Adjunct PIs
| Year | Paper |
|---|---|
| 2011 | Carette JE, Guimaraes CP, Wuethrich I, Blomen VA, Varadarajan M, Sun C, Bell G, Yuan B, Muellner MK, Nijman SM, Ploegh HL, Brummelkamp TR. Global gene disruption in human cells to assign genes to phenotypes by deep sequencing. Nat Biotechnol. 2011 Jun;29(6):542-6. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21623355 |
| 2014 | Jae LT, Raaben M, Herbert AS, Kuehne AI, Wirchnianski AS, Soh TK, Stubbs SH, Janssen H, Damme M, Saftig P, Whelan SP, Dye JM, Brummelkamp TR. Virus entry. Lassa virus entry requires a trigger-induced receptor switch. Science. 2014 Jun 27;344(6191):1506-10. doi: 10.1126/science.1252480. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24970085 |
| 2015 | Blomen VA, Májek P, Jae LT, Bigenzahn JW, Nieuwenhuis J, Staring J, Sacco R, van Diemen FR, Olk N, Stukalov A, Marceau C, Janssen H, Carette JE, Bennett KL, Colinge J, Superti-Furga G, Brummelkamp TR. Gene essentiality and synthetic lethality in haploid human cells. Science. 2015 Nov 27;350(6264):1092-6. doi: 10.1126/science.aac7557. Epub 2015 Oct 15. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/26472760 |
| 2017 | Raaben M, Jae LT, Herbert AS, Kuehne AI, Stubbs SH, Chou YY, Blomen VA, Kirchhausen T, Dye JM, Brummelkamp TR, Whelan SP. NRP2 and CD63 Are Host Factors for Lujo Virus Cell Entry.Cell Host Microbe. 2017 Nov 8;22(5):688-696.e5. doi: 10.1016/j.chom.2017.10.002. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29120745 |
| 2017 | Loregger A, Raaben M, Tan J, Scheij S, Moeton M, van den Berg M, Gelberg-Etel H, Stickel E, Roitelman J, Brummelkamp T, Zelcer N. Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis. Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):2064-2074. doi: 10.1161/ATVBAHA.117.310002. Epub 2017 Sep 7. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28882874 |
| 2017 | Mezzadra R, Sun C, Jae LT, Gomez-Eerland R, de Vries E, Wu W, Logtenberg MEW, Slagter M, Rozeman EA, Hofland I, Broeks A, Horlings HM, Wessels LFA, Blank CU, Xiao Y, Heck AJR, Borst J, Brummelkamp TR, Schumacher TNM. Identification of CMTM6 and CMTM4 as PD-L1 protein regulators. Nature. 2017 Sep 7;549(7670):106-110. doi: 10.1038/nature23669. Epub 2017 Aug 16. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28813410 |
| 2017 | Brockmann M, Blomen VA, Nieuwenhuis J, Stickel E, Raaben M, Bleijerveld OB, Altelaar AFM, Jae LT, Brummelkamp TR. Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling. Nature. 2017 Jun 8;546(7657):307-311. doi: 10.1038/nature22376. Epub 2017 May 31. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28562590 |
| 2017 | Staring J, von Castelmur E, Blomen VA, van den Hengel LG, Brockmann M, Baggen J, Thibaut HJ, Nieuwenhuis J, Janssen H, van Kuppeveld FJ, Perrakis A, Carette JE, Brummelkamp TR. PLA2G16 represents a switch between entry and clearance of Picornaviridae. Nature. 2017 Jan 19;541(7637):412-416. doi: 10.1038/nature21032. Epub 2017 Jan 11. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28077878 |
| 2018 | Staring J, van den Hengel LG, Raaben M, Blomen VA, Carette JE, Brummelkamp TR. KREMEN1 Is a Host Entry Receptor for a Major Group of Enteroviruses. Cell Host Microbe. 2018 May 9;23(5):636-643.e5. doi: 10.1016/j.chom.2018.03.019. Epub 2018 Apr 19. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29681460 |