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Year
Paper
2021
Starkl P, Gaudenzio N, Marichal T, Reber LL, Sibilano R, Watzenboeck ML, Fontaine F, Mueller AC, Tsai M, Knapp S, Galli SJ. IgE antibodies increase honeybee venom responsiveness and detoxification efficiency of mast cells. Allergy. 2021 Apr 11. doi: 10.1111/all.14852. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33840121/
2021
Watzenboeck ML, Drobits B, Zahalka S, Gorki AD, Farhat A, Quattrone F, Hladik A, Lakovits K, Richard GM, Lederer T, Strobl B, Versteeg GA, Boon L, Starkl P, Knapp S. Lipocalin 2 modulates dendritic cell activity and shapes immunity to influenza in a microbiome dependent manner. PLoS Pathog. 2021 Apr 27;17(4):e1009487. doi: 10.1371/journal.ppat.1009487. eCollection 2021 Apr.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33905460/
2020
Lang C, Jaksch P, Hoda MA, Lang G, Staudinger T, Tschernko E, Zapletal B, Geleff S, Prosch H, Gawish R, Knapp S, Robak O, Thalhammer F, Indra A, Koestenberger M, Strassl R, Klikovits T, Ali K, Fischer G, Klepetko W, Hoetzenecker K, Schellongowski P. Lung transplantation for COVID-19-associated acute respiratory distress syndrome in a PCR-positive patient. Lancet Respir Med. 2020 Oct;8(10):1057-1060. doi: 10.1016/S2213-2600(20)30361-1. Epub 2020 Aug 25.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32857987/
2020
Esparza-Baquer A, Labiano I, Sharif O, Agirre-Lizaso A, Oakley F, Rodrigues PM, Zhuravleva E, O'Rourke CJ, Hijona E, Jimenez-Agüero R, Riaño I, Landa A, La Casta A, Zaki MYW, Munoz-Garrido P, Azkargorta M, Elortza F, Vogel A, Schabbauer G, Aspichueta P, Andersen JB, Knapp S, Mann DA, Bujanda L, Banales JM, Perugorria MJ. TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms. Gut. 2020 Sep 9:gutjnl-2019-319227. doi: 10.1136/gutjnl-2019-319227. Epub ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32907830/
2020
Starkl P, Watzenboeck ML, Popov LM, Zahalka S, Hladik A, Lakovits K, Radhouani M, Haschemi A, Marichal T, Reber LL, Gaudenzio N, Sibilano R, Stulik L, Fontaine F, Mueller AC, Amieva MR, Galli SJ, Knapp S. IgE Effector Mechanisms, in Concert with Mast Cells, Contribute to Acquired Host Defense against Staphylococcusaureus. Immunity. 2020 Oct 13;53(4):793-804.e9. doi: 10.1016/j.immuni.2020.08.002. Epub 2020 Sep 9. Erratum in: Immunity. 2020 Dec 15;53(6):1333.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32910906/
2020
Ubags NDJ, Alejandre Alcazar MA, Kallapur SG, Knapp S, Lanone S, Lloyd CM, Morty RE, Pattaroni C, Reynaert NL, Rottier RJ, Smits HH, de Steenhuijsen Piters WAA, Strickland DH, Collins JJP. Early origins of lung disease: towards an interdisciplinary approach. Eur Respir Rev. 2020 Oct 1;29(157):200191. doi: 10.1183/16000617.0191-2020.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33004528/
2020
Schwarz S, Rahimi N, Kifjak D, Muckenhuber M, Watzenböck M, Benazzo A, Jaksch P, Knapp S, Klepetko W, Hoetzenecker K; Vienna Lung Transplant Group. Comparison of donor scores in bilateral lung transplantation-A large single-center analysis. Am J Transplant. 2020 Nov 19. doi: 10.1111/ajt.16402. Epub ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33210825/
2020
Starkl P, Watzenboeck M L, Popov L M, Zahalka S, Hladik A, Lakovits K, Radhouani M, Haschemi A, Marichal T, Reber L L, Gaudenzio N, Sibilano R, Stulik L, Fontaine F, Mueller A C, Amieva M R, Galli S J, Knapp S. IgE Effector Mechanisms, in Concert with Mast Cells, Contribute to Acquired Host Defense against Staphylococcusaureus. Immunity. 2020 Oct 13;53(4):793-804.e9. doi: 10.1016/j.immuni.2020.08.002. Epub 2020 Sep 9.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32910906/
2020
Hainberger D, Stolz V, Zhu C, Schuster M, Müller L, Hamminger P, Rica R, Waltenberger D, Alteneder M, Krausgruber T, Hladik A, Knapp S, Bock C, Trauner M, Farrar MA, Ellmeier W. NCOR1 Orchestrates Transcriptional Landscapes and Effector Functions of CD4+ T Cells. Front Immunol. 2020 Apr 3;11:579. doi: 10.3389/fimmu.2020.00579.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32318068
2019
Serhan N, Basso L, Sibilano R, Petitfils C, Meixiong J, Bonnart C, Reber LL, Marichal T, Starkl P, Cenac N, Dong X, Tsai M, Galli SJ, Gaudenzio N. House dust mites activate nociceptor-mast cell clusters to drive type 2 skin inflammation. Nat Immunol. 2019 Nov;20(11):1435-1443. doi: 10.1038/s41590-019-0493-z.
Abstract: https://pubmed.ncbi.nlm.nih.gov/31591569/
2019
Kral-Pointner JB, Schrottmaier WC, Salzmann M, Mussbacher M, Schmidt GJ, Moser B, Heber S, Birnecker B, Paar H, Zellner M, Knapp S, Assinger A, Schabbauer G. Platelet PI3K Modulates Innate Leukocyte Extravasation during Acid-Induced Acute Lung Inflammation. Thromb Haemost. 2019;19(10):1642–1654. doi:10.1055/s-0039-1693693
Abstract: https://pubmed.ncbi.nlm.nih.gov/31370072/
2019
Klufa J, Bauer T, Hanson B, Herbold C, Starkl P, Lichtenberger B, Srutkova D, Schulz D, Vujic I, Mohr T, Rappersberger K, Bodenmiller B, Kozakova H, Knapp S, Loy A, Sibilia M. Klufa J, Bauer T, Hanson B, et al. Hair eruption initiates and commensal skin microbiota aggravate adverse events of anti-EGFR therapy. Sci Transl Med. 2019;11(522):eaax2693. doi:10.1126/scitranslmed.aax2693
Abstract: https://pubmed.ncbi.nlm.nih.gov/31826981/
2019
Göschl L, Preglej T, Boucheron N, Saferding V, Müller L, Platzer A, Hirahara K, Shih H-Y, Backlund J, Matthias P, Niederreiter B, Hladik A, Kugler M, Gualdoni GA, Scheinecker C, Knapp S, Seiser C, Holmdahl R, Tillmann K, Plasenzotti R, Podesser B, Aletaha D, Smolen JS, Karonitsch T, Steiner G, Ellmeier W, Bonelli M. Histone deacetylase 1 (HDAC1): A key player of T cell-mediated arthritis. J Autoimmun. 2019;102379. doi:10.1016/j.jaut.2019.102379
Abstract: https://pubmed.ncbi.nlm.nih.gov/31883829/
2019
Andersen L, Gülich AF, Alteneder M, Preglej T, Orola MJ, Dhele N, Stolz V, Schebesta A, Hamminger P, Hladik A, Floess S, Krausgruber T, Faux T, Andrabi SBA, Huehn J, Knapp S, Sparwasser T, Bock C, Laiho A, Elo LL, Rasool O, Lahesmaa R, Sakaguchi S, Ellmeier W. The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells. Cell Rep. 2019;29(13):4447–4459.e6. doi:10.1016/j.celrep.2019.11.089
Abstract: https://pubmed.ncbi.nlm.nih.gov/31875552/
2018
Faust K, Bauchinger F, Laroche B, de Buyl S, Lahti L, Washburne AD, Gonze D, Widder S. Signatures of ecological processes in microbial community time series. Microbiome. 2018 Jun 28;6(1):120. doi: 10.1186/s40168-018-0496-2.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29954432
2018
Cohen M, Giladi A, Gorki AD, Solodkin DG, Zada M, Hladik A, Miklosi A, Salame TM, Halpern KB, David E, Itzkovitz S, Harkany T, Knapp S, Amit I. Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting. Cell. 2018 Nov 1;175(4):1031-1044.e18. doi: 10.1016/j.cell.2018.09.009. Epub 2018 Oct 11.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30318149
2018
Balbino B, Conde E, Marichal T, Starkl P, Reber LL. Approaches to target IgE antibodies in allergic diseases. Pharmacol Ther. 2018 Nov;191:50-64. doi: 10.1016/j.pharmthera.2018.05.015. Epub 2018 Jun 27. Review.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29909239
2018
Martins R, Knapp S. Heme and hemolysis in innate immunity: adding insult to injury. Curr Opin Immunol. 2018 Feb;50:14-20. doi: 10.1016/j.coi.2017.10.005. Epub 2017 Nov 5. Review.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29107115
2018
Matt U, Selchow P, Molin MD, Strommer S, Sharif O, Schilcher K, Andreoni F, Stenzinger A, Zinkernagel AS, Zeitlinger M, Sander P, Nemeth J. Corrigendum to 'Chloroquine enhances the antimycobacterial activity of isoniazid and pyrazinamide by reversing inflammation-induced macrophage efflux' [The International Journal of Antimicrobial Agents 50/1 (2017) 55-62]. Int J Antimicrob Agents. 2018 Jan;51(1):122. doi: 10.1016/j.ijantimicag.2017.10.012. Epub 2017 Nov 14.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29150181
2018
Perugorria MJ, Esparza-Baquer A, Oakley F, Labiano I, Korosec A, Jais A, Mann J, Tiniakos D, Santos-Laso A, Arbelaiz A, Gawish R, Sampedro A, Fontanellas A, Hijona E, Jimenez-Agüero R, Esterbauer H, Stoiber D, Bujanda L, Banales JM, Knapp S, Sharif O, Mann DA. Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage. Gut. 2018 Jan 27. pii: gutjnl-2017-314107. doi: 10.1136/gutjnl-2017-314107. [Epub ahead of print]
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29374630
2017
Busch CJ, Hendrikx T, Weismann D, Jäckel S, Walenbergh SM, Rendeiro AF, Weißer J, Puhm F, Hladik A, Göderle L, Papac-Milicevic N, Haas G, Millischer V, Subramaniam S, Knapp S, Bennett KL, Bock C, Reinhardt C, Shiri-Sverdlov R, Binder CJ. Malondialdehyde epitopes are sterile mediators of hepatic inflammation in hypercholesterolemic mice. Hepatology. 2017 Apr;65(4):1181-1195. doi: 10.1002/hep.28970. Epub 2017 Feb 3.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/27981604
2017
Saluzzo S, Gorki AD, Rana BMJ, Martins R, Scanlon S, Starkl P, Lakovits K, Hladik A, Korosec A, Sharif O, Warszawska JM, Jolin H, Mesteri I, McKenzie ANJ, Knapp S. First-Breath-Induced Type 2 Pathways Shape the Lung Immune Environment. Cell Rep. 2017 Feb 21;18(8):1893-1905. doi: 10.1016/j.celrep.2017.01.071.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28228256
2017
Matt U, Selchow P, Dal Molin M, Strommer S, Sharif O, Schilcher K, Andreoni F, Stenzinger A, Zinkernagel AS, Zeitlinger M, Sander P, Nemeth J. Chloroquine enhances the antimycobacterial activity of isoniazid and pyrazinamide by reversing inflammation-induced macrophage efflux. Int J Antimicrob Agents. 2017 Jul;50(1):55-62. doi: 10.1016/j.ijantimicag.2017.02.022. Epub 2017 May 12.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28506804
2017
Kral-Pointner JB, Schrottmaier WC, Horvath V, Datler H, Hell L, Ay C, Niederreiter B, Jilma B, Schmid JA, Assinger A, Mackman N, Knapp S, Schabbauer G. Myeloid but not epithelial tissue factor exerts protective anti-inflammatory effects in acid aspiration-induced acute lung injury. J Thromb Haemost. 2017 Aug;15(8):1625-1639. doi: 10.1111/jth.13737. Epub 2017 Jun 20.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28509332
2017
Miller A, Nagy C, Knapp B, Laengle J, Ponweiser E, Groeger M, Starkl P, Bergmann M, Wagner O, Haschemi A. Exploring Metabolic Configurations of Single Cells within Complex Tissue Microenvironments. Cell Metab. 2017 Nov 7;26(5):788-800.e6. doi: 10.1016/j.cmet.2017.08.014. Epub 2017 Sep 7.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28889950
2017
Kosack L, Gawish R, Lercher A, Vilagos B, Hladik A, Lakovits K, Bhattacharya A, Schliehe C, Mesteri I, Knapp S, Bergthaler A. The lipid-sensor TREM2 aggravates disease in a model of LCMV-induced hepatitis. Sci Rep. 2017 Sep 12;7(1):11289. doi: 10.1038/s41598-017-10637-y.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28900132
2017
Martins R, Knapp S. Heme and hemolysis in innate immunity: adding insult to injury. Curr Opin Immunol. 2017 Oct 26;50:14-20. doi: 10.1016/j.coi.2017.10.005. [Epub ahead of print] Review.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29107115
2017
Simona Saluzzo, Anna-Dorothea Gorki, Batika M.J. Rana, Rui Martins, Seth Scanlon, Philipp Starkl, Karin Lakovits, Anastasiya Hladik, Ana Korosec, Omar Sharif, Joanna M. Warszawska, Helen Jolin, Ildiko Mesteri, Andrew N.J. McKenzie, Sylvia Knapp. First-Breath-Induced Type 2 Pathways Shape the Lung Immune Environment. Cell Rep. 2017 Feb 21; 18(8): 1893–1905. DOI:http://dx.doi.org/10.1016/j.celrep.2017.01.071.
Abstract: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329122/
2012
Laimer, D., H. Dolznig, K. Kollmann, P.W. Vesely, M. Schlederer, O. Merkel, A.I. Schiefer, M.R. Hassler, S. Heider, L. Amenitsch, C. Thallinger, P.B. Staber, I. Simonitsch-Klupp, M. Artaker, S. Lagger, S.D. Turner, S. Pileri, P.P. Piccaluga, P. Valent, K. Messana, I. Landra, T. Weichhart, S. Knapp, M. Shehata, M. Todaro, V. Sexl, G. Hofler, R. Piva, E. Medico, B.A. Ruggeri, M. Cheng, R. Eferl, G. Egger, J.M. Penninger, U. Jaeger, R. Moriggl, G. Inghirami, and L. Kenner, PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas. Nat Med, 2012. 18(11): p. 1699-704.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/23064464
2013
Knapp, S., Diabetes and infection: is there a link?--A mini-review. Gerontology, 2013. 59(2): p. 99-104.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/23182884
2015
Gawish, R., R. Martins, B. Bohm, T. Wimberger, O. Sharif, K. Lakovits, M. Schmidt, and S. Knapp, Triggering receptor expressed on myeloid cells-2 fine-tunes inflammatory responses in murine Gram-negative sepsis. FASEB J, 2015. 29(4): p. 1247-57.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25477281
2015
Matt, U., O. Sharif, R. Martins, and S. Knapp, Accumulating evidence for a role of oxidized phospholipids in infectious diseases. Cell Mol Life Sci, 2015. 72(6): p. 1059-71.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25410378
2015
Schliehe, C., E.K. Flynn, B. Vilagos, U. Richson, S. Swaminathan, B. Bosnjak, L. Bauer, R.K. Kandasamy, I.M. Griesshammer, L. Kosack, F. Schmitz, V. Litvak, J. Sissons, A. Lercher, A. Bhattacharya, K. Khamina, A.L. Trivett, L. Tessarollo, I. Mesteri, A. Hladik, D. Merkler, S. Kubicek, S. Knapp, M.M. Epstein, D.E. Symer, A. Aderem, and A. Bergthaler, The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection. Nat Immunol, 2015. 16(1): p. 67-74.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25419628
2016
Castiglia, V., A. Piersigilli, F. Ebner, M. Janos, O. Goldmann, U. Dambock, A. Kroger, S. Weiss, S. Knapp, A.M. Jamieson, C. Kirschning, U. Kalinke, B. Strobl, M. Muller, D. Stoiber, S. Lienenklaus, and P. Kovarik, Type I Interferon Signaling Prevents IL-1beta-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue. Cell Host Microbe, 2016. 19(3): p. 375-87.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26962946
2016
Knapp, S., Gut to lung. Gut, 2016. 65(4): p. 544-5.
Abstract: http://gut.bmj.com/content/65/4/544
2016
Willmann KL, Sacco R, Martins R, Garncarz W, Krolo A, Knapp S, Bennett KL, Boztug K. Expanding the Interactome of the Noncanonical NF-_B Signaling Pathway. J Proteome Res. 2016 Sep 2;15(9):2900-9. doi: 10.1021/acs.jproteome.5b01004.
Abstract: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295629/
2016
Sibilano R, Gaudenzio N, DeGorter MK, Reber LL, Hernandez JD, Starkl PM, Zurek OW, Tsai M, Zahner S, Montgomery SB, Roers A, Kronenberg M, Yu M, Galli SJ. A TNFRSF14-Fc_RI-mast cell pathway contributes to development of multiple features of asthma pathology in mice. Nat Commun. 2016 Dec 16;7:13696. doi: 10.1038/ncomms13696.
Abstract: http://www.nature.com/articles/ncomms13696
2016
Reber LL, Gaudenzio N, Starkl P, Galli SJ. Neutrophils are not required for resolution of acute gouty arthritis in mice. Nat Med. 2016 Dec 6;22(12):1382-1384. doi: 10.1038/nm.4216.
Abstract: http://www.nature.com/nm/journal/v22/n12/full/nm.4216.html
2016
Mukai K, Tsai M, Starkl P, Marichal T, Galli SJ. IgE and mast cells in host defense against parasites and venoms. Semin Immunopathol. 2016 Sep;38(5):581-603. doi: 10.1007/s00281-016-0565-1. Review.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/27225312
2016
Martins R, Maier J, Gorki AD, Huber KV, Sharif O, Starkl P, Saluzzo S, Quattrone F, Gawish R, Lakovits K, Aichinger MC, Radic-Sarikas B, Lardeau CH, Hladik A, Korosec A, Brown M, Vaahtomeri K, Duggan M, Kerjaschki D, Esterbauer H, Colinge J, Eisenbarth SC, Decker T, Bennett KL, Kubicek S, Sixt M, Superti-Furga G, Knapp S. Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions. Nat Immunol. 2016 Oct 31. doi: 10.1038/ni.3590.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/27798618
2016
Maier BB, Hladik A, Lakovits K, Korosec A, Martins R, Kral JB, Mesteri I, Strobl B, Müller M, Kalinke U, Merad M, Knapp S. Type I interferon promotes alveolar epithelial type II cell survival during pulmonary Streptococcus pneumoniae infection and sterile lung injury in mice. Eur J Immunol. 2016 Sep;46(9):2175-86. doi: 10.1002/eji.201546201.
Abstract: http://onlinelibrary.wiley.com/doi/10.1002/eji.201546201/abstract
2016
Kral JB, Kuttke M, Schrottmaier WC, Birnecker B, Warszawska J, Wernig C, Paar H, Salzmann M, Sahin E, Brunner JS, Österreicher C, Knapp S, Assinger A, Schabbauer G. Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways. Sci Rep. 2016 Mar 14;6:23034. doi: 10.1038/srep23034.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/26971883
2016
Doehn JM, Winkler A, Kuzmina Z, Hladik A, Greinix H, Knapp S, Robak O. Pentraxin-3 levels in graft-versus-host disease during allogeneic hematopoietic stem cell transplantation. Exp Hematol. 2016 Jul 9. pii: S0301-472X(16)30460-X.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/27403536
2015
Prochazkova J, Sakaguchi S, Owusu M, Mazouzi A, Wiedner M, Velimezi G, Moder M, Turchinovich G, Hladik A, Gurnhofer E, Hayday A, Behrens A, Knapp S, Kenner L, Ellmeier W, Loizou JI. DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation. PLoS Genet. 2015 Nov 6;11(11):e1005645. doi: 10.1371/journal.pgen.1005645. eCollection 2015.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/26544571
2015
Blatt K, Cerny-Reiterer S, Schwaab J, Sotlar K, Eisenwort G, Stefanzl G, Hoermann G, Mayerhofer M, Schneeweiss M, Knapp S, Rülicke T, Hadzijusufovic E, Bauer K, Smiljkovic D, Willmann M, Reiter A, Horny HP, Valent P. Identification of the Ki-1 antigen (CD30) as a novel therapeutic target in systemic mastocytosis. Blood. 2015 Oct 20. pii: blood-2015-03-637728.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/26486787
2015
Kulinski TM, Casari MR, Guenzl PM, Wenzel D, Andergassen D, Hladik A, Datlinger P, Farlik M, Theussl HC, Penninger JM, Knapp S, Bock C, Barlow DP, Hudson QJ. Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern. Dev Biol. 2015 Jun 15;402(2):291-305. doi: 10.1016/j.ydbio.2015.04.010. Epub 2015 Apr 24.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25912690
2015
Heinz LX, Baumann CL, Köberlin MS, Snijder B, Gawish R, Shui G, Sharif O, Aspalter IM, Müller AC, Kandasamy RK, Breitwieser FP, Pichlmair A, Bruckner M, Rebsamen M, Blüml S, Karonitsch T, Fauster A, Colinge J, Bennett KL, Knapp S, Wenk MR, Superti-Furga G. The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity. Cell Rep. 2015 Jun 30;11(12):1919-28. doi: 10.1016/j.celrep.2015.05.006.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/26095358
2014
Sharif O, Gawish R, Warszawska JM, Martins R, Lakovits K, Hladik A, Doninger B, Brunner J, Korosec A, Schwarzenbacher RE, Berg T, Kralovics R, Colinge J, Mesteri I, Gilfillan S, Salmaggi A, Verschoor A, Colonna M, Knapp S. The triggering receptor expressed on myeloid cells 2 inhibits complement component 1q effector mechanisms and exerts detrimental effects during pneumococcal pneumonia. PLoS Pathog. 2014 Jun 12;10(6):e1004167. doi: 10.1371/journal.ppat.1004167. eCollection 2014.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24945405
2014
Köffel R, Meshcheryakova A, Warszawska J, Hennig A, Wagner K, Jörgl A, Gubi D, Moser D, Hladik A, Hoffmann U, Fischer MB, van den Berg W, Koenders M, Scheinecker C, Gesslbauer B, Knapp S, Strobl H. Monocytic cell differentiation from band-stage neutrophils under inflammatory conditions via MKK6 activation. Blood. 2014 Sep 11. pii: blood-2014-07-588178.[Epub ahead of print]
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25214442
2014
Jais A, Einwallner E, Sharif O, Gossens K, Lu TT, Soyal SM, Medgyesi D, Neureiter D, Paier-Pourani J, Dalgaard K, Duvigneau JC, Lindroos-Christensen J, Zapf TC, Amann S, Saluzzo S, Jantscher F, Stiedl P, Todoric J, Martins R, Oberkofler H, Müller S, Hauser-Kronberger C, Kenner L, Casanova E, Sutterlüty-Fall H, Bilban M, Miller K, Kozlov AV, Krempler F, Knapp S, Lumeng CN, Patsch W, Wagner O, Pospisilik JA, Esterbauer H. Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man. Cell. 2014 Jul 3;158(1):25-40. doi: 10.1016/j.cell.2014.04.043.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24995976
2013
Bürckstümmer T, Banning C, Hainzl P, Schobesberger R, Kerzendorfer C, Pauler FM, Chen D, Them N, Schischlik F, Rebsamen M, Smida M, Fece de la Cruz F, Lapao A, Liszt M, Eizinger B, Guenzl PM, Blomen VA, Konopka T, Gapp B, Parapatics K, Maier B, Stöckl J, Fischl W, Salic S, Taba Casari MR, Knapp S, Bennett KL, Bock C, Colinge J, Kralovics R, Ammerer G, Casari G, Brummelkamp TR, Superti-Furga G, Nijman SM. A reversible gene trap collection empowers haploid genetics in human cells. Nat Methods. 2013 Oct;10(10):965-71.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24161985
2013
Sharif O, Matt U, Saluzzo S, Lakovits K, Haslinger I, Furtner T, Doninger B, Knapp S. The scavenger receptor CD36 downmodulates the early inflammatory response while enhancing bacterial phagocytosis during pneumococcal pneumonia.J Immunol. 2013 Jun 1;190(11):5640-8. doi: 10.4049/jimmunol.1202270. Epub 2013 Apr 22.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23610144
2013
Zielinski C, Knapp S, Mascaux C, Hirsch F. Rationale for targeting the immune system through checkpoint molecule blockade in the treatment of non-small-cell lung cancer. Ann Oncol. 2013 May; 24(5): 1170–1179.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23393121
2013
Warszawska JM, Gawish R, Sharif O, Sigel S, Doninger B, Lakovits K, Mesteri I, Nairz M, Boon L, Spiel A, Fuhrmann V, Strobl B, Müller M, Schenk P, Weiss G, Knapp S. Lipocalin 2 deactivates macrophages and worsens pneumococcal pneumonia outcomes. J Clin Invest. 2013 August 1; 123(8).
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23863624
2013
Matt U, Sharif O, Martins R, Furtner T, Langeberg L, Gawish R, Elbau I, Zivkovic A, Lakovits A, Oskolkova O, Doninger B, Vychytil A, Perkmann T, Schabbauer G, Binder CJ, Bochkov VN, Scott JD, Knapp S. WAVE1 mediates suppression of phagocytosis by phospholipid-derived DAMPs. J Clin Invest. 2013 July 1; 123(7): 3014–3024. .
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23934128
2012
Sigel S, Bunk S, Meergans T, Doninger B, Stich K, Stulnig T, Derfler K, Hoffmann J, Deininger S, von Aulock S, Knapp S. Apolipoprotein B100 is a suppressor of Staphylococcus aureus-induced innate immune response in humans and mice. Eur J Immunol. 2012 Jul 18. doi: 10.1002/eji.201242564. [Epub ahead of print].
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22806614
2012
Knapp S. Animal Models of Sepsis. Section Editor of this issue and Editorial. Drug Discovery Today – Disease Models Jan 2012.
2011
Zivkovic A, Sharif O, Stich K, Doninger B, Biaggio M, Colinge J, Bilban M, Mesteri I, Hazemi P, Lemmens-Gruber R, Knapp S. TLR 2 and CD14 mediate innate immunity and lung inflammation to staphylococcal Panton-Valentine leukocidin in vivo. J Immunol. 2011 Feb 1;186(3):1608-17.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21178007
2011
Gratz N, Hartweger H, Matt U, Kratochvill F, Janos M, Sigel S, Drobits B, Li XD, Knapp S, Kovarik P. Type I interferon production induced by Streptococcus pyogenes-derived nucleic acids is required for host protection. PLoS Pathog. 2011 May;7(5):e1001345.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21625574
2010
Schabbauer G, Matt U, Gunzl P, Warszawska J, Furtner T, Hainzl E, Elbau I, Mesteri I, Doninger B, Binder BR, Knapp S. Myeloid PTEN promotes inflammation but impairs bactericidal activities during murine pneumococcal pneumonia. J Immunol. 2010 Jul 1;185(1):468-76. Epub 2010 May 26.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20505137
2010
Radwan M, Stiefvater R, Gruner T, Sharif O, Miller I, Marchetti-Deschmann M, Allmaier G, Gemeiner M, Knapp S, Kovarik P, Muller M, Strobl B. Tyrosine kinase 2 controls interleukin-1 production at the translational level. J Immunol. 2010 Sep 15;185(6):3544-53. Epub 2010 Aug 16.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20713887
2010
Knapp S. Update on the role of Toll-like receptors during bacterial infections and sepsis. Wien Med Wochenschr. 2010 Mar;160(5-6):107-11.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20364412
2010
Knapp S, Frass M. Editorial: Sepsis. Wien Med Wochenschr. 2010 Mar;160(5-6):105-6.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20364411
2010
Guenzl P, Hainzl E, Matt U, Dillinger B, Mahr B, Knapp S, Binder BR, Schabbauer G. Anti-inflammatory properties of the phosphoinositide- 3 kinase (PI3K) pathway are mediated by IL- 10/DUSP regulation. J Leukoc Biol. J Leukoc Biol. 2010 Dec;88(6):1259-69. Epub 2010 Sep 30.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20884649
2010
Bunk S, Sigel S, Metzdorf D, Sharif O, Triantafilou K, Triantafilou M, Hartung T, Knapp S, von Aulock S. Internalization and coreceptor expression are critical for TLR2-mediated recognition of lipoteichoic acid in human peripheral blood. J Immunol. 2010 Sep 15;185(6):3708-17. Epub 2010 Aug 16.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20713893
2010
Boucheron N, Sharif O, Schebesta A, Croxford A, Raberger J, Schmidt U, Vigl B, Bauer J, Bankoti R, Lassmann H, Epstein MM, Knapp S, Waisman A, Ellmeier W. The protein tyrosine kinase Tec regulates a CD44hiCD62L-Th17 subset. J Immunol. 2010 Nov 1;185(9):5111-9. Epub 2010 Sep 24.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20870948
2010
Baumann CL, Aspalter IM, Sharif O, Pichlmair A, Bluml S, Grebien F, Bruckner M, Pasierbek P, Aumayr K, Planyavsky M, Bennett KL, Colinge J, Knapp S, Superti-Furga G. CD14 is a co-receptor of Toll-like receptors 7 and 9. J Exp Med. 2010 Nov 22;207(12):2689-701. Epub 2010 Nov 15.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21078886
2009
von Schlieffen E, Oskolkova OV, Schabbauer G, Gruber F, Blüml S, Genest M, Kadl A, Marsik C, Knapp S, Chow J, Leitinger N, Binder BR, Bochkov VN. Multi-hit inhibition of circulating and cell-associated components of the toll-like receptor 4 pathway by oxidized phospholipids. Arterioscler Thromb Vasc Biol, 2009 Mar; 29(3):356-62. Epub 2008 Dec 26.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19112167
2009
Moser C, Pohl G, Haslinger I, Knapp S, Rowczenio D, Russel T, Lachmann HJ, Lang U, Kovarik J. Successful treatment of familial Mediterranean fever with Anakinra and outcome after renal transplantation. Nephrol Dial Transplant, 2009 Feb;24(2):676-8.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19033248
2009
Matt U, Warszawska JM, Bauer M, Dietl W, Mesteri I, Haslinger I, Schabbauer G, Perkmann T, Binder CJ, Reingruber S, Petzelbauer P, Knapp S. B15-42 protects against acid-induced acute lung injury and secondary Pseudomonas pneumonia in vivo. Am J Respir Crit Care Med, 2009 Dec;180(12):1208-17. Epub 2009 Sep 17.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19762562
2009
Lagler H, Sharif O, Haslinger I, Matt U, Stich K, Furtner T, Doninger B, Schmid K, Gattringer R, de Vos AF, Knapp S. TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia. J Immunol, 2009 Aug;183(3): 2027-36. Epub 2009 Jul 13.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19596984
2009
Gröger M, Pasteiner W, Ignatyev G, Matt U, Knapp S, Atrasheuskaya A, Bukin E, Friedl P, Zinkl D, Hofer-Warbinek R, Zacharowski K, Petzelbauer P, Reingruber S. Peptide Bbeta (15-42) preserves endothelial barrier function in shock. PLoS ONE, 2009;4(4): e5391. Epub 2009 Apr 29.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19401765
2008
Sharif O, Knapp S. From expression to signaling: Roles of TREM-1 and TREM-2 in innate immunity and bacterial infection. Immunobiology 2008, 213, 701–713.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/18926286
2008
Knapp S, von Aulock S, Leendertse M, Haslinger I, Draing C, Golenbock DT, van der Poll T. Lipoteichoic Acid-induced Lung Inflammation depends on TLR2 and the concerted action of TLR4 and Platelet-activating Factor Receptor. Journal of Immunology 2008, 180: 3478–3484.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/18292574
2008
Filippakopoulos P, Kofler M, Hantschel O, Gish GD, Grebien F, Salah E, Neudecker P, Kay LE, Turk BE, Superti-Furga G, Pawson T, Knapp S. Structural coupling of Fes and Abl SH2-tyrosine kinase domains links substrate recognition and kinase activation. Cell. 2008 Sep 5;134(5): 793–803.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/18775312
2007
Knapp S. Innate recognition of bacteria. Expert Rev Clin Immunol. 2007, 3:443–445 (Editorial).
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20477147
2007
Knapp S, Matt U, Leitinger N, van der Poll T. Oxidized phospholipids inhibit phagocytosis and impair outcome in gram-negative sepsis in vivo. J Immunol. 2007, 178:993–1001.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/17202362
2007
Gattringer R, Lagler H, Gattringer KB, Knapp S, Burgmann H, et al. Anakinra in two adolescent female patients suffering from colchicineresistant familial Mediterranean fever: effective but risky. Eur J Clin Invest. 2007, 37:912–914.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/17973784
2007
Dessing M, Knapp S, Florquin S, de Vos AF, van der Poll T. CD14 facilitates invasive respiratory tract infections by Streptococcus pneumoniae. Am J Respir Crit Care Med. 2007, 175:604–611. 
Abstract: http://www.atsjournals.org/doi/full/10.1164/rccm.200606-824OC#.UrGhL-JHLcY