofstätter G,Moll HP, Gürtl B, Farlik M, Schick S, Klepsch F, Oldach M, Buphamalai P,Schischlik F, Májek P, Parapatics K, Schmidl C, Schuster M, Penz T, Buckley DL,Hudecz O, Imre R, Wang SY, Maric HM, Kralovics R, Bennett KL, Müller AC, MechtlerK, Menche J, Bradner JE, Winter GE, Klavins K, Casanova E, Bock C, Zuber J,Kubicek S. MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation. Nat Genet. 2019 Jun;51(6):990-998. doi:10.1038/s41588-019-0413-z. Epub 2019 May 27. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31133746 |
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| 2019 | Chien J, Wolf FW, Grosche S, Yosef N, Garriga G, Mörck C. The Enigmatic Canal-Associated Neurons Regulate Caenorhabditis elegans Larval Development Through a cAMP Signaling Pathway. Genetics. 2019 Dec;213(4):1465-1478. doi: 10.1534/genetics.119.302628. Abstract: https://pubmed.ncbi.nlm.nih.gov/31619445/ |
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| 2019 | Conde CD, Petronczki ÖY, Baris S, Willmann KL, Girardi E, Salzer E, Weitzer S, Ardy RC, Krolo A, Ijspeert H, Kiykim A, Karakoc-Aydiner E, Förster-Waldl E, Kager L, Pickl WF, Superti-Furga G, Martínez J, Loizou JI, Ozen A, van der Burg M, Boztug K. Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress. J Clin Invest. 2019 Oct 1;129(10):4194-4206. doi: 10.1172/JCI128903. Abstract: https://pubmed.ncbi.nlm.nih.gov/31449058/ |
| 2019 | Connolly P, Garcia-Carpio I, Villunger A. Cell-Cycle Cross Talk with Caspases and Their Substrates. Cold Spring Harb Perspect Biol. 2019 Nov 14. pii: a036475. doi: 10.1101/cshperspect.a036475. Abstract: https://pubmed.ncbi.nlm.nih.gov/31727679/ |
| 2019 | Di Giacomo AM, Covre A, Finotello F, Rieder D, Danielli R, Sigalotti L, Giannarelli D, Petitprez F, Lacroix L, Valente M, Cutaia O, Fazio C, Amato G, Lazzeri A, Monterisi S, Miracco C, Coral S, Anichini A, Bock C, Nemc A, Oganesian A, Lowder J, Azab M, Fridman WH, Sautès-Fridman C, Trajanoski Z, Maio M. Guadecitabine Plus Ipilimumab in Unresectable Melanoma: The NIBIT-M4 Clinical Trial. Clin Cancer Res. 2019;25(24):7351–7362. doi:10.1158/1078-0432.CCR-19-1335 Abstract: https://pubmed.ncbi.nlm.nih.gov/31530631/ |
| 2019 | Doukas A, Karena E, Botou M, Papakostas K, Papadaki A, Tziouvara O, Xingi E, Frillingos S, Boleti H. Heterologous expression of the mammalian sodium-nucleobase transporter rSNBT1 in Leishmania tarentolae. Biochim Biophys Acta Biomembr. 2019 Sep 1;1861(9):1546-1557. doi: 10.1016/j.bbamem.2019.07.001. Abstract: https://pubmed.ncbi.nlm.nih.gov/31283918/ |
| 2019 | Downes K, Megy K, Duarte D, Vries M, Gebhart J, Hofer S, Shamardina O, Deevi SVV, Stephens J, Mapeta R, Tuna S, Al Hasso N, Besser MW, Cooper N, Daugherty L, Gleadall N, Greene D, Haimel M, Martin H, Papadia S, Revel-Vilk S, Sivapalaratnam S, Symington E, Thomas W, Thys C, Tolios A, Penkett CJ; NIHR BioResource, Ouwehand WH, Abbs S, Laffan MA, Turro E, Simeoni I, Mumford AD, Henskens YMC, Pabinger I, Gomez K, Freson K. Diagnostic high-throughput sequencing of 2396 patients with bleeding, thrombotic, and platelet disorders. Blood. 2019 Dec 5;134(23):2082-2091. doi: 10.1182/blood.2018891192. Abstract: https://pubmed.ncbi.nlm.nih.gov/31064749/ |
| 2019 | Ferreira da Silva J, Salic S, Wiedner M, Datlinger P, Essletzbichler P, Hanzl A, Superti-Furga G, Bock C, Winter G, Loizou JI. Genome-scale CRISPR screens are efficient in non-homologous end-joining deficient cells. Sci Rep. 2019 Oct 31;9(1):15751. doi: 10.1038/s41598-019-52078-9. Abstract: https://pubmed.ncbi.nlm.nih.gov/31673055/ |
| 2019 | Göschl L, Preglej T, Boucheron N, Saferding V, Müller L, Platzer A, Hirahara K, Shih H-Y, Backlund J, Matthias P, Niederreiter B, Hladik A, Kugler M, Gualdoni GA, Scheinecker C, Knapp S, Seiser C, Holmdahl R, Tillmann K, Plasenzotti R, Podesser B, Aletaha D, Smolen JS, Karonitsch T, Steiner G, Ellmeier W, Bonelli M. Histone deacetylase 1 (HDAC1): A key player of T cell-mediated arthritis. J Autoimmun. 2019;102379. doi:10.1016/j.jaut.2019.102379 Abstract: https://pubmed.ncbi.nlm.nih.gov/31883829/ |
| 2019 | Göschl L, Winkler S, Dmytrus J, Heredia RJ, Lagler H, Ramharter M, Scheinecker C, Bonelli M, Schmetterer K, Pickl WF, Grabmeier-Pfistershammer K, Hershfield MS, Boztug K, Förster-Waldl E, Gualdoni GA. Unreported Missense Mutation in the Dimerization Domain of ADA2 Leads to ADA2 Deficiency Associated with Severe Oral Ulcers and Neutropenia in a Female Somalian Patient-Addendum to the Genotype-Phenotype Puzzle. J Clin Immunol. 2019 Nov 4. doi: 10.1007/s10875-019-00700-w. Abstract: https://pubmed.ncbi.nlm.nih.gov/31686313/ |
| 2019 | Goyal G, Zheng J, Adam E, Steffes G, Jain M, Klavins K, Hummel T. Sphingolipid-dependent Dscam sorting regulates axon segregation. Nat Commun. 2019 Feb 18;10(1):813. doi: 10.1038/s41467-019-08765-2. Abstract: https://pubmed.ncbi.nlm.nih.gov/30778062/ |
| 2019 | Griss J, Bauer W, Wagner C, Simon M, Chen M, Grabmeier-Pfistershammer K, Maurer-Granofszky M, Roka F, Penz T, Bock C, Zhang G, Herlyn M, Glatz K, Läubli H, Mertz KD, Petzelbauer P, Wiesner T, Hartl M, Pickl WF, Somasundaram R, Steinberger P, Wagner SN. B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma. Nat Commun. 2019;10(1):4186. Published 2019 Sep 13. doi:10.1038/s41467-019-12160-2 Abstract: https://pubmed.ncbi.nlm.nih.gov/31519915/ |
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| 2019 | Halbritter F, Farlik M, Schwentner R, Jug G, Fortelny N, Schnöller T, Pisa H, Schuster LC, Reinprecht A, Czech T, Gojo J, Holter W, Minkov M, Bauer W, Simonitsch-Klupp I, Bock C, Hutter C. Epigenomics and Single-Cell Sequencing Define a Developmental Hierarchy in Langerhans Cell Histiocytosis. Cancer Discov. 2019 Oct;9(10):1406-1421. doi: 10.1158/2159-8290.CD-19-0138. Abstract: https://pubmed.ncbi.nlm.nih.gov/31345789/ |
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| 2019 | Katholnig K, Schütz B, Fritsch SD, Schörghofer D, Linke M, Sukhbaatar N, Matschinger JM, Unterleuthner D, Hirtl M, Lang M, Herac M, Spittler A, Bergthaler A, Schabbauer G, Bergmann M, Dolznig H, Hengstschläger M, Magnuson MA, Mikula M, Weichhart T. Inactivation of mTORC2 in macrophages is a signature of colorectal cancer that promotes tumorigenesis. JCI Insight. 2019;4(20):e124164. Published 2019 Oct 17. doi:10.1172/jci.insight.124164 Abstract: https://pubmed.ncbi.nlm.nih.gov/31619583/ |
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| 2019 | Korchynska S, Krassnitzer M, Malenczyk K, Prasad RB, Tretiakov EO, Rehman S, Cinquina V, Gernedl V, Farlik M, Petersen J, Hannes S, Schachenhofer J, Reisinger SN, Zambon A, Asplund O, Artner I, Keimpema E, Lubec G, Mulder J, Bock C, Pollak DD, Romanov RA, Pifl C, Groop L, Hökfelt TG, Harkany T. Life-long impairment of glucose homeostasis upon prenatal exposure to psychostimulants [published online ahead of print, 2019 Nov 21]. EMBO J. 2019;e100882. doi:10.15252/embj.2018100882 Abstract: https://pubmed.ncbi.nlm.nih.gov/31750562/ |
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| 2019 | Steinparzer I, Sedlyarov V, Rubin JD, Eislmayr K, Galbraith MD, Levandowski CB, Vcelkova T, Sneezum L, Wascher F, Amman F, Kleinova R, Bender H, Andrysik Z, Espinosa JM, Superti-Furga G, Dowell RD, Taatjes DJ, Kovarik P. Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions. Mol Cell. 2019 Nov 7;76(3):485-499.e8. doi: 10.1016/j.molcel.2019.07.034. Abstract: https://pubmed.ncbi.nlm.nih.gov/31495563/ |
| 2019 | Tesch VK, Abolhassani H, Shadur B, Zobel J, Mareika Y, Sharapova S, Karakoc-Aydiner E, Rivière JG, Garcia-Prat M, Moes N, Haerynck F, Gonzales-Granado LI, Santos Pérez JL, Mukhina A, Shcherbina A, Aghamohammadi A, Hammarström L, Dogu F, Haskologlu S, İkincioğulları AI, Bal SK, Baris S, Kilic SS, Karaca NE, Kutukculer N, Girschick H, Kolios A, Keles S, Uygun V, Stepensky P, Worth A, van Montfrans JM, Peters AMJ, Meyts I, Adeli M, Marzollo A, Padem N, Khojah AM, Chavoshzadeh Z, Stefanija MA, Bakhtiar S, Florkin B, Meeths M, Gamez L, Grimbacher B, Seppänen MR, Lankester A, Gennery AR, Seidel MG; Inborn Errors, Clinical, and Registry Working Parties of the European Society for Blood and Marrow Transplantation (EBMT) and the European Society of Immunodeficiencies (ESID). Long-term outcome of LRBA deficiency in 76 patients after various treatment modalities as evaluated by the immune deficiency and dysregulation activity (IDDA) score. J Allergy Clin Immunol. 2019 Dec 27. pii: S0091-6749(19)32603-X. doi: 10.1016/j.jaci.2019.12.896. Abstract: https://pubmed.ncbi.nlm.nih.gov/31887391/ |
| 2019 | Ulz P, Perakis S, Zhou Q, Moser T, Belic J, Lazzeri I, Wölfler A, Zebisch A, Gerger A, Pristauz G, Petru E, White B, Roberts CES, John JS, Schimek MG, Geigl JB, Bauernhofer T, Sill H, Bock C, Heitzer E, Speicher MR. Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection. Nat Commun. 2019;10(1):4666. Published 2019 Oct 11. doi:10.1038/s41467-019-12714-4 Abstract: https://pubmed.ncbi.nlm.nih.gov/31604930/ |
| 2019 | Unterhauser K, Pöltl L, Schneditz G, Kienesberger S, Glabonjat RA, Kitsera M, Pletz J, Josa-Prado F, Dornisch E, Lembacher-Fadum C, Roier S, Gorkiewicz G, Lucena D, Barasoain I, Kroutil W, Wiedner M, Loizou JI, Breinbauer R, Díaz JF, Schild S, Högenauer C, Zechner EL. Klebsiella oxytoca enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities. Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3774-3783. doi: 10.1073/pnas.1819154116. Abstract: https://pubmed.ncbi.nlm.nih.gov/30808763/ |
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| 2019 | Valent P, Orazi A, Savona MR, Patnaik MM, Onida F, van de Loosdrecht AA, Haase D, Haferlach T, Elena C, Pleyer L, Kern W, Pemovska T, Vladimer GI, Schanz J, Keller A, Lübbert M, Lion T, Sotlar K, Reiter A, De Witte T, Pfeilstöcker M, Geissler K, Padron E, Deininger M, Orfao A, Horny HP, Greenberg PL, Arber DA, Malcovati L, Bennett JM. Proposed diagnostic criteria for classical chronic myelomonocytic leukemia (CMML), CMML variants and pre-CMML conditions. Haematologica. 2019 Oct;104(10):1935-1949. doi: 10.3324/haematol.2019.222059. Abstract: https://pubmed.ncbi.nlm.nih.gov/31048353/ |
| 2019 | Yi G, Wierenga ATJ, Petraglia F, Narang P, Janssen-Megens EM, Mandoli A, Merkel A, Berentsen K, Kim B, Matarese F, Singh AA, Habibi E, Prange KHM, Mulder AB, Jansen JH, Clarke L, Heath S, van der Reijden BA, Flicek P, Yaspo ML, Gut I, Bock C, Schuringa JJ, Altucci L, Vellenga E, Stunnenberg HG, Martens JHA. Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes. Cell Rep. 2019;26(4):1059–1069.e6. doi:10.1016/j.celrep.2018.12.098 Abstract: https://pubmed.ncbi.nlm.nih.gov/30673601/ |
| 2019 | Rao S, Mondragón L, Pranjic B, Hanada T, Stoll G, Köcher T, Zhang P, Jais A, Lercher A, Bergthaler A, Schramek D, Haigh K, Sica V, Leduc M, Modjtahedi N, Pai TP, Onji M, Uribesalgo I, Hanada R, Kozieradzki I, Koglgruber R, Cronin SJ, She Z, Quehenberger F, Popper H, Kenner L, Haigh JJ, Kepp O, Rak M, Cai K, Kroemer G, Penninger JM. AIF-regulated oxidative phosphorylation supports lung cancer development. Cell Res. 2019 Jul;29(7):579-591. doi: 10.1038/s41422-019-0181-4. Epub 2019 May 27. Abstract: https://pubmed.ncbi.nlm.nih.gov/31133695/ |