YearPaper
2012 Abdel-Wahab O, Pardanani A, Bernard OA, Finazzi G, Crispino JD, Gisslinger H, Kralovics R, Odenike O, Bhalla K, Gupta V, Barosi G, Gotlib J, Guglielmelli P, Kiladjian JJ, Noel P, Cazzola M, Vannucchi AM, Hoffman R, Barbui T, Thiele J, Van Etten RA, Mughal T, Tefferi A. Unraveling the genetic underpinnings of myeloproliferative neoplasm and understanding their effect on disease course and response to therapy: proceedings from the 6th International Post-ASH Symposium. Am J Hematol. 2012 May;87(5):562-8. doi: 10.1002/ajh.23169. Epub 2012 Mar 28.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22460584
2012 Adams D, Altucci L, Antonarakis SE, Ballesteros J, Beck S, Bird A, Bock C, Boehm B, Campo E, Caricasole A, Dahl F, Dermitzakis ET, Enver T, Esteller M, Estivill X, Ferguson-Smith A, Fitzgibbon J, Flicek P, Giehl C, Graf T, Grosveld F, Guigo R, Gut I, Helin K, Jarvius J, Kuppers R, Lehrach H, Lengauer T, Lernmark A, Leslie D, Loeffler M, Macintyre E, Mai A, Martens JH, Minucci S, Ouwehand WH, Pelicci PG, Pendeville H, Porse B, Rakyan V, Reik W, Schrappe M, Schubeler D, Seifert M, Siebert R, Simmons D, Soranzo N, Spicuglia S, Stratton M, Stunnenberg HG, Tanay A, Torrents D, Valencia A, Vellenga E, Vingron M, Walter J, Willcocks S. BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol 30, 224-226.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22398613
2012 Amir S, Hartvigsen K, Gonen A, Leibundgut G, Que X, Jensen-Jarolim E, Wagner O, Tsimikas S, Witztum JL, Binder CJ. Peptide mimotopes of malondialdehyde epitopes for clinical applications in cardiovascular disease. J Lipid Res. 2012 Jul;53(7):1316-26. Epub 2012 Apr 16.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22508944
2012 Bento C, Maia TM, Milosevic JD, Carreira IM, Kralovics R, Ribeiro ML. Beta thalassemia major due to acquired uniparental disomy in a previously healthy adolescent. Haematologica. 2012 Aug 8. [Epub ahead of print].
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22875618
2012 Bieghs V, van Gorp PJ, Walenbergh SM, Gijbels MJ, Verheyen F, Buurman WA, Briles DE, Hofker MH, Binder CJ, Shiri-Sverdlov R. Specific immunization strategies against oxidized low-density lipoprotein: A novel way to reduce nonalcoholic steatohepatitis in mice. Hepatology. 2012 Sep;56(3):894-903. doi: 10.1002/hep.25660. Epub 2012 Jul 6.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22334337
2012 Bieghs V, Van Gorp PJ, Wouters K, Hendrikx T, Gijbels MJ, van Bilsen M, Bakker J, Binder CJ, Lutjohann D, Staels B, Hofker MH, Shiri-Sverdlov R. LDL Receptor Knock-Out Mice Are a Physiological Model Particularly Vulnerable to Study the Onset of Inflammation in Non-Alcoholic Fatty Liver Disease. PLoS One 7:e30668.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22295101
2012 Bieghs V, Verheyen F, van Gorp PJ, Hendrikx T, Wouters K, Lütjohann D, Gijbels MJ, Febbraio M, Binder CJ, Hofker MH, Shiri-Sverdlov R. Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells. PLoS One. 2012;7(3):e34378. Epub 2012 Mar 28.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22470565
2012 Bock C, Beerman I, Lien WH, Smith ZD, Gu H, Boyle P, Gnirke A, Fuchs E, Rossi DJ, Meissner A. Genome-scale dynamics of DNA methylation during blood and skin stem cell differentiation. Mol Cell 2012 Aug 24;47(4):633-47.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22841485
2012 Bock C, Lengauer T. Managing drug resistance in cancer: lessons from HIV therapy. Nat Rev Cancer. 2012 Jun 7;12(7):494-501.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22673150
2012 Bock C. Analysing and interpreting DNA methylation data. Nat Rev Genet. 2012 Oct;13(10):705-19.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22986265
2012 Clarke M, Dumon S, Ward C, Jäger R, Freeman S, Dawood B, Sheriff L, Lorvellec M, Kralovics R, Frampton J, García P. MYBL2 haploinsufficiency increases susceptibility to age-related haematopoietic neoplasia. Leukemia. 2012 Aug 22. doi: 10.1038/leu.2012.241.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22910183
2012 Colinge J, Rix U, Bennett KL, Superti-Furga G. Systems biology analysis of protein-drug interactions. Proteomics Clin. Appl. 2012 Jan;6(1-2):102-16.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22213655
2012 Doring Y, Manthey H, Drechsler M, Lievens D, Megens R, Soehnlein O, Busch M, Manca M, Koenen RR, Pelisek J, Daemen MJ, Lutgens E, Zenke M, Binder CJ, Weber C, Zernecke A. Auto-Antigenic Protein-DNA Complexes Stimulate Plasmacytoid Dendritic Cells to Promote Atherosclerosis. Circulation 2012 Apr 3;125(13):1673-83.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22388324
2012 Elsoe S, Ahnstrom J, Christoffersen C, Hoofnagle AN, Plomgaard P, Heinecke JW, Binder CJ, Bjorkbacka H, Dahlback B, Nielsen LB. Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL. Atherosclerosis 221:91-97.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22204862
2012 Fomina-Yadlin D, Kubicek S, Vetere A, Hu He K, Schreiber SL, Wagner BK. GW8510 increases insulin expression in pancreatic alpha cells through activation of p53 transcriptional activity. PLOS one7(1): e28808.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22242153
2012 Frogne T, Sylvestersen KB, Kubicek S, Nielsen ML, Hecksher-Sørensen J. Pdx1 is post-translationally modified in vivo and serine 61 is the principal site of phosphorylation. PLoS One. 2012;7(4):e35233.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22509401
2012 Goncalves A, Karayel E, Rice GI, Bennett KL, Crow YJ, Superti-Furga G, Bürckstümmer T. SAMHD1 is a nucleic acid-binding protein that is mislocalised due to Aicardi-Goutières syndrome-associated mutations. Human Mut. 2012 Jul;33(7):1116-22.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22461318
2012 Guenzl PM, Barlow DP. Macro lncRNAs – a new layer of cis-regulatory information in the mammalian genome. RNA Biology. Jun 1;9(6). [Epub ahead of print].
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22617879
2012 Halachev K, Bast H, Albrecht F, Lengauer T, Bock C. EpiExplorer: live exploration and global analysis of large epigenomic datasets. Genome Biol. 2012 Oct 3;13(10):R96.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23034089
2012 Hantschel O, Grebien F, Superti-Furga G. The growing arsenal of ATP-competitive and allosteric inhibitors of BCR-ABL. Cancer Res. 2012 Oct 1;72(19):4890-5.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23002203
2012 Hantschel O, Superti-Furga G. Cell biology: a key driver of therapeutic innovation. J Cell Biol. 2012 Nov 12;199(4):571-5.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23148230
2012 Hantschel O, Warsch W, Eckelhart E, Kaupe I, Grebien F, Wagner KU, Superti-Furga G, Sexl V. BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia. Nat Chem Biol. 2012 Jan 29;8(3):285-93.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22286129
2012 Harutyunyan AS, Kralovics R. Role of germline genetic factors in MPN pathogenesis. Hematol Oncol Clin North Am. 2012 Oct;26(5):1037-51.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23009936
2012 Heo S, Yang JW, Huber ML, Planyavsky M, Bennett KL, Lubec G. Mass spectrometric characterization of recombinant rat 5-hydroxytryptamine receptor 1A (5-HT(1A) R) expressed in tsA201 human embryonic kidney cells. Proteomics. 2012 Nov;12(22):3338-42.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22997067
2012 Hopkins S, Linderoth E, Hantschel O, Suarez-Henriques P, Pilia G, Kendrick H, Smalley MJ, Superti-Furga G, Ferby I. Mig6 is a sensor of EGF receptor inactivation that directly activates c-Abl to induce apoptosis during epithelial homeostasis. Dev Cell. 2012 Sep 11;23(3):547-59.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22975324
2012 Kachaner D, Filipe J, Laplantine E, Bauch A, Bennett KL, Superti-Furga G, Israël A, Weil R. Plk1-dependent phosphorylation of optineurin provides a negative feedback mechanism for mitotic progression, Mol. Cell. 45, 553-66.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22365832
2012 Knapp S. Animal Models of Sepsis. Section Editor of this issue and Editorial. Drug Discovery Today – Disease Models Jan 2012.
Abstract:
2012 Koerner MV, Pauler FM, Hudson QJ, Santoro F, Sawicka A, Guenzl PM, Stricker SH, Schichl YM, Latos PA, Klement RM, Warczok KE, Wojciechowski J, Seiser C, Kralovics R, Barlow DP. A downstream CpG island controls transcript initiation and elongation and the methylation state of the imprinted Airn macro ncRNA promoter. PLoS Genet. 2012;8(3):e1002540. Epub 2012 Mar 1.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22396659
2012 Kotlarz D, Beier R, Murugan D, Diestelhorst J, Jensen O, Boztug K, Pfeifer D, Kreipe H, Pfister ED, Baumann U, Puchalka J, Bohne J, Egritas O, Dalgic B, Kolho KL, Sauerbrey A, Buderus S, Güngör T, Enninger A, Koda YK, Guariso G, Weiss B, Corbacioglu S, Socha P, Uslu N, Metin A, Wahbeh GT, Husain K, Ramadan D, Al-Herz W, Grimbacher B, Sauer M, Sykora KW, Koletzko S, Klein C. Loss of interleukin-10 signaling and infantile inflammatory bowel disease: implications for diagnosis and therapy. Gastroenterology. 2012 Aug;143(2):347-55.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22549091
2012 Kubicek S, Gilbert JC, Fomina-Yadlin D, Gitlin AD, Yuan Y, Wagner FF, Holson EB, Luo T, Lewis TA, Taylor B, Gupta S, Shamji A, Wagner BK, Clemons PA, Schreiber S.L. Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells. PNAS 2012 Apr 3;109(14):5364-9.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22434908
2012 Latos PA, Pauler FM, Koerner MV, _energin HB, Hudson QJ, Stocsits RR, Allhoff W, Stricker SH, Klement RM, Warczok KE, Aumayr K, Pasierbek P, Barlow DP. Airn transcriptional overlap, but not its lncRNA products, induces imprinted Igf2r silencing. Science. 2012 Dec 14;338(6113):1469-72.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23239737
2012 Lievens D, Habets KL, Robertson AK, Laouar Y, Winkels H, Rademakers T, Beckers L, Wijnands E, Boon L, Mosaheb M, Ait-Oufella H, Mallat Z, Flavell RA, Rudling M, Binder CJ, Gerdes N, Biessen EA, Weber C, Daemen MJ, Kuiper J, Lutgens E. Abrogated transforming growth factor beta receptor II (TGF_RII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis. Eur Heart J. 2012 May 21.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22613345
2012 Litvak V, Ratushny AV, Lampano AE, Schmitz F, Huang AC, Raman A, Rust AG, Bergthaler A, Aitchison JD, Aderem A. A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses. Nature. 2012 Oct 18;490(7420):421-5.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22982991
2012 Maurer M, Müller AC, Wagner C, Huber ML, Rudashevskaya EL, Wagner SN, Bennett KL. Combining Filter-Aided Sample Preparation and Pseudoshotgun Technology To Profile the Proteome of a Low Number of Early Passage Human Melanoma Cells. J Proteome Res. 2012 Dec 24.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23214492
2012 Mekhoubad S, Bock C, Egli D, De Boer S, Kiskinis E, Meissner A, Eggan K. Erosion of Dosage Compensation Impacts Human iPSC Disease Modeling. Cell Stem Cell 2012 May 4;10(5):595-609.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22560080
2012 Mikeska T, Bock C, Do H, Dobrovic A. DNA methylation biomarkers in cancer: progress towards clinical implementation. Expert Review of Molecular Diagnostics. Expert Rev Mol Diagn. 2012 Jun;12(5):473-87.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22702364
2012 Milosevic JD, Kralovics R. Genetic and epigenetic alterations of myeloproliferative disorders. Int J Hematol. 2012 Dec 12. [Epub ahead of print].
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23233154
2012 Milosevic JD, Puda A, Malcovati L, Berg T, Hofbauer M, Stukalov A, Klampfl T, Harutyunyan AS, Gisslinger H, Gisslinger B, Burjanivova T, Rumi E, Pietra D, Elena C, Vannucchi AM, Doubek M, Dvorakova D, Robesova B, Wieser R, Koller E, Suvajdzic N, Tomin D, Tosic N, Colinge J, Racil Z, Steurer M, Pavlovic S, Cazzola M, Kralovics R. Clinical significance of genetic aberrations in secondary acute myeloid leukemia. Am J Hematol. 2012 Nov;87(11):1010-6.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22887079
2012 Müller AC, Breitwieser FP, Fischer H, Schuster C, Brandt O, Colinge J, Superti-Furga G, Stingl G, Elbe-Buerger A, Bennett KL. A comparative proteomic study of human skin suction blister fluid from healthy individuals using immunodepletion and iTRAQ-labelling. J. Proteome Res. 2012 Jul 6;11(7):3715-27.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22578099
2012 Papac-Milicevic N, Breuss JM, Zaujec J, Ryban L, Plyushch T, Wagner GA, Fenzl S, Dremsek P, Cabaravic M, Steiner M, Glass CK, Binder CJ, Uhrin P, Binder BR. The interferon stimulated gene 12 inactivates vasculoprotective functions of NR4A nuclear receptors. Circulation Research. 2012 Apr 13;110(8):e50-63.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22427340
2012 Pauler FM, Barlow DP, Hudson QJ. Mechanisms of long range silencing by imprinted macro non-coding RNAs. Curr Opin Genet Dev. 2012 Jun;22(3):283-9. Epub 2012 Mar 3.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22386265
2012 Pichlmair A, Kandasamy K, Alvisi G, Mulhern O, Sacco R, Habjan M, Binder M, Stefanovic A, Eberle CA, Goncalves A, Bürckstümmer T, Müller AC, Fauster A, Holze C, Lindsten K, Goodbourn S, Kochs G, Weber F, Bartenschlager R, Bowie AG, Bennett KL, Colinge J, Superti-Furga G. Viral immune modulators perturb the human molecular network by common and unique strategies. Nature. 2012 Jul 26;487(7408):486-90.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22810585
2012 Pollreisz A, Funk M, Breitwieser FP, Parapatics K, Sacu S, Georgopoulos M, Dunavoelgyi R, Zlabinger GJ, Colinge J, Bennett KL, Schmidt-Erfurth U. Quantitative proteomics of aqueous and vitreous fluid from patients with idiopathic epiretinal membranes. Exp Eye Res. 2012 Nov 29;108C:48-58.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23201028
2012 Puda A, Milosevic JD, Berg T, Klampfl T, Harutyunyan AS, Gisslinger B, Rumi E, Pietra D, Malcovati L, Elena C, Doubek M, Steurer M, Tosic N, Pavlovic S, Guglielmelli P, Pieri L, Vannucchi AM, Gisslinger H, Cazzola M, Kralovics R. Frequent deletions of JARID2 in leukemic transformation of chronic myeloid malignancies. Am J Hematol. 2012 Mar;87(3):245-50. doi: 10.1002/ajh.22257. Epub 2011 Dec 21.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22190018
2012 Rudashevskaya EL, Sacco R, Kratochwill K, Huber ML, Gstaiger M, Superti-Furga G, Bennett KL. A method to resolve the composition of heterogeneous affinity-purified protein complexes assembled around a common protein by chemical cross-linking, gel electrophoresis and mass spectrometry. Nat Protoc. 2012 Dec 13;8(1):75-97.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23237831
2012 Sage AP, Tsiantoulas D, Baker L, Harrison J, Masters L, Binder CJ, Mallat Z. BAFF (B Cell Activating Factor) Receptor Deficiency Reduces the Development of Atherosclerosis in Mice. Arterioscl Thromb Vasc Biol. 2012 Jul;32(7):1573-6.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22426131
2012 Salzer E, Daschkey S, Choo S, Gombert M, Santos-Valente E, Ginzel S, Schwendinger M, Haas OA, Fritsch G, Pickl WF, Foerster-Waldl E, Borkhardt A, Boztug K*, Bienemann K*, Seidel MG*. Combined immunodeficiency with life-threatening EBV-associatedlymphoproliferative disorder in patients lacking functional CD27. Haematologica. 2013 Mar;98(3):473-8. doi: 10.3324/haematol.2012.068791. Epub 2012 Jul 16. (*equal contributing authors)
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22801960
2012 Santos-Valente E, Reisli I, Artaç H, Ott R, Sanal O, Boztug K. A Novel Mutation in the Complement Component 3 Gene in a Patient with Selective IgA Deficiency. J Clin Immunol. 2013 Jan;33(1):127-33. doi: 10.1007/s10875-012-9775-z. Epub 2012 Sep 21.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22996269#
2012 Sigel S, Bunk S, Meergans T, Doninger B, Stich K, Stulnig T, Derfler K, Hoffmann J, Deininger S, von Aulock S, Knapp S. Apolipoprotein B100 is a suppressor of Staphylococcus aureus-induced innate immune response in humans and mice. Eur J Immunol. 2012 Jul 18. doi: 10.1002/eji.201242564. [Epub ahead of print].
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22806614
2012 Simmer F, Brinkman AB, Assenov Y, Matarese F, Kaan A, Sabatino L, Villanueva A, Huertas D, Esteller M, Lengauer T, Bock C, Colantuoni V, Altucci L, Stunnenberg HG. Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues. Epigenetics. 2012 Dec 1;7(12):1355-67.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23079744
2012 Smida M, Nijman SM. Functional drug-gene interactions in lung cancer. Expert Rev. Mol. Diagn. 2012 Apr;12(3):291-302.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22468819
2012 Stukalov A, Superti-Furga G, Colinge J. Deconvolution of targeted protein-protein interaction maps. J Proteome Res. 2012 Aug 3;11(8):4102-9. Epub 2012 Jul 10.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22724552
2012 Sudol M, Cesareni G, Superti-Furga G, Just W. Special issue – modular protein domains. FEBS Lett. 2012 Aug 14;586(17):2571. Epub 2012 Jun 17.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22713655
2012 Tsiantoulas D, Binder CJ. Natural Antibodies and Atherosclerosis; pp. 289-304 in Inflammation and Atherosclerosis; Springer; Edited by Georg Wick & Cecilia Grundtman.
Abstract:
2012 Uras IZ, List T, Nijman SM. Ubiquitin-Specific Protease 4 Inhibits Mono-Ubiquitination of the Master Growth Factor Signaling Kinase PDK1. PloS One 2012;7(2):e31003.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22347420
2012 Weismann D, Binder CJ. The innate immune response to products of phospholipid peroxidation. Biochim Biophys Acta. 2012 Oct;1818(10):2465-75.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22305963
2012 Winter GE, Rix U, Carlson SM, Gleixner KV, Grebien F, Gridling M, Müller AC, Breitwieser FP, Bilban M, Colinge J, Valent P, Bennett KL, White FM, Superti-Furga G. Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML. Nat Chem Biol. 2012 Nov;8(11):905-12.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23023260
2012 Wolf D, Jehle F, Ortiz Rodriguez A, Dufner B, Hoppe N, Colberg C, Lozhkin A, Bassler N, Rupprecht B, Wiedemann A, Hilgendorf I, Stachon P, Willecke F, Febbraio M, von zur Muhlen C, Binder CJ, Bode C, Zirlik A, Peter K. CD40L deficiency attenuates diet-induced adipose tissue inflammation by impairing immune cell accumulations and production of pathogenic IdG-antibodies. PLoS One. 2012;7(3):e33026. Epub 2012 Mar 8. Erratum in: PLoS One. 2012;7(5): doi/10.1371/annotation/84102aae-770a-41ae-9c15-4736ed129c17. von zur Muhlen, Constantin [added].
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22412980
2012 Yuan Y, Wang Q, Paulk J, Kubicek S, Kemp MM, Adams DJ, Shamji AF, Wagner BK, Schreiber SL. A small-molecule probe of the histone methyltransferase G9a induces cellular senescence in pancreatic adenocarcinoma. ACS Chem Biol. 2012 Jul 20;7(7):1152-7.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22536950
2012 Laimer, D., H. Dolznig, K. Kollmann, P.W. Vesely, M. Schlederer, O. Merkel, A.I. Schiefer, M.R. Hassler, S. Heider, L. Amenitsch, C. Thallinger, P.B. Staber, I. Simonitsch-Klupp, M. Artaker, S. Lagger, S.D. Turner, S. Pileri, P.P. Piccaluga, P. Valent, K. Messana, I. Landra, T. Weichhart, S. Knapp, M. Shehata, M. Todaro, V. Sexl, G. Hofler, R. Piva, E. Medico, B.A. Ruggeri, M. Cheng, R. Eferl, G. Egger, J.M. Penninger, U. Jaeger, R. Moriggl, G. Inghirami, and L. Kenner, PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas. Nat Med, 2012. 18(11): p. 1699-704.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/23064464