Year | Paper |
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2011 | Barlow DP. Genomic imprinting: a mammalian epigenetic discovery model. Annu Rev Genet. 2011;45:379-403. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21942369 |
2011 | Bennett KL, Funk M, Tschernutter M, Breitwieser FP, Planyavsky M, Ubaida Mohien C, Muller A, Trajanoski Z, Colinge J, Superti-Furga G, Schmidt-Erfurth U. Proteomic analysis of human cataract aqueous humour: Comparison of one-dimensional gel LCMS with two-dimensional LCMS of unlabelled and iTRAQ(R)-labelled specimens. J Proteomics. 2011 Feb 1;74(2):151-66. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20940065 |
2011 | Binder CJ, Witztum JL. Is atherosclerosis an allergic disease? Circ Res. 2011 Oct 28;109(10):1103-4. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22034478 |
2011 | Bousquet J, Anto JM, Sterk PJ, Adcock IM, Chung KF, Roca J, Agusti A, Brightling C, Cambon-Thomsen A, Cesario A, Abdelhak S, Antonarakis SE, Avignon A, Ballabio A, Baraldi E, Baranov A, Bieber T, Bockaert J, Brahmachari S, Brambilla C, Bringer J, Dauzat M, Ernberg I, Fabbri L, Froguel P, Galas D, Gojobori T, Hunter P, Jorgensen C, Kauffmann F, Kourilsky P, Kowalski ML, Lancet D, Pen CL, Mallet J, Mayosi B, Mercier J, Metspalu A, Nadeau JH, Ninot G, Noble D, Ozturk M, Palkonen S, Prefaut C, Rabe K, Renard E, Roberts RG, Samolinski B, Schunemann HJ, Simon HU, Soares MB, Superti-Furga G, Tegner J, Verjovski- Almeida S, Wellstead P, Wolkenhauer O, Wouters E, Balling R, Brookes AJ, Charron D, Pison C, Chen Z, Hood L, Auffray C. Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Med. 2011;3(7):43. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21745417 |
2011 | Boztug K, Rosenberg PS, Dorda M, Banka S, Moulton T, Curtin J, Rezaei N, Corns J, Innis JW, Avci Z, Tran HC, Pellier I, Pierani P, Fruge R, Parvaneh N, Mamishi S, Mody R, Darbyshire P, Motwani J, Murray J, Buchanan GR, Newman WG, Alter BP, Boxer LA, Donadieu J, Welte K, Klein C. Extended Spectrum of Human Glucose-6-Phosphatase Catalytic Subunit 3 Deficiency: Novel Genotypes and Phenotypic Variability in Severe Congenital Neutropenia. J Pediatr. 2011 Nov 1. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22050868 |
2011 | Breitwieser FP, Muller A, Dayon L, Kocher T, Hainard A, Pichler P, Schmidt- Erfurth U, Superti- Furga G, Sanchez JC, Mechtler K, Bennett KL, Colinge J. General statistical modeling of data from protein relative expression isobaric tags. J Proteome Res. 2011 Jun 3;10(6):2758-66. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21526793 |
2011 | Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Burckstummer T, Bennett KL, Superti-Furga G, Colinge J. Initial characterization of the human central proteome. BMC Syst Biol. 2011;5:17. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21269460 |
2011 | Carette JE, Guimaraes CP, Wuethrich I, Blomen VA, Varadarajan M, Sun C, Bell G, Yuan B, Muellner MK, Nijman SM, Ploegh HL, Brummelkamp TR. Global gene disruption in human cells to assign genes to phenotypes by deep sequencing. Nat Biotechnol. 2011 Jun;29(6):542-6. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21623355 |
2011 | Carillo S, Henry L, Lippert E, Girodon F, Guiraud I, Richard C, Dubois Galopin F, Cleyrat C, Jourdan E, Kralovics R, Hermouet S, Lavabre-Bertrand T. Nested high-resolution melting curve analysis a highly sensitive, reliable, and simple method for detection of JAK2 exon 12 mutations – clinical relevance in the monitoring of polycythemia. J Mol Diagn. 2011 May;13(3):263-70. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21497288 |
2011 | Gleixner KV, Mayerhofer M, Cerny-Reiterer S, Hormann G, Rix U, Bennett KL, Hadzijusufovic E, Meyer RA, Pickl WF, Gotlib J, Horny HP, Reiter A, Mitterbauer-Hohendanner G, Superti-Furga G, Valent P. KIT-D816V-independent oncogenic signaling in neoplastic cells in systemic mastocytosis: role of Lyn and Btk activation and disruption by dasatinib and bosutinib. Blood. 2011 Aug 18;118(7):1885-98. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21680801 |
2011 | Goncalves A, Burckstummer T, Dixit E, Scheicher R, Gorna MW, Karayel E, Sugar C, Stukalov A, Berg T, Kralovics R, Planyavsky M, Bennett KL, Colinge J, Superti-Furga G. Functional dissection of the TBK1 molecular network. PLoS One. 2011;6(9):e23971. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21931631 |
2011 | Gratz N, Hartweger H, Matt U, Kratochvill F, Janos M, Sigel S, Drobits B, Li XD, Knapp S, Kovarik P. Type I interferon production induced by Streptococcus pyogenes-derived nucleic acids is required for host protection. PLoS Pathog. 2011 May;7(5):e1001345. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21625574 |
2011 | Grebien F, Hantschel O, Wojcik J, Kaupe I, Kovacic B, Wyrzucki AM, Gish GD, Cerny-Reiterer S, Koide A, Beug H, Pawson T, Valent P, Koide S, Superti-Furga G. Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis. Cell. 2011 Oct 14;147(2):306-19. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22000011 |
2011 | Haider L, Fischer MT, Frischer JM, Bauer J, Hoftberger R, Botond G, Esterbauer H, Binder CJ, Witztum JL, Lassmann H. Oxidative damage in multiple sclerosis lesions. Brain. 2011 Jul;134(Pt 7):1914-24. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21653539 |
2011 | Hantschel O, Grebien F, Superti-Furga G. Targeting allosteric regulatory modules in oncoproteins: “drugging the undruggable”. Oncotarget. 2011 Nov;2(11):828-9. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22084171 |
2011 | Harutyunyan A, Gisslinger B, Klampfl T, Berg T, Bagienski K, Gisslinger H, Kralovics R. Rare germline variants in regions of loss of heterozygosity may influence clinical course of hematological malignancies. Leukemia. 2011 Nov;25(11):1782-4. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21681190 |
2011 | Harutyunyan A, Klampfl T, Cazzola M, Kralovics R. p53 lesions in leukemic transformation. N Engl J Med. 2011 Feb 3;364(5):488-90. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21288114 |
2011 | Haura EB, Muller A, Breitwieser FP, Li J, Grebien F, Colinge J, Bennett KL. Using iTRAQ combined with tandem affinity purification to enhance low-abundance proteins associated with somatically mutated EGFR core complexes in lung cancer. J Proteome Res. 2011 Jan 7;10(1):182-90. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20945942 |
2011 | Hayee B, Antonopoulos A, Murphy EJ, Rahman FZ, Sewell G, Smith BN, McCartney S, Furman M, Hall G, Bloom SL, Haslam SM, Morris HR, Boztug K, Klein C, Winchester B, Pick E, Linch DC, Gale RE, Smith AM, Dell A, Segal AW. G6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunction. Glycobiology. 2011 Jul;21(7):914-24. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21385794 |
2011 | Hoermann G, Cerny-Reiterer S, Perne A, Klauser M, Hoetzenecker K, Klein K, Mullauer L, Groger M, Nijman SM, Klepetko W, Valent P, Mayerhofer M. Identification of oncostatin M as a STAT5-dependent mediator of bone marrow remodeling in KIT D816V-positive systemic mastocytosis. Am J Pathol. 2011 May;178(5):2344-56. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21457934 |
2011 | Huang R, Jaritz M, Guenzl P, Vlatkovic I, Sommer A, Tamir IM, Marks H, Klampfl T, Kralovics R, Stunnenberg HG, Barlow DP, Pauler FM. An RNA-Seq strategy to detect the complete coding and non-coding transcriptome including full-length imprinted macro ncRNAs. PLoS One. 2011;6(11):e27288. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22102886 |
2011 | Huber K, Superti-Furga G. After the grape rush: sirtuins as epigenetic drug targets in neurodegenerative disorders. Bioorg Med Chem. 2011 Jun 15;19(12):3616-24. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21306906 |
2011 | Hudson QJ, Seidl CI, Kulinski TM, Huang R, Warczok KE, Bittner R, Bartolomei MS, Barlow DP. Extra-embryonic-specific imprinted expression is restricted to defined lineages in the post-implantation embryo. Dev Biol. 2011 May 15;353(2):420-31. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21354127 |
2011 | Jager R, Kralovics R. Molecular pathogenesis of Philadelphia chromosome negative chronic myeloproliferative neoplasms. Curr Cancer Drug Targets. 2011 Jan;11(1):20-30. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21062246 |
2011 | Klampfl T, Harutyunyan A, Berg T, Gisslinger B, Schalling M, Bagienski K, Olcaydu D, Passamonti F, Rumi E, Pietra D, Jager R, Pieri L, Guglielmelli P, Iacobucci I, Martinelli G, Cazzola M, Vannucchi AM, Gisslinger H, Kralovics R. Genome integrity of myeloproliferative neoplasms in chronic phase and during disease progression. Blood. 2011 Jul 7;118(1):167-76. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21531982 |
2011 | Luo X, Liu Y, Kubicek S, Myllyharju J, Tumber A, Ng S, Che KH, Podoll J, Heightman TD, Oppermann U, Schreiber SL, Wang X. A selective inhibitor and probe of the cellular functions of Jumonji C domain-containing histone demethylases. J Am Chem Soc. 2011 Jun 22;133(24):9451-6. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21585201 |
2011 | Lutgens E, Binder CJ. Immunology of atherosclerosis. Thromb Haemost. 2011 Nov;106(5):755-6. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22011700 |
2011 | Miller YI, Choi SH, Wiesner P, Fang L, Harkewicz R, Hartvigsen K, Boullier A, Gonen A, Diehl CJ, Que X, Montano E, Shaw PX, Tsimikas S, Binder CJ, Witztum JL. Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity. Circ Res. 2011 Jan 21;108(2):235-48. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21252151 |
2011 | Muellner MK, Uras IZ, Gapp BV, Kerzendorfer C, Smida M, Lechtermann H, Craig-Mueller N, Colinge J, Duernberger G, Nijman SM. A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer. Nat Chem Biol. 2011 Nov;7(11):787-93. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21946274 |
2011 | Nijman SM. Synthetic lethality: general principles, utility and detection using genetic screens in human cells. FEBS Lett. 2011 Jan 3;585(1):1-6. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21094158 |
2011 | Olcaydu D, Rumi E, Harutyunyan A, Passamonti F, Pietra D, Pascutto C, Berg T, Jager R, Hammond E, Cazzola M, Kralovics R. The role of the JAK2 GGCC haplotype and the TET2 gene in familial myeloproliferative neoplasms. Haematologica. 2011 Mar;96(3):367-74. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21173100 |
2011 | Pichlmair A, Lassnig C, Eberle CA, Gorna MW, Baumann CL, Burkard TR, Burckstummer T, Stefanovic A, Krieger S, Bennett KL, Rulicke T, Weber F, Colinge J, Muller M, Superti-Furga G. IFIT1 is an antiviral protein that recognizes 5’-triphosphate RNA. Nat Immunol. 2011 Jul;12(7):624-30. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21642987 |
2011 | Rumi E, Harutyunyan A, Elena C, Pietra D, Klampfl T, Bagienski K, Berg T, Casetti I, Pascutto C, Passamonti F, Kralovics R, Cazzola M. Identification of genomic aberrations associated with disease transformation by means of highresolution SNP array analysis in patients with myeloproliferative neoplasm. Am J Hematol. 2011 Dec;86(12): 974-9. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21953568 |
2011 | Santoro F, Barlow DP. Developmental control of imprinted expression by macro non-coding RNAs. Semin Cell Dev Biol. 2011 Jun;22(4):328-35. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21333747 |
2011 | Schneller D, Machat G, Sousek A, Proell V, van Zijl F, Zulehner G, Huber H, Mair M, Muellner MK, Nijman SM, Eferl R, Moriggl R, Mikulits W. p19(ARF) /p14(ARF) controls oncogenic functions of signal transducer and activator of transcription 3 in hepatocellular carcinoma. Hepatology. 2011 Jul;54(1):164-72. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21452288 |
2011 | Vilaine M, Olcaydu D, Harutyunyan A, Bergeman J, Tiab M, Ramee JF, Chen JM, Kralovics R, Hermouet S. Homologous recombination of wild-type JAK2, a novel early step in the development of myeloproliferative neoplasm. Blood. 2011 Dec 8;118(24):6468-70. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22161852 |
2011 | Weber C, Meiler S, Doring Y, Koch M, Drechsler M, Megens RT, Rowinska Z, Bidzhekov K, Fecher C, Ribechini E, van Zandvoort MA, Binder CJ, Jelinek I, Hristov M, Boon L, Jung S, Korn T, Lutz MB, Forster I, Zenke M, Hieronymus T, Junt T, Zernecke A. CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice. J Clin Invest. 2011 Jul;121(7):2898-910. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21633167 |
2011 | Weismann D, Hartvigsen K, Lauer N, Bennett KL, Scholl HP, Charbel Issa P, Cano M, Brandstatter H, Tsimikas S, Skerka C, Superti-Furga G, Handa JT, Zipfel PF, Witztum JL, Binder CJ. Complement factor H binds malondialdehyde epitopes and protects from oxidative stress. Nature. 2011 Oct 6;478(7367):76-81. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21979047 |
2011 | Winter GE, Rix U, Lissat A, Stukalov A, Mullner MK, Bennett KL, Colinge J, Nijman SM, Kubicek S, Kovar H, Kontny U, Superti-Furga G. An integrated chemical biology approach identifies specific vulnerability of Ewing’s sarcoma to combined inhibition of Aurora kinases A and B. Mol Cancer Ther. 2011 Oct;10(10):1846-56. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21768330 |
2011 | Wool GD, Cabana VG, Lukens J, Shaw PX, Binder CJ, Witztum JL, Reardon CA, Getz GS. 4F Peptide reduces nascent atherosclerosis and induces natural antibody production in apolipoprotein E-null mice. FASEB J. 2011 Jan;25(1):290-300. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20876212 |
2011 | Zimprich A, Benet-Pages A, Struhal W, Graf E, Eck SH, Offman MN, Haubenberger D, Spielberger S, Schulte EC, Lichtner P, Rossle SC, Klopp N, Wolf E, Seppi K, Pirker W, Presslauer S, Mollenhauer B, Katzenschlager R, Foki T, Hotzy C, Reinthaler E, Harutyunyan A, Kralovics R, Peters A, Zimprich F, Brucke T, Poewe W, Auff E, Trenkwalder C, Rost B, Ransmayr G, Winkelmann J, Meitinger T, Strom TM. A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease. Am J Hum Genet. 2011 Jul 15;89(1):168-75. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21763483 |
2011 | Zivkovic A, Sharif O, Stich K, Doninger B, Biaggio M, Colinge J, Bilban M, Mesteri I, Hazemi P, Lemmens-Gruber R, Knapp S. TLR 2 and CD14 mediate innate immunity and lung inflammation to staphylococcal Panton-Valentine leukocidin in vivo. J Immunol. 2011 Feb 1;186(3):1608-17. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21178007 |