Publications
2025
Mitotic lethality prevents inflammation
Christian Zierhut,
Andreas Villunger.
Nat Cell Biol. 2025 Jan;27(1):7-8. doi: 10.1038/s41556-024-01529-1.
2024
Global analysis of endogenous protein disorder in cells
Shouxiang Zhang,
Tze Cin Owyong,
Oana Sanislav,
Lukas Englmaier,
Xiaojing Sui,
Geqing Wang,
David W Greening,
Nicholas A Williamson,
Andreas Villunger,
Jonathan M White,
Begoña Heras,
Wallace W H Wong,
Paul R Fisher,
Yuning Hong.
Nat Methods. 2025 Jan;22(1):124-134. doi: 10.1038/s41592-024-02507-z. Epub 2024 Nov 25.
2024
Caspase-2 kills cells with extra centrosomes
Dario Rizzotto,
Vincenza Vigorito,
Patricia Rieder,
Filip Gallob,
Gian Mario Moretta,
Claudia Soratroi,
Joel S Riley,
Florian Bellutti,
Stefano Li Veli,
Alessia Mattivi,
Michael Lohmüller,
Sebastian Herzog,
Beat C Bornhauser,
Etienne D Jacotot,
Andreas Villunger,
Luca L Fava.
Sci Adv. 2024 Nov;10(44):eado6607. doi: 10.1126/sciadv.ado6607. Epub 2024 Oct 30.
2024
Centrioles are frequently amplified in early B cell development but dispensable for humoral immunity
Marina A Schapfl,
Gina M LoMastro,
Vincent Z Braun,
Maretoshi Hirai,
Michelle S Levine,
Eva Kiermaier,
Verena Labi,
Andrew J Holland,
Andreas Villunger.
Nat Commun. 2024 Oct 15;15(1):8890. doi: 10.1038/s41467-024-53222-4.
2024
Cyclin C promotes development and progression of B-cell acute lymphoblastic leukemia by counteracting p53-mediated stress responses
Jana Trifinopoulos,
Julia List,
Thorsten Klampfl,
Klara Klein,
Michaela Prchal-Murphy,
Agnieszka Witalisz-Siepracka,
Florian Bellutti,
Luca L Fava,
Gerwin Heller,
Sarah Stummer,
Patricia Testori,
Monique L Den Boer,
Judith M Boer,
Sonja Marinovic,
Gregor Hoermann,
Wencke Walter,
Andreas Villunger,
Piotr Sicinski,
Veronika Sexl,
Dagmar Gotthardt.
Haematologica. 2025 Apr 1;110(4):877-892. doi: 10.3324/haematol.2024.285701. Epub 2024 Oct 10.
2024
Concerted transcriptional regulation of the morphogenesis of hypothalamic neurons by ONECUT3
Maja Zupančič,
Erik Keimpema,
Evgenii O Tretiakov,
Stephanie J Eder,
Itamar Lev,
Lukas Englmaier,
Pradeep Bhandari,
Simone A Fietz,
Wolfgang Härtig,
Estelle Renaux,
Andreas Villunger,
Tomas Hökfelt,
Manuel Zimmer,
Frédéric Clotman,
Tibor Harkany.
Nat Commun. 2024 Oct 5;15(1):8631. doi: 10.1038/s41467-024-52762-z.
2024
Amplified centrosomes-more than just a threat
Eva Kiermaier,
Isabel Stötzel,
Marina A Schapfl,
Andreas Villunger.
EMBO Rep. 2024 Oct;25(10):4153-4167. doi: 10.1038/s44319-024-00260-0. Epub 2024 Sep 16.
2024
Chronic spindle assembly checkpoint activation causes myelosuppression and gastrointestinal atrophy
Gerlinde Karbon,
Fabian Schuler,
Vincent Z Braun,
Felix Eichin,
Manuel Haschka,
Mathias Drach,
Rocio Sotillo,
Stephan Geley,
Diana Cj Spierings,
Andrea E Tijhuis,
Floris Foijer,
Andreas Villunger.
EMBO Rep. 2024 Jun;25(6):2743-2772. doi: 10.1038/s44319-024-00160-3. Epub 2024 May 28.
2024
Extra centrosomes delay DNA damage-driven tumorigenesis
Vincent Z Braun,
Gerlinde Karbon,
Fabian Schuler,
Marina A Schapfl,
Johannes G Weiss,
Paul Y Petermann,
Diana C J Spierings,
Andrea E Tijhuis,
Floris Foijer,
Verena Labi,
Andreas Villunger.
Sci Adv. 2024 Mar 29;10(13):eadk0564. doi: 10.1126/sciadv.adk0564. Epub 2024 Mar 29.
2023
Non-canonical BIM-regulated energy metabolism determines drug-induced liver necrosis
Rebekka Lambrecht,
Franziska Rudolf,
Anna-Katharina Ückert,
Valentina C Sladky,
Truong San Phan,
Jasmin Jansen,
Samara Naim,
Thomas Kaufmann,
Adrian Keogh,
Susanne Kirschnek,
Aswin Mangerich,
Florian Stengel,
Marcel Leist,
Andreas Villunger,
Thomas Brunner.
Cell Death Differ. 2024 Jan;31(1):119-131. doi: 10.1038/s41418-023-01245-7. Epub 2023 Nov 24.
