Publications

Groups

Year

Paper

2025

Ticks' tricks: immunomodulatory effects of ixodid tick saliva at the cutaneous tick-host interface
Lisa Kleissl, Sophie Weninger, Florian Winkler, Margarida Ruivo, Michiel Wijnveld, Johanna Strobl.
Front Immunol. 2025 Mar 27;16:1520665. doi: 10.3389/fimmu.2025.1520665. eCollection 2025.
Abstract: https://pubmed.ncbi.nlm.nih.gov/40213541/

2025

The polyamine-regulating enzyme SSAT1 impairs tissue regulatory T cell function in chronic cutaneous inflammation
Teresa Neuwirth, Daniel Malzl, Katja Knapp, Panagiota Tsokkou, Lisa Kleissl, Anna Gabriel, Baerbel Reininger, Christian Freystätter, Nara Marella, Ana P Kutschat, Elisabeth Ponweiser, Arvand Haschemi, Davide Seruggia, Jörg Menche, Erwin F Wagner, Georg Stary.
Immunity. 2025 Mar 11;58(3):632-647.e12. doi: 10.1016/j.immuni.2025.02.011. Epub 2025 Feb 28.
Abstract: https://pubmed.ncbi.nlm.nih.gov/40023161/

2024

Mast cell-derived BH4 and serotonin are critical mediators of postoperative pain
Philipp Starkl, Gustav Jonsson, Tyler Artner, Bruna Lenfers Turnes, Laura-Marie Gail, Tiago Oliveira, Aakanksha Jain, Nadine Serhan, Karel Stejskal, Karin Lakovits, Anastasiya Hladik, Meilin An, Keith M Channon, Hail Kim, Thomas Köcher, Wolfgang Weninger, Georg Stary, Sylvia Knapp, Victoria Klang, Nicolas Gaudenzio, Clifford J Woolf, Shweta Tikoo, Rohit Jain, Josef M Penninger, Shane J F Cronin.
Sci Immunol. 2024 Aug 23;9(98):eadh0545. doi: 10.1126/sciimmunol.adh0545. Epub 2024 Aug 23.
Abstract: https://pubmed.ncbi.nlm.nih.gov/39178277/

2024

Dysfunctional tumor-infiltrating Vδ1 + T lymphocytes in microsatellite-stable colorectal cancer
Victoria Stary, Ram V Pandey, Julia List, Lisa Kleissl, Florian Deckert, Julijan Kabiljo, Johannes Laengle, Vasileios Gerakopoulos, Rudolf Oehler, Lukas Watzke, Matthias Farlik, Samuel W Lukowski, Anne B Vogt, Georg Stary, Hannes Stockinger, Michael Bergmann, Nina Pilat.
Nat Commun. 2024 Aug 13;15(1):6949. doi: 10.1038/s41467-024-51025-1.
Abstract: https://pubmed.ncbi.nlm.nih.gov/39138181/

2024

Combination of compound screening with an animal model identifies pentamidine to prevent Chlamydia trachomatis infection
Katja Knapp, Romana Klasinc, Anna Koren, Magdalena Siller, Ruth Dingelmaier-Hovorka, Mathias Drach, Juan Sanchez, David Chromy, Marlene Kranawetter, Christoph Grimm, Andreas Bergthaler, Stefan Kubicek, Hannes Stockinger, Georg Stary.
Cell Rep Med. 2024 Jul 16;5(7):101643. doi: 10.1016/j.xcrm.2024.101643. Epub 2024 Jul 8.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38981484/

2024

Beyond the microscope: Unveiling bacterial vaginosis with AI-powered multiomics data analysis
Simona Saluzzo, Georg Stary.
J Eur Acad Dermatol Venereol. 2024 Jun;38(6):999-1000. doi: 10.1111/jdv.20022.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38794929/

2024

Expanding strategies to resolve psoriasis-like inflammation: Non-canonical NF-κB signaling controls IL-23 production in dendritic cells
Teresa Neuwirth, Georg Stary.
Mol Ther. 2024 May 1;32(5):1195-1196. doi: 10.1016/j.ymthe.2024.04.012. Epub 2024 Apr 17.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38631353/

2024

Aberrant Lipid Metabolism in Macrophages Is Associated with Granuloma Formation in Sarcoidosis
Clarice X Lim, Anna Redl, Lisa Kleissl, Ram Vinay Pandey, Carolina Mayerhofer, Thomas El Jammal, Mario Mazic, Karine Gonzales, Nyamdelger Sukhbaatar, Thomas Krausgruber, Christoph Bock, Markus Hengstschläger, Alain Calender, Yves Pacheco, Georg Stary, Thomas Weichhart.
Am J Respir Crit Care Med. 2024 May 1;209(9):1152-1164. doi: 10.1164/rccm.202307-1273OC.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38353578/

2024

Efficacy and safety of mTOR inhibition in cutaneous sarcoidosis: a single-centre trial
Anna Redl, Konstantin Doberer, Luisa Unterluggauer, Lisa Kleissl, Christoph Krall, Carolina Mayerhofer, Bärbel Reininger, Victoria Stary, Nina Zila, Wolfgang Weninger, Thomas Weichhart, Christoph Bock, Thomas Krausgruber, Georg Stary.
Lancet Rheumatol. 2024 Feb;6(2):e81-e91. doi: 10.1016/S2665-9913(23)00302-8.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38267106/

2023

Cohesin and CTCF do not assemble TADs in Xenopus sperm and male pronuclei
Gregor Jessberger, Csilla Várnai, Roman R Stocsits, Wen Tang, Georg Stary, Jan-Michael Peters.
Genome Res. 2023 Dec 21;33(12):2094-107. doi: 10.1101/gr.277865.123. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38129077/

2023

Diverse macrophage populations contribute to distinct manifestations of human cutaneous graft-versus-host disease
Johanna Strobl, Laura M Gail, Laura Krecu, Shaista Madad, Lisa Kleissl, Luisa Unterluggauer, Anna Redl, Kveta Brazdilova, Simona Saluzzo, Philipp Wohlfarth, Hanna A Knaus, Margit Mitterbauer, Werner Rabitsch, Muzlifah Haniffa, Georg Stary.
Br J Dermatol. 2024 Feb 16;190(3):402-414. doi: 10.1093/bjd/ljad402.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38010706/

2023

Complex interactions of cellular players in chronic Graft-versus-Host Disease
Laura Marie Gail, Kimberly Julia Schell, Piotr Łacina, Johanna Strobl, Steven J Bolton, Emilie Steinbakk Ulriksen, Katarzyna Bogunia-Kubik, Hildegard Greinix, Rachel Emily Crossland, Marit Inngjerdingen, Georg Stary.
Front Immunol. 2023 Jun 26;14:1199422. doi: 10.3389/fimmu.2023.1199422. eCollection 2023.
Abstract: https://pubmed.ncbi.nlm.nih.gov/37435079/

2023

Mast cell-derived BH4 is a critical mediator of postoperative pain
Philipp Starkl, Gustav Jonsson, Tyler Artner, Bruna Lenfers Turnes, Nadine Serhan, Tiago Oliveira, Laura-Marie Gail, Karel Stejskal, Keith M Channon, Thomas Köcher, Georg Stary, Victoria Klang, Nicolas Gaudenzio, Sylvia Knapp, Clifford J Woolf, Josef M Penninger, Shane J F Cronin.
bioRxiv [Preprint]. 2023 Jan 24:2023.01.24.525378. doi: 10.1101/2023.01.24.525378.
Abstract: https://pubmed.ncbi.nlm.nih.gov/37293068/

2023

PRPF19 modulates morphology and growth behavior in a cell culture model of human skin
Lisa Kleissl, Regina Weinmüllner, Ingo Lämmermann, Ruth Dingelmaier-Hovorka, Mohammad Jafarmadar, Abdoelwaheb El Ghalbzouri, Georg Stary, Johannes Grillari, Hanna Dellago.
Front Aging. 2023 May 5;4:1154005. doi: 10.3389/fragi.2023.1154005. eCollection 2023.
Abstract: https://pubmed.ncbi.nlm.nih.gov/37214773/

2023

Functional heterogeneity of human skin-resident memory T cells in health and disease
Johanna Strobl, Muzlifah Haniffa.
Immunol Rev. 2023 Jul;316(1):104-119. doi: 10.1111/imr.13213. Epub 2023 May 5.
Abstract: https://pubmed.ncbi.nlm.nih.gov/37144705/

2023

Good or bad cops: immune cells in aGVHD
Georg Stary.
Blood. 2023 Mar 16;141(11):1238-1240. doi: 10.1182/blood.2022018226.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36929436/

2023

Extracorporeal photopheresis as an immunomodulatory treatment modality for chronic GvHD and the importance of emerging biomarkers
Ines Bojanic, Nina Worel, Carolina P Pacini, Georg Stary, Agnieszka Piekarska, Aisling M Flinn, Kimberly J Schell, Andrew R Gennery, Robert Knobler, João F Lacerda, Hildegard T Greinix, Drazen Pulanic, Rachel E Crossland.
Front Immunol. 2023 Feb 17;14:1086006. doi: 10.3389/fimmu.2023.1086006. eCollection 2023.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36875063/

2023

Polymerase-δ-deficiency as a novel cause of inborn cancer predisposition associated with human papillomavirus infection
Johanna Strobl, Bettina Huber, Raul Jimenez Heredia, Reinhard Kirnbauer, Kaan Boztug, Georg Stary.
Br J Dermatol. 2023 Apr 20;188(5):684-685. doi: 10.1093/bjd/ljad021.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36787285/

2023

Correction: Disturbances in microbial skin recolonization and cutaneous immune response following allogeneic stem cell transfer
Nadine Bayer, Bela Hausmann, Ram Vinay Pandey, Florian Deckert, Laura-Marie Gail, Johanna Strobl, Petra Pjevac, Christoph Krall, Luisa Unterluggauer, Anna Redl, Victoria Bachmayr, Lisa Kleissl, Marion Nehr, Rasmus Kirkegaard, Athanasios Makristathis, Martin L Watzenboeck, Robert Nica, Clement Staud, Lukas Hammerl, Philipp Wohlfarth, Rupert C Ecker, Sylvia Knapp, Werner Rabitsch, David Berry, Georg Stary.
Leukemia. 2023 Mar;37(3):724. doi: 10.1038/s41375-023-01839-7.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36788337/

2023

Single-cell and spatial transcriptomics reveal aberrant lymphoid developmental programs driving granuloma formation
Thomas Krausgruber, Anna Redl, Daniele Barreca, Konstantin Doberer, Daria Romanovskaia, Lina Dobnikar, Maria Guarini, Luisa Unterluggauer, Lisa Kleissl, Denise Atzmüller, Carolina Mayerhofer, Aglaja Kopf, Simona Saluzzo, Clarice X Lim, Praveen Rexie, Thomas Weichhart, Christoph Bock, Georg Stary.
Immunity. 2023 Feb 14;56(2):289-306.e7. doi: 10.1016/j.immuni.2023.01.014. Epub 2023 Feb 6.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36750099/

2023

Epigenetic regulation of T cell lineages in skin and blood following hematopoietic stem cell transplantation
Ram Vinay Pandey, Johanna Strobl, Anna Redl, Luisa Unterluggauer, Laura Gail, Lisa Kleissl, Sophie Müller, Denise Atzmüller, Victoria Fife-Gernedl, Thomas Krausgruber, Hanna Knaus, Margit Mitterbauer, Philipp Wohlfarth, Werner Rabitsch, Christoph Bock, Georg Stary.
Clin Immunol. 2023 Mar;248:109245. doi: 10.1016/j.clim.2023.109245. Epub 2023 Jan 23.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36702179/

2022

Cell-based therapy in prophylaxis and treatment of chronic graft-versus-host disease
Matteo Doglio, Rachel E Crossland, Ana C Alho, Olaf Penack, Anne M Dickinson, Georg Stary, João F Lacerda, Günther Eissner, Marit Inngjerdingen.
Front Immunol. 2022 Nov 17;13:1045168. doi: 10.3389/fimmu.2022.1045168. eCollection 2022.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36466922/

2022

(Not) Home alone: Antigen presenting cell - T Cell communication in barrier tissues
Teresa Neuwirth, Katja Knapp, Georg Stary.
Front Immunol. 2022 Sep 29;13:984356. doi: 10.3389/fimmu.2022.984356. eCollection 2022.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36248804/

2022

Disturbances in microbial skin recolonization and cutaneous immune response following allogeneic stem cell transfer
Nadine Bayer, Bela Hausmann, Ram Vinay Pandey, Florian Deckert, Laura-Marie Gail, Johanna Strobl, Petra Pjevac, Christoph Krall, Luisa Unterluggauer, Anna Redl, Victoria Bachmayr, Lisa Kleissl, Marion Nehr, Rasmus Kirkegaard, Athanasios Makristathis, Martin L Watzenboeck, Robert Nica, Clement Staud, Lukas Hammerl, Philipp Wohlfarth, Rupert C Ecker, Sylvia Knapp, Werner Rabitsch, David Berry, Georg Stary.
Leukemia. 2022 Nov;36(11):2705-2714. doi: 10.1038/s41375-022-01712-z. Epub 2022 Oct 12.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36224329/

2022

Tick feeding modulates the human skin immune landscape to facilitate tick-borne pathogen transmission
Johanna Strobl, Verena Mündler, Sophie Müller, Anna Gindl, Sara Berent, Anna-Margarita Schötta, Lisa Kleissl, Clement Staud, Anna Redl, Luisa Unterluggauer, Ana E Aguilar González, Sophie T Weninger, Denise Atzmüller, Romana Klasinc, Gerold Stanek, Mateusz Markowicz, Hannes Stockinger, Georg Stary.
J Clin Invest. 2022 Nov 1;132(21):e161188. doi: 10.1172/JCI161188.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36166299/

2022

Distinct Chemokine Receptor Expression Profiles in De Novo DLBCL, Transformed Follicular Lymphoma, Richter's Trans-Formed DLBCL and Germinal Center B-Cells
Barbara Uhl, Katharina T Prochazka, Katrin Pansy, Kerstin Wenzl, Johanna Strobl, Claudia Baumgartner, Marta M Szmyra, James E Waha, Axel Wolf, Peter V Tomazic, Elisabeth Steinbauer, Maria Steinwender, Sabine Friedl, Marc Weniger, Ralf Küppers, Martin Pichler, Hildegard T Greinix, Georg Stary, Alan G Ramsay, Benedetta Apollonio, Julia Feichtinger, Christine Beham-Schmid, Peter Neumeister, Alexander J Deutsch.
Int J Mol Sci. 2022 Jul 17;23(14):7874. doi: 10.3390/ijms23147874.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35887224/

2022

Processing human skin samples for single-cell assays
Simona Saluzzo, Laura Marie Gail, Teresa Neuwirth, Ram Vinay Pandey, Matthias Farlik, Georg Stary.
STAR Protoc. 2022 Jun 17;3(3):101470. doi: 10.1016/j.xpro.2022.101470. eCollection 2022 Sep 16.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35769924/

2022

Accumulation of Cytotoxic Skin Resident Memory T Cells and Increased Expression of IL-15 in Lesional Skin of Polymorphic Light Eruption
VijayKumar Patra, Johanna Strobl, Denise Atzmüller, Bärbel Reininger, Lisa Kleissl, Alexandra Gruber-Wackernagel, Jean-Francois Nicolas, Georg Stary, Marc Vocanson, Peter Wolf.
Front Med (Lausanne). 2022 Jun 10;9:908047. doi: 10.3389/fmed.2022.908047. eCollection 2022.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35755042/

Year

Paper

2021

Saluzzo S, Pandey RV, Gail LM, Dingelmaier-Hovorka R, Kleissl L, Shaw L, Reininger B, Atzmüller D, Strobl J, Touzeau-Römer V, Beer A, Staud C, Rieger A, Farlik M, Weninger W, Stingl G, Stary G. Delayed antiretroviral therapy in HIV-infected individuals leads to irreversible depletion of skin- and mucosa-resident memory T cells. Immunity. 2021 Dec 14;54(12):2842-2858.e5. doi: 10.1016/j.immuni.2021.10.021. Epub 2021 Nov 22.
Abstract: https://pubmed.ncbi.nlm.nih.gov/34813775/

2021

Strobl J, Gail LM, Kleissl L, Pandey RV, Smejkal V, Huber J, Puxkandl V, Unterluggauer L, Dingelmaier-Hovorka R, Atzmüller D, Krausgruber T, Bock C, Wohlfarth P, Rabitsch W, Stary G. Human resident memory T cells exit the skin and mediate systemic Th2-driven inflammation. J Exp Med. 2021 Nov 1;218(11):e20210417. doi: 10.1084/jem.20210417. Epub 2021 Oct 13.
Abstract: https://pubmed.ncbi.nlm.nih.gov/34643646/

2021

Saluzzo S, Pandey RV, Gail LM, Dingelmaier-Hovorka R, Kleissl L, Shaw L, Reininger B, Atzmüller D, Strobl J, Touzeau-Römer V, Beer A, Staud C, Rieger A, Farlik M, Weninger W, Stingl G, Stary G. Delayed antiretroviral therapy in HIV-infected individuals leads to irreversible depletion of skin- and mucosa-resident memory T cells. Immunity. 2021 Nov 16;S1074-7613(21)00459-3. doi: 10.1016/j.immuni.2021.10.021. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/34813775/

2021

Strobl J, Pandey RV, Krausgruber T, Bayer N, Kleissl L, Reininger B, Vieyra-Garcia P, Wolf P, Jentus MM, Mitterbauer M, Wohlfarth P, Rabitsch W, Stingl G, Bock C, Stary G. Long-term skin-resident memory T cells proliferate in situ and are involved in human graft-versus-host disease. Sci Transl Med. 2020 Nov 18;12(570):eabb7028. doi: 10.1126/scitranslmed.abb7028.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33208504/ _blank

2021

Unterluggauer L, Pospischil I, Krall C, Saluzzo S, Kimeswenger S, Karolyi M, Wenisch C, Lamprecht B, Guenova E, Winkler S, Viczenczova C, Bergthaler A, Weninger W, Hoetzenecker W, Stary G. Cutaneous manifestations of SARS-CoV-2: A 2-center, prospective, case-controlled study. J Am Acad Dermatol. 2021 Jul;85(1):202-204. doi: 10.1016/j.jaad.2021.03.064. Epub 2021 Mar 23.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33771589/ _blank

2021

Kopf A, Kiermaier E. Dynamic Microtubule Arrays in Leukocytes and Their Role in Cell Migration and Immune Synapse Formation. Front Cell Dev Biol. 2021 Feb 9;9:635511. doi: 10.3389/fcell.2021.635511. eCollection 2021.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33634136/

2021

Unterluggauer L, Pospischil I, Krall C, Saluzzo S, Kimeswenger S, Karolyi M, Wenisch C, Lamprecht B, Guenova E, Winkler S, Viczenczova C, Bergthaler A, Weninger W, Hoetzenecker W, Stary G. Cutaneous manifestations of SARS-CoV-2: A 2-center, prospective, case-controlled study. J Am Acad Dermatol. 2021 Mar 23:S0190-9622(21)00619-8. doi: 10.1016/j.jaad.2021.03.064. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33771589/

2020

Strobl J, Pandey RV, Krausgruber T, Kleissl L, Reininger B, Herac M, Bayer N, Krall C, Wohlfarth P, Mitterbauer M, Kalhs P, Rabitsch W, Bock C, Hopfinger G, Stary G. Anti-Apoptotic Molecule BCL2 Is a Therapeutic Target in Steroid-Refractory Graft-Versus-Host Disease. J Invest Dermatol. 2020 Nov;140(11):2188-2198. doi: 10.1016/j.jid.2020.02.029. Epub 2020 Apr 2.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32247860/

2020

Stary V, Pandey RV, Strobl J, Kleissl L, Starlinger P, Pereyra D, Weninger W, Fischer GF, Bock C, Farlik M, Stary G. A discrete subset of epigenetically primed human NK cells mediates antigen-specific immune responses. Sci Immunol. 2020 Oct 16;5(52):eaba6232. doi: 10.1126/sciimmunol.aba6232.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33067380/

2020

Strobl J, Pandey RV, Krausgruber T, Kleissl L, Reininger B, Herac M, Bayer N, Krall C, Wohlfarth P, Mitterbauer M, Kalhs P, Rabitsch W, Bock C, Hopfinger G, Stary G. Anti-Apoptotic Molecule BCL2 Is a Therapeutic Target in Steroid- Refractory Graft-Versus-Host Disease. J Invest Dermatol. 2020 Apr 2:S0022-202X(20)31252-5. doi: 10.1016/j.jid.2020.02.029. Epub ahead of print.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32247860

2019

Patra V, Strobl J, Gruber-Wackernagel A, Vieyra-Garcia P, Stary G, Wolf P. CD11b(+) cells markedly express the itch cytokine interleukin-31 in polymorphic light eruption. Br J Dermatol. 2019 May 3. doi: 10.1111/bjd.18092. [Epub ahead ofprint]
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31049931