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Professor Michael Wakelam in the lipidomics facility at the Babraham Institute. Image used courtesy of Keith Heppell and the Cambridge Independent.

Obituary Michael Wakelam

The CeMM community was shocked to hear the tragic news of the passing of Michael Wakelam, Director of The Babraham Institute, Cambridge, U.K.


Since the foundation of the EU-Life Alliance, he was committed to building a community of excellence and promoting science. We will remember him from his visits to CeMM and collaborating with him at EU-Life meetings. Those who met him, even briefly, will remember him as friendly and open, always available for a chat or an in-depth discussion.  His dedication to The Babraham, to EU-Life, to science and science education was immense. His loss will be deeply felt across the European science community.


O…

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RNA sample preparation and genome sequencing at CeMM / © CeMM

Mutational Dynamics of SARS-CoV-2 in Austria

As a leading biomedical research institute, CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, is committed to advancing our molecular understanding of the COVID-19 pandemic and the causative pathogen, SARS-CoV-2. Biomedical research on the virus and the disease will contribute substantially to informed policy decisions and, ultimately, the development of new treatments.

An interdisciplinary team at CeMM under the project leadership of virologist Andreas Bergthaler and computational biologist Christoph Bock will investigate SARS-CoV-2 genome evolution in patients by deep sequencing and sophisticated…

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CeMM events and seminars postponed

Due to the latest developments in the corona virus (COVID-19) and as a preventive health measure, CeMM has decided to cancel all public events and seminars until 13 April 2020. Events will be rescheduled to a later date.

Please check the CeMM website where the new dates will be announced.

Should you have any questions, do not hesitate to contact us at info@cemm.at

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Last author Giulio Superti-Furga and first author Enrico Girardi (© Klaus Pichler / CeMM)

Uncovering novel relationships between solute carrier transporters and cytotoxic drugs in human cells

Researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences have studied how Solute Carriers (SLCs), a large family of membrane transport proteins, influence the activity and potency of cytotoxic drugs, such as those used in the treatment of leukemia and other cancers. Their study, published in the journal Nature Chemical Biology, uncovers the dependency of most drugs studied on the function of at least one SLC. In some cases, the drug required the transporter to enter into the cell, in other cases, it provided small molecules (metabolites), which are crucial to the drug’s activity or the cell response…

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Participants at the AustroVirology Symposium 2020 | Photo credit: CeMM / CCRI

AustroVirology Symposium 2020

On 5 March 2020, the first AustroVirology Symposium took place at the St. Anna Kinderkrebsforschung (CCRI) in Vienna. The event, organized by CeMM PI Andreas Bergthaler and Karin Kosulin (CCRI), brought together 75 virologists from 12 institutions across Austria. The goal was to capture the rich diversity of academic, clinical and industrial virological research and to provide a platform to meet colleagues and forge new collaborations in the field.

The symposium kicked off by an inspiring keynote lecture about the co-evolution of phages and bacteria by Martin Polz, Professor at the Massachusetts Institute of Technology (MIT) and the…

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Kaan Boztug, CeMM Adjunct PI and LBI-RUD Director | Photo credit: Klaus Pichler / CeMM

Rare Disease Day 2020

Today is Rare Diseases Day, which takes place every four years on 29 February. Currently 400 million people worldwide, of whom 30 million are in Europe[i] and 400,000 in Austria, are affected by a rare disease. There are between 5,000 and 8,000 different rare diseases[ii], and the vast majority are caused by a single genetic defect, which can already be detected in early childhood. They are not as uncommon as we may think but they are so little widespread that those who are affected by them are often not properly diagnosed or do not receive the most appropriate treatment for their condition.

Developing more effective and appropriate…

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Co-first authors André Rendeiro and Thomas Krausgruber with co-last author Christoph Bock (© Klaus Pichler/CeMM)

Single-cell sequencing of leukemia therapy: Shared genetic program, patient-specific execution

Researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, the Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases in Vienna, the University Medical Center of Regensburg, and the National Institute of Hematology and Infectious Diseases and the Semmelweis University in Budapest have studied the response to targeted leukemia therapy in unprecedented detail, using single-cell sequencing and epigenetic analysis. The paper published in the journal Nature Communications uncovers a precise molecular program in patients with chronic lymphocytic leukemia (CLL) who start treatment with the targeted…

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CeMM International PhD Program Call Open

The next PhD Program of CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna will start in September 2020. We are offering 15 fully funded PhD positions at CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, and LBI-RUD, the Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases.

•    Do you want to work in an environment that promotes free-minded scientific creativity, and translate your findings to impact medical practice and improve healthcare?
•    Are you excited to gain a new understanding of the molecular physiology and pathology of humans?
•    Do you…

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From L to R: Mark P. Petronczki (Boehringer Ingelheim), Simon Wöhrle (Boehringer Ingelheim), Sandra Schick (CeMM), Stefan Kubicek (CeMM), Brian R. Cairns (University of Utah) and Georg Casari (Haplogen) (© Laura Alvarez/CeMM)

Christian Doppler Laboratory Closing Symposium

From 15 to 17 January 2020, the Christian Doppler Laboratory Closing Symposium “From Understanding Chromatin Dynamics to Therapeutics Targeting will take place at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna (Austria). The event is jointly organized by CeMM PI Stefan Kubicek, CeMM PostDoc Sandra Schick, and Senior Principle Scientist Simon Wöhrle (Boehringer Ingelheim). The highlight of the programme is the keynote lecture by Brian R. Cairns, Chair of the Oncological Sciences Department at the University of Utah School of Medicine, and an investigator with the Huntsman Cancer Institute (USA).…

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Giulio Superti-Furga and Jean-Pierre Bourguignon at ERC Meeting in Brussels, December 2019

End of ERC Scientific Council Membership Giulio Superti-Furga

At the end of this year, Giulio Superti-Furga, Scientific Director of CeMM and Professor for Medical Systems Biology of the Medical University of Vienna, will terminate his appointment as Member of the Scientific Council of the European Research Council, which he started in January 2017. We thank Giulio for this important scientific community service during difficult political times, strongly advocating for the support of frontier research on new ideas, as the best means to reach innovation and economic welfare, and to sustain the ground for democracy. Having been awarded two ERC Advanced Investigator Grants in the past and two ERC…

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