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Georg Stary

Georg Stary

Translational Immunology of the Skin and Mucous Membranes

Research Focus

The research projects of Georg Stary focus on various aspects of host-pathogen interactions and the role of tissue-resident leukocytes in both physiological and pathological immune responses. Georg’s research interest lies in the biology, longevity, turnover, and function of tissue-resident leukocytes in peripheral tissues, with the skin serving as an optimal and accessible organ for conducting meaningful human immunology experiments. Georg Stary is a member of the Immuno-Board for Rare and Undiagnosed Diseases, organized by LBI-RUD and CeRUD Director Kaan Boztug, and the Stary laboratory applies advanced omics technologies in collaboration with research groups at CeMM and LBI-RUD.

Biosketch

Georg Stary is a fully trained dermatovenereologist with direct contact to patients and ample experience in research in organ-specific immunological processes. After a four-year fellowship in the von Andrian Laboratory at Harvard Medical School, he became senior physician and principal investigator to the Department of Dermatology of the Medical University of Vienna in 2014. He was appointed assistant professor in 2015 and associate professor in 2016. Since November 2018, he has been an adjunct principal investigator at LBI-RUD and CeMM and has since been named co-director of LBI-RUD. His research projects focus on different aspects of host-pathogen interactions and the contribution of tissue-resident leukocytes to physiological and pathological immune responses. His research projects are in the areas of biology, immune cell longevity, and turnover and function of tissue-resident leukocytes in peripheral tissue. The skin often serves as model tissue, as it is accessible for translational experimental setups. He is a member of the Immuno-Board for Rare and Undiagnosed Diseases organized by LBI-RUD and CeRUD, a board member of the Society of Dermatological Research for Germany, Austria, and Switzerland (ADF), a board member of the Austrian Society of Dermatology and Venerology (ÖGDV), chair of the Austrian Society of Sexually Transmitted Diseases and Dermatological Microbiology (ÖGSTD), treasurer of the Austrian Society for Allergy and Immunology (ÖGAI), and member of various other national and international societies. In 2022, Georg Stary was awarded the Ferdinand von Hebra Prize by the ÖGDV. He received the prize for his comprehensive research on the role of immune cells in host-pathogen interactions in physiological and pathological conditions of the skin and mucous membranes that has led to significant progress in the field of dermatological research.

Top 5 Publications

  1. Neuwirth T, Malzl D, Knapp K, et al. The polyamine-regulating enzyme SSAT1 impairs tissue regulatory T cell function in chronic cutaneous inflammation. Immunity. 2025;58(3):632-647.e12. doi:10.1016/j.immuni.2025.02.011. (published paper)

  2. Krausgruber T, Redl A, Barreca D, et al. Single-cell and spatial transcriptomics reveal aberrant lymphoid developmental programs driving granuloma formation. Immunity. 2023;56(2):289-306.e7. doi:10.1016/j.immuni.2023.01.014. (published paper)

  3. Saluzzo S, Pandey RV, Gail LM, et al. Delayed antiretroviral therapy in HIV-infected individuals leads to irreversible depletion of skin- and mucosa-resident memory T cells. Immunity. 2021;54(12):2842-2858.e5. doi:10.1016/j.immuni.2021.10.021. (published paper)

  4. Strobl J, Pandey RV, Krausgruber T, et al. Long-term skin resident memory T cells proliferate in situ and are involved in human graft-versus-host disease. Sci Transl Med. 2020;12(570):eabb7028. doi:10.1126/scitranslmed.abb7028. (published paper)

  5. Stary G, Olive A, Radovic-Moreno AF, et al. A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells. Science. 2015;348(6241):aaa8205. doi:10.1126/science.aaa8205. (published paper)

 

Please visit Georg Stary's Google Scholar profile for a complete list of publications.