Publications
2025
Eosinophil innate immune memory after bacterial skin infection promotes allergic lung inflammation
Mariem Radhouani,
Asma Farhat,
Anna Hakobyan,
Sophie Zahalka,
Lisabeth Pimenov,
Alina Fokina,
Anastasiya Hladik,
Karin Lakovits,
Jessica Brösamlen,
Vojtech Dvorak,
Natalia Nunes,
Andreas Zech,
Marco Idzko,
Thomas Krausgruber,
Jörg Köhl,
Ozge Uluckan,
Jiri Kovarik,
Kai Hoehlig,
Axel Vater,
Margret Eckhard,
Andy Sombke,
Nikolaus Fortelny,
Jörg Menche,
Sylvia Knapp,
Philipp Starkl.
Sci Immunol. 2025 Apr 4;10(106):eadp6231. doi: 10.1126/sciimmunol.adp6231. Epub 2025 Apr 4.
2025
The polyamine-regulating enzyme SSAT1 impairs tissue regulatory T cell function in chronic cutaneous inflammation
Teresa Neuwirth,
Daniel Malzl,
Katja Knapp,
Panagiota Tsokkou,
Lisa Kleissl,
Anna Gabriel,
Baerbel Reininger,
Christian Freystätter,
Nara Marella,
Ana P Kutschat,
Elisabeth Ponweiser,
Arvand Haschemi,
Davide Seruggia,
Jörg Menche,
Erwin F Wagner,
Georg Stary.
Immunity. 2025 Mar 11;58(3):632-647.e12. doi: 10.1016/j.immuni.2025.02.011. Epub 2025 Feb 28.
2024
Deep proteomics and network pharmacology reveal sex- and age-shared neuropathic pain signatures in mouse dorsal root ganglia
Sabrina Grundtner,
Julia R Sondermann,
Feng Xian,
Daniel Malzl,
Daniel Segelcke,
Esther M Pogatzki-Zahn,
Jörg Menche,
David Gómez-Varela,
Manuela Schmidt.
Pharmacol Res. 2025 Jan;211:107552. doi: 10.1016/j.phrs.2024.107552. Epub 2024 Dec 16.
2024
Pan-cancer analysis of the interplay between mutational signatures and cellular signaling
Anna Hakobyan,
Mathilde Meyenberg,
Nelli Vardazaryan,
Joel Hancock,
Loan Vulliard,
Joanna I Loizou,
Jörg Menche.
iScience. 2024 May 2;27(6):109873. doi: 10.1016/j.isci.2024.109873. eCollection 2024 Jun 21.
2024
Network cartographs for interpretable visualizations
Christiane V R Hütter,
Celine Sin,
Felix Müller,
Jörg Menche.
Nat Comput Sci. 2022 Feb;2(2):84-89. doi: 10.1038/s43588-022-00199-z. Epub 2022 Feb 24.
2023
RIF1 regulates early replication timing in murine B cells
Daniel Malzl,
Mihaela Peycheva,
Ali Rahjouei,
Stefano Gnan,
Kyle N Klein,
Mariia Nazarova,
Ursula E Schoeberl,
David M Gilbert,
Sara C B Buonomo,
Michela Di Virgilio,
Tobias Neumann,
Rushad Pavri.
Nat Commun. 2023 Dec 11;14(1):8049. doi: 10.1038/s41467-023-43778-y.
2023
Proteomics and disease network associations evaluation of environmentally relevant Bisphenol A concentrations in a human 3D neural stem cell model
Alex Horánszky,
Bachuki Shashikadze,
Radwa Elkhateib,
Salvo Danilo Lombardo,
Federica Lamberto,
Melinda Zana,
Jörg Menche,
Thomas Fröhlich,
András Dinnyés.
Front Cell Dev Biol. 2023 Aug 16;11:1236243. doi: 10.3389/fcell.2023.1236243. eCollection 2023.
2023
Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients
Kumar Sharma,
Guanshi Zhang,
Jens Hansen,
Petter Bjornstad,
Hak Joo Lee,
Rajasree Menon,
Leila Hejazi,
Jian-Jun Liu,
Anthony Franzone,
Helen C Looker,
Byeong Yeob Choi,
Roman Fernandez,
Manjeri A Venkatachalam,
Luxcia Kugathasan,
Vikas S Sridhar,
Loki Natarajan,
Jing Zhang,
Varun S Sharma,
Brian Kwan,
Sushrut S Waikar,
Jonathan Himmelfarb,
Katherine R Tuttle,
Bryan Kestenbaum,
Tobias Fuhrer,
Harold I Feldman,
Ian H de Boer,
Fabio C Tucci,
John Sedor,
Hiddo Lambers Heerspink,
Jennifer Schaub,
Edgar A Otto,
Jeffrey B Hodgin,
Matthias Kretzler,
Christopher R Anderton,
Theodore Alexandrov,
David Cherney,
Su Chi Lim,
Robert G Nelson,
Jonathan Gelfond,
Ravi Iyengar,
Kidney Precision Medicine Project.
J Clin Invest. 2023 Oct 16;133(20):e170341. doi: 10.1172/JCI170341.
2023
Low-dose Bisphenol A exposure alters the functionality and cellular environment in a human cardiomyocyte model
Federica Lamberto,
Bachuki Shashikadze,
Radwa Elkhateib,
Salvo Danilo Lombardo,
Alex Horánszky,
Andrea Balogh,
Kornél Kistamás,
Melinda Zana,
Jörg Menche,
Thomas Fröhlich,
András Dinnyés.
Environ Pollut. 2023 Oct 15;335:122359. doi: 10.1016/j.envpol.2023.122359. Epub 2023 Aug 9.
2023
Maternal hyperglycemia induces alterations in hepatic amino acid, glucose and lipid metabolism of neonatal offspring: Multi-omics insights from a diabetic pig model
Bachuki Shashikadze,
Libera Valla,
Salvo Danilo Lombardo,
Cornelia Prehn,
Mark Haid,
Fabien Riols,
Jan Bernd Stöckl,
Radwa Elkhateib,
Simone Renner,
Birgit Rathkolb,
Jörg Menche,
Martin Hrabĕ de Angelis,
Eckhard Wolf,
Elisabeth Kemter,
Thomas Fröhlich.
Mol Metab. 2023 Sep;75:101768. doi: 10.1016/j.molmet.2023.101768. Epub 2023 Jul 4.
