- National Funding
- CD Laboratory for Chemical Epigenetics and Antiinfectives
- FFG Bridge "ImmunoDegraders"
- FWF DK W 1212-B21 "IAI"
- FWF SFB F 4711-B20 "Myeloproliferative Neoplasms"
- FWF SFB F 6102-B21 "Chromatin Landscapes"
- FWF SFB F 5402-B21 "Microparticles as modulators of inflammation and thrombosis"
- FWF SFB F 4701-B20 "Myeloproliferative Neoplasms"
- FWF SFB F 7002-B21 "HDACs as regulators of T cell-mediated immunity in health and disease"
- FWF SFB F 7909-B "Chemical probing and functional characterization of the E3 substrate receptor DCAF15"
- FWF Stand-Alone P 29763-B27
- FWF Stand-Alone P 30047-B30
- FWF Stand-Alone P 30271 - B28
- FWF Stand-Alone P 32125-B
- FWF Stand-Alone P 31690-B28
- FWF Stand-Alone P 30041-B26
- FWF Stand-Alone P 31113-B30
- FWF TRANSCAN I 2798-B28 "CEVIR"
- OeAW New Frontier Group 2013
- OeAW NFRI 2015
- WWTF Vienna Research Group Leader
- WWTF LS16-034 "PHARMACOSCOPY"
- WWTF LS16-060 "PrecisePID"
- WWTF LS17-059 "3C - Cellular Color Chart"
- WWTF LS18 - 058 "Systems medicine analysis of sarcoidosis by targeting mTOR in a co-clinical trial in patients and mice"
- WWTF LS18 - 049 "Characterizing and targeting the Ewing sarcoma microenvironment to overcome resistance to therapy"
- WWTF LS18 - 111 "Ultra-high-risk pediatric cancer - combinatorial drivers and therapeutic targets for precision medicine"
- WWTF NXT19-008 "DataDiVR"
- International Funding
Chemical probing and functional characterization of the E3 substrate receptor DCAF15
The targeted degradation of proteins is of utmost importance for the well-being of our cells and thus for the entire organism. Damaged proteins must be recognized and removed to prevent collateral damage. In addition, proteins must be removed in a targeted manner in order to allow the activation, but also the deactivation of cellular signal transduction pathways. Defects in the targeted degradation of proteins can result in diseases such as cancer and neurodegeneration.
The Special Research Program, SFB F79, is funded by the Austrian Science Fund (FWF) with contributions by the German Research Foundation (DFG).
The collaborative research program includes scientists from Max Perutz Labs, University of Vienna, Medical University of Vienna, CeMM, GMI, IMBA and IMP from Vienna as well as IMB in Mainz, who have joined forces to discover mechanism of targeted protein degradation, and how this process can be manipulated.