Publications
2023
Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet
Mathilde Meyenberg,
Anna Hakobyan,
Nikolina Papac-Milicevic,
Laura Göderle,
Franziska L Langner,
Mateo Markovic,
Ji-Hyun Lee,
Bon-Kyoung Koo,
Georg A Busslinger,
Israel Tojal da Silva,
Christoph J Binder,
Jörg Menche,
Joanna I Loizou.
Sci Rep. 2023 Aug 26;13(1):13964. doi: 10.1038/s41598-023-41123-3.
2023
Cell-autonomous regulation of complement C3 by factor H limits macrophage efferocytosis and exacerbates atherosclerosis
Máté G Kiss,
Nikolina Papac-Miličević,
Florentina Porsch,
Dimitrios Tsiantoulas,
Tim Hendrikx,
Minoru Takaoka,
Huy Q Dinh,
Marie-Sophie Narzt,
Laura Göderle,
Mária Ozsvár-Kozma,
Michael Schuster,
Nikolaus Fortelny,
Anastasiya Hladik,
Sylvia Knapp,
Florian Gruber,
Matthew C Pickering,
Christoph Bock,
Filip K Swirski,
Klaus Ley,
Alma Zernecke,
Clément Cochain,
Claudia Kemper,
Ziad Mallat,
Christoph J Binder.
Immunity. 2023 Aug 8;56(8):1809-1824.e10. doi: 10.1016/j.immuni.2023.06.026. Epub 2023 Jul 26.
2021
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation.
Niyonzima N,
Rahman J,
Kunz N,
West EE,
Freiwald T,
Desai JV,
Merle NS,
Gidon A,
Sporsheim B,
Lionakis MS,
Evensen K,
Lindberg B,
Skagen K,
Skjelland M,
Singh P,
Haug M,
Ruseva MM,
Kolev M,
Bibby J,
Marshall O,
O'Brien B,
Deeks N,
Afzali B,
Clark RJ,
Woodruff TM,
Pryor M,
Yang ZH,
Remaley AT,
Mollnes TE,
Hewitt SM,
Yan B,
Kazemian M,
Kiss MG,
Binder CJ,
Halvorsen B,
Espevik T,
Kemper C.
Sci Immunol. 2021 Dec 24;6(66):eabf2489. doi: 10.1126/sciimmunol.abf2489. Epub 2021 Dec 24.
2021
APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans.
Tsiantoulas D,
Eslami M,
Obermayer G,
Clement M,
Smeets D,
Mayer FJ,
Kiss MG,
Enders L,
Weißer J,
Göderle L,
Lambert J,
Frommlet F,
Mueller A,
Hendrikx T,
Ozsvar-Kozma M,
Porsch F,
Willen L,
Afonyushkin T,
Murphy JE,
Fogelstrand P,
Donzé O,
Pasterkamp G,
Hoke M,
Kubicek S,
Jørgensen HF,
Danchin N,
Simon T,
Scharnagl H,
März W,
Borén J,
Hess H,
Mallat Z,
Schneider P,
Binder CJ.
Nature. 2021 Sep;597(7874):92-96. doi: 10.1038/s41586-021-03818-3. Epub 2021 Aug 25.
2022
Tim-1 mucin domain-mutant mice display exacerbated atherosclerosis
Hidde Douna,
Virginia Smit,
Gijs H M van Puijvelde,
Mate G Kiss,
Christoph J Binder,
Llze Bot,
Vijay K Kuchroo,
Andrew H Lichtman,
Johan Kuiper,
Amanda C Foks.
Atherosclerosis. 2022 Jul;352:1-9. doi: 10.1016/j.atherosclerosis.2022.05.017. Epub 2022 May 21.
2022
IFNγ-Stimulated B Cells Inhibit T Follicular Helper Cells and Protect Against Atherosclerosis
Hidde Douna,
J de Mol,
Jacob Amersfoort,
Frank H Schaftenaar,
Mate G Kiss,
Bianca E Suur,
Mara J Kroner,
Christoph J Binder,
Ilze Bot,
Gijs H M Van Puijvelde,
Johan Kuiper,
Amanda C Foks.
Front Cardiovasc Med. 2022 Feb 2;9:781436. doi: 10.3389/fcvm.2022.781436. eCollection 2022.
2021
Natural IgM antibodies inhibit microvesicle-driven coagulation and thrombosis.
Obermayer G,
Afonyushkin T,
Göderle L,
Puhm F,
Schrottmaier W,
Taqi S,
Schwameis M,
Ay C,
Pabinger I,
Jilma B,
Assinger A,
Mackman N,
Binder C.
Blood
2020
Ikk2-mediated inflammatory activation of arterial endothelial cells promotes the development and progression of atherosclerosis.
Mussbacher M,
Salzmann M,
Haigl B,
Basílio J,
Hochreiter B,
Gleitsmann V,
Moser B,
Hoesel B,
Suur BE,
Puhm F,
Ungerböck C,
Kuttke M,
Forteza MJ,
Binder CJ,
Ketelhuth DFJ,
Assinger A,
Schmid JA.
Atherosclerosis. 2020 Aug;307:21-31. doi: 10.1016/j.atherosclerosis.2020.06.005. Epub 2020 Jul 6.
2020
The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity.
Salzer E,
Zoghi S,
Kiss MG,
Kage F,
Rashkova C,
Stahnke S,
Haimel M,
Platzer R,
Caldera M,
Ardy RC,
Hoeger B,
Block J,
Medgyesi D,
Sin C,
Shahkarami S,
Kain R,
Ziaee V,
Hammerl P,
Bock C,
Menche J,
Dupré L,
Huppa JB,
Sixt M,
Lomakin A,
Rottner K,
Binder CJ,
Stradal TEB,
Rezaei N,
Boztug K.
Sci Immunol. 2020 Jul 10;5(49):eabc3979. doi: 10.1126/sciimmunol.abc3979.
2020
Formation of atherosclerotic lesions is independent of eosinophils in male mice.
Hofheinz K,
Seibert F,
Ackermann JA,
Dietel B,
Tauchi M,
Oszvar-Kozma M,
Kühn H,
Schett G,
Binder CJ,
Krönke G.
Atherosclerosis. 2020 Oct;311:67-72. doi: 10.1016/j.atherosclerosis.2020.08.030. Epub 2020 Sep 8.
