2017
Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity.
Li J,
Casteels T,
Frogne T,
Ingvorsen C,
Honoré C,
Courtney M,
Huber KV,
Schmitner N,
Kimmel RA,
Romanov RA,
Sturtzel C,
Lardeau CH,
Klughammer J,
Farlik M,
Sdelci S,
Vieira A,
Avolio F,
Briand F,
Baburin I,
Májek P,
Pauler FM,
Penz T,
Stukalov A,
Gridling M,
Parapatics K,
Barbieux C,
Berishvili E,
Spittler A,
Colinge J,
Bennett KL,
Hering S,
Sulpice T,
Bock C,
Distel M,
Harkany T,
Meyer D,
Superti-Furga G,
Collombat P,
Hecksher-Sørensen J,
Kubicek S.
Cell. 2017 Jan 12;168(1-2):86-100.e15. doi: 10.1016/j.cell.2016.11.010. Epub 2016 Dec 1.
2017
A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor.
Licciardello MP,
Ringler A,
Markt P,
Klepsch F,
Lardeau CH,
Sdelci S,
Schirghuber E,
Müller AC,
Caldera M,
Wagner A,
Herzog R,
Penz T,
Schuster M,
Boidol B,
Dürnberger G,
Folkvaljon Y,
Stattin P,
Ivanov V,
Colinge J,
Bock C,
Kratochwill K,
Menche J,
Bennett KL,
Kubicek S.
Nat Chem Biol. 2017 Jul;13(7):771-778. doi: 10.1038/nchembio.2382. Epub 2017 May 22.
2015
NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation.
Licciardello MP,
Müllner MK,
Dürnberger G,
Kerzendorfer C,
Boidol B,
Trefzer C,
Sdelci S,
Berg T,
Penz T,
Schuster M,
Bock C,
Kralovics R,
Superti-Furga G,
Colinge J,
Nijman SM,
Kubicek S.
Oncogene. 2015 Jul;34(29):3780-90. doi: 10.1038/onc.2014.319. Epub 2014 Sep 29.
2015
Proteome-wide drug and metabolite interaction mapping by thermal-stability profiling.
Huber KV,
Olek KM,
Müller AC,
Tan CS,
Bennett KL,
Colinge J,
Superti-Furga G.
Nat Methods. 2015 Nov;12(11):1055-7. doi: 10.1038/nmeth.3590. Epub 2015 Sep 21.
2015
A surface biotinylation strategy for reproducible plasma membrane protein purification and tracking of genetic and drug-induced alterations.
Hörmann K,
Stukalov A,
Müller AC,
Heinz LX,
Superti-Furga G,
Colinge J,
Bennett KL.
J Proteome Res. 2015 Dec 24.
2015
Germline RBBP6 mutations in familial myeloproliferative neoplasms.
Harutyunyan AS,
Giambruno R,
Krendl C,
Stukalov A,
Klampfl T,
Berg T,
Chen D,
Milosevic Feenstra JD,
Jäger R,
Gisslinger B,
Gisslinger H,
Rumi E,
Passamonti F,
Pietra D,
Müller AC,
Parapatics K,
Breitwieser FP,
Herrmann R,
Colinge J,
Bennett KL,
Superti-Furga G,
Cazzola M,
Hammond E,
Kralovics R.
Blood. 2015 Nov 16. pii: blood-2015-09-668673.
2015
Gene essentiality and synthetic lethality in haploid human cells.
Blomen VA,
Májek P,
Jae LT,
Bigenzahn JW,
Nieuwenhuis J,
Staring J,
Sacco R,
van Diemen FR,
Olk N,
Stukalov A,
Marceau C,
Janssen H,
Carette JE,
Bennett KL,
Colinge J,
Superti-Furga G,
Brummelkamp TR.
Science. 2015 Nov 27;350(6264):1092-6. doi: 10.1126/science.aac7557. Epub 2015 Oct 15.
2015
Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage.
Bhattacharya A,
Hegazy AN,
Deigendesch N,
Kosack L,
Cupovic J,
Kandasamy RK,
Hildebrandt A,
Merkler D,
Kühl AA,
Vilagos B,
Schliehe C,
Panse I,
Khamina K,
Baazim H,
Arnold I,
Flatz L,
Xu HC,
Lang PA,
Aderem A,
Takaoka A,
Superti-Furga G,
Colinge J,
Ludewig B,
Löhning M,
Bergthaler A.
Immunity. 2015 Nov 17;43(5):974-86. doi: 10.1016/j.immuni.2015.10.013.
2015
Targeting a cell state common to triple-negative breast cancers.
Muellner MK,
Mair B,
Ibrahim Y,
Kerzendorfer C,
Lechtermann H,
Trefzer C,
Klepsch F,
Müller AC,
Leitner E,
Macho-Maschler S,
Superti-Furga G,
Bennett KL,
Baselga J,
Rix U,
Kubicek S,
Colinge J,
Serra V,
Nijman SM.
Mol Syst Biol. 2015 Feb 19;11(1):789. doi: 10.15252/msb.20145664.
2014
TOPS: a versatile software tool for statistical analysis and visualization of combinatorial gene-gene and gene-drug interaction screens.
Muellner MK,
Duernberger G,
Ganglberger F,
Kerzendorfer C,
Uras IZ,
Schoenegger A,
Bagienski K,
Colinge J,
Nijman SM.
BMC Bioinformatics. 2014 Apr 8;15:98. doi: 10.1186/1471-2105-15-98.
