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2nd REsolution Consortium Meeting


Project partners at the 2nd REsolution Consortium Meeting at CeMM (© Laura Alvarez / CeMM).

On 20 June 2022, the REsolution consortium held its second consortium meeting, which was the first one in person since the project started. The event took place at CeMM with 20 participants coming from different countries. The REsolution consortium is a public-private research partnership supported by the Innovative Medicines Initiative (IMI), the European Union and EFPIA, with nine partners from academia and the pharmaceutical industry. With a duration of two years, the project aims at understanding how genetic variants in humans affect the function of cellular solute carrier transporters (SLCs).

REsolution scientists summarized the data generated on the collection and annotation of human genetic variants for SLCs and associated phenotypes. They also re-aligned on the strategies to characterize selected variants and perform deep mutational scanning studies on SLCs involved in human diseases. Finally, they discussed the interpretation of variant effects based on structural and functional information and compared to predicted effects by Variant Effect Predictors.

We would like to thank all participants for joining the meeting and specially the speakers for their excellent presentations.

For more information, please visit and follow the project on Twitter at @RESOLUTE_IMI.