Groups

YearPaper
2019 Brand M, Winter GE. Stick it to E3s. Nat Chem Biol. 2019 Jul;15(7):655-656.doi: 10.1038/s41589-019-0312-8.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31209352
2019 Brand M, Jiang B, Bauer S, Donovan KA, Liang Y, Wang ES, Nowak RP, Yuan JC,Zhang T, Kwiatkowski N, Müller AC, Fischer ES, Gray NS, Winter GE.Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML.Cell Chem Biol. 2019 Feb 21;26(2):300-306.e9. doi:10.1016/j.chembiol.2018.11.006. Epub 2018 Dec 27.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30595531
2019 Brand M, Winter GE. Locus-Specific Knock-In of a Degradable Tag for TargetValidation Studies. Methods Mol Biol. 2019;1953:105-119. doi:10.1007/978-1-4939-9145-7_7.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30912018
2019 Mayor-Ruiz C, Winter GE. Identification and characterization of cancervulnerabilities via targeted protein degradation. Drug Discov Today Technol. 2019Apr;31:81-90. doi: 10.1016/j.ddtec.2018.12.003. Epub 2019 Jan 2. Review.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31200863.
2019 Sdelci S, Rendeiro AF, Rathert P, You W, Lin JG, Ringler A, Hofstätter G,Moll HP, Gürtl B, Farlik M, Schick S, Klepsch F, Oldach M, Buphamalai P,Schischlik F, Májek P, Parapatics K, Schmidl C, Schuster M, Penz T, Buckley DL,Hudecz O, Imre R, Wang SY, Maric HM, Kralovics R, Bennett KL, Müller AC, MechtlerK, Menche J, Bradner JE, Winter GE, Klavins K, Casanova E, Bock C, Zuber J,Kubicek S. MTHFD1 interaction with BRD4 links folate metabolism totranscriptional regulation. Nat Genet. 2019 Jun;51(6):990-998. doi:10.1038/s41588-019-0413-z. Epub 2019 May 27.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31133746
2019 Mayor-Ruiz C, Jaeger MG, Bauer S, Brand M, Sin C, Hanzl A, Mueller AC, Menche J, Winter GE. Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation. Mol Cell. 2019 Aug 22;75(4):849-858.e8. doi: 10.1016/j.molcel.2019.07.013.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31442425