YearPaper
2007 Dessing M, Knapp S, Florquin S, de Vos AF, van der Poll T. CD14 facilitates invasive respiratory tract infections by Streptococcus pneumoniae. Am J Respir Crit Care Med. 2007, 175:604–611. 
Abstract: http://www.atsjournals.org/doi/full/10.1164/rccm.200606-824OC#.UrGhL-JHLcY
2007 Gattringer R, Lagler H, Gattringer KB, Knapp S, Burgmann H, et al. Anakinra in two adolescent female patients suffering from colchicineresistant familial Mediterranean fever: effective but risky. Eur J Clin Invest. 2007, 37:912–914.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/17973784
2007 Knapp S, Matt U, Leitinger N, van der Poll T. Oxidized phospholipids inhibit phagocytosis and impair outcome in gram-negative sepsis in vivo. J Immunol. 2007, 178:993–1001.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/17202362
2007 Knapp S. Innate recognition of bacteria. Expert Rev Clin Immunol. 2007, 3:443–445 (Editorial).
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20477147
2008 Filippakopoulos P, Kofler M, Hantschel O, Gish GD, Grebien F, Salah E, Neudecker P, Kay LE, Turk BE, Superti-Furga G, Pawson T, Knapp S. Structural coupling of Fes and Abl SH2-tyrosine kinase domains links substrate recognition and kinase activation. Cell. 2008 Sep 5;134(5): 793–803.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/18775312
2008 Knapp S, von Aulock S, Leendertse M, Haslinger I, Draing C, Golenbock DT, van der Poll T. Lipoteichoic Acid-induced Lung Inflammation depends on TLR2 and the concerted action of TLR4 and Platelet-activating Factor Receptor. Journal of Immunology 2008, 180: 3478–3484.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/18292574
2008 Sharif O, Knapp S. From expression to signaling: Roles of TREM-1 and TREM-2 in innate immunity and bacterial infection. Immunobiology 2008, 213, 701–713.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/18926286
2009 Gröger M, Pasteiner W, Ignatyev G, Matt U, Knapp S, Atrasheuskaya A, Bukin E, Friedl P, Zinkl D, Hofer-Warbinek R, Zacharowski K, Petzelbauer P, Reingruber S. Peptide Bbeta (15-42) preserves endothelial barrier function in shock. PLoS ONE, 2009;4(4): e5391. Epub 2009 Apr 29.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19401765
2009 Lagler H, Sharif O, Haslinger I, Matt U, Stich K, Furtner T, Doninger B, Schmid K, Gattringer R, de Vos AF, Knapp S. TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia. J Immunol, 2009 Aug;183(3): 2027-36. Epub 2009 Jul 13.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19596984
2009 Matt U, Warszawska JM, Bauer M, Dietl W, Mesteri I, Haslinger I, Schabbauer G, Perkmann T, Binder CJ, Reingruber S, Petzelbauer P, Knapp S. B15-42 protects against acid-induced acute lung injury and secondary Pseudomonas pneumonia in vivo. Am J Respir Crit Care Med, 2009 Dec;180(12):1208-17. Epub 2009 Sep 17.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19762562
2009 Moser C, Pohl G, Haslinger I, Knapp S, Rowczenio D, Russel T, Lachmann HJ, Lang U, Kovarik J. Successful treatment of familial Mediterranean fever with Anakinra and outcome after renal transplantation. Nephrol Dial Transplant, 2009 Feb;24(2):676-8.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19033248
2009 von Schlieffen E, Oskolkova OV, Schabbauer G, Gruber F, Blüml S, Genest M, Kadl A, Marsik C, Knapp S, Chow J, Leitinger N, Binder BR, Bochkov VN. Multi-hit inhibition of circulating and cell-associated components of the toll-like receptor 4 pathway by oxidized phospholipids. Arterioscler Thromb Vasc Biol, 2009 Mar; 29(3):356-62. Epub 2008 Dec 26.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19112167
2010 Baumann CL, Aspalter IM, Sharif O, Pichlmair A, Bluml S, Grebien F, Bruckner M, Pasierbek P, Aumayr K, Planyavsky M, Bennett KL, Colinge J, Knapp S, Superti-Furga G. CD14 is a co-receptor of Toll-like receptors 7 and 9. J Exp Med. 2010 Nov 22;207(12):2689-701. Epub 2010 Nov 15.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21078886
2010 Boucheron N, Sharif O, Schebesta A, Croxford A, Raberger J, Schmidt U, Vigl B, Bauer J, Bankoti R, Lassmann H, Epstein MM, Knapp S, Waisman A, Ellmeier W. The protein tyrosine kinase Tec regulates a CD44hiCD62L-Th17 subset. J Immunol. 2010 Nov 1;185(9):5111-9. Epub 2010 Sep 24.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20870948
2010 Bunk S, Sigel S, Metzdorf D, Sharif O, Triantafilou K, Triantafilou M, Hartung T, Knapp S, von Aulock S. Internalization and coreceptor expression are critical for TLR2-mediated recognition of lipoteichoic acid in human peripheral blood. J Immunol. 2010 Sep 15;185(6):3708-17. Epub 2010 Aug 16.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20713893
2010 Guenzl P, Hainzl E, Matt U, Dillinger B, Mahr B, Knapp S, Binder BR, Schabbauer G. Anti-inflammatory properties of the phosphoinositide- 3 kinase (PI3K) pathway are mediated by IL- 10/DUSP regulation. J Leukoc Biol. J Leukoc Biol. 2010 Dec;88(6):1259-69. Epub 2010 Sep 30.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20884649
2010 Knapp S, Frass M. Editorial: Sepsis. Wien Med Wochenschr. 2010 Mar;160(5-6):105-6.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20364411
2010 Knapp S. Update on the role of Toll-like receptors during bacterial infections and sepsis. Wien Med Wochenschr. 2010 Mar;160(5-6):107-11.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20364412
2010 Radwan M, Stiefvater R, Gruner T, Sharif O, Miller I, Marchetti-Deschmann M, Allmaier G, Gemeiner M, Knapp S, Kovarik P, Muller M, Strobl B. Tyrosine kinase 2 controls interleukin-1 production at the translational level. J Immunol. 2010 Sep 15;185(6):3544-53. Epub 2010 Aug 16.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20713887
2010 Schabbauer G, Matt U, Gunzl P, Warszawska J, Furtner T, Hainzl E, Elbau I, Mesteri I, Doninger B, Binder BR, Knapp S. Myeloid PTEN promotes inflammation but impairs bactericidal activities during murine pneumococcal pneumonia. J Immunol. 2010 Jul 1;185(1):468-76. Epub 2010 May 26.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20505137
2011 Gratz N, Hartweger H, Matt U, Kratochvill F, Janos M, Sigel S, Drobits B, Li XD, Knapp S, Kovarik P. Type I interferon production induced by Streptococcus pyogenes-derived nucleic acids is required for host protection. PLoS Pathog. 2011 May;7(5):e1001345.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21625574
2011 Zivkovic A, Sharif O, Stich K, Doninger B, Biaggio M, Colinge J, Bilban M, Mesteri I, Hazemi P, Lemmens-Gruber R, Knapp S. TLR 2 and CD14 mediate innate immunity and lung inflammation to staphylococcal Panton-Valentine leukocidin in vivo. J Immunol. 2011 Feb 1;186(3):1608-17.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21178007
2012 Knapp S. Animal Models of Sepsis. Section Editor of this issue and Editorial. Drug Discovery Today – Disease Models Jan 2012.
Abstract:
2012 Sigel S, Bunk S, Meergans T, Doninger B, Stich K, Stulnig T, Derfler K, Hoffmann J, Deininger S, von Aulock S, Knapp S. Apolipoprotein B100 is a suppressor of Staphylococcus aureus-induced innate immune response in humans and mice. Eur J Immunol. 2012 Jul 18. doi: 10.1002/eji.201242564. [Epub ahead of print].
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22806614
2012 Laimer, D., H. Dolznig, K. Kollmann, P.W. Vesely, M. Schlederer, O. Merkel, A.I. Schiefer, M.R. Hassler, S. Heider, L. Amenitsch, C. Thallinger, P.B. Staber, I. Simonitsch-Klupp, M. Artaker, S. Lagger, S.D. Turner, S. Pileri, P.P. Piccaluga, P. Valent, K. Messana, I. Landra, T. Weichhart, S. Knapp, M. Shehata, M. Todaro, V. Sexl, G. Hofler, R. Piva, E. Medico, B.A. Ruggeri, M. Cheng, R. Eferl, G. Egger, J.M. Penninger, U. Jaeger, R. Moriggl, G. Inghirami, and L. Kenner, PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas. Nat Med, 2012. 18(11): p. 1699-704.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/23064464
2013 Matt U, Sharif O, Martins R, Furtner T, Langeberg L, Gawish R, Elbau I, Zivkovic A, Lakovits A, Oskolkova O, Doninger B, Vychytil A, Perkmann T, Schabbauer G, Binder CJ, Bochkov VN, Scott JD, Knapp S. WAVE1 mediates suppression of phagocytosis by phospholipid-derived DAMPs. J Clin Invest. 2013 July 1; 123(7): 3014–3024. .
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23934128
2013 Warszawska JM, Gawish R, Sharif O, Sigel S, Doninger B, Lakovits K, Mesteri I, Nairz M, Boon L, Spiel A, Fuhrmann V, Strobl B, Müller M, Schenk P, Weiss G, Knapp S. Lipocalin 2 deactivates macrophages and worsens pneumococcal pneumonia outcomes. J Clin Invest. 2013 August 1; 123(8).
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23863624
2013 Zielinski C, Knapp S, Mascaux C, Hirsch F. Rationale for targeting the immune system through checkpoint molecule blockade in the treatment of non-small-cell lung cancer. Ann Oncol. 2013 May; 24(5): 1170–1179.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23393121
2013 Sharif O, Matt U, Saluzzo S, Lakovits K, Haslinger I, Furtner T, Doninger B, Knapp S. The scavenger receptor CD36 downmodulates the early inflammatory response while enhancing bacterial phagocytosis during pneumococcal pneumonia.J Immunol. 2013 Jun 1;190(11):5640-8. doi: 10.4049/jimmunol.1202270. Epub 2013 Apr 22.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23610144
2013 Bürckstümmer T, Banning C, Hainzl P, Schobesberger R, Kerzendorfer C, Pauler FM, Chen D, Them N, Schischlik F, Rebsamen M, Smida M, Fece de la Cruz F, Lapao A, Liszt M, Eizinger B, Guenzl PM, Blomen VA, Konopka T, Gapp B, Parapatics K, Maier B, Stöckl J, Fischl W, Salic S, Taba Casari MR, Knapp S, Bennett KL, Bock C, Colinge J, Kralovics R, Ammerer G, Casari G, Brummelkamp TR, Superti-Furga G, Nijman SM. A reversible gene trap collection empowers haploid genetics in human cells. Nat Methods. 2013 Oct;10(10):965-71.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24161985
2013 Knapp, S., Diabetes and infection: is there a link?--A mini-review. Gerontology, 2013. 59(2): p. 99-104.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/23182884
2014 Jais A, Einwallner E, Sharif O, Gossens K, Lu TT, Soyal SM, Medgyesi D, Neureiter D, Paier-Pourani J, Dalgaard K, Duvigneau JC, Lindroos-Christensen J, Zapf TC, Amann S, Saluzzo S, Jantscher F, Stiedl P, Todoric J, Martins R, Oberkofler H, Müller S, Hauser-Kronberger C, Kenner L, Casanova E, Sutterlüty-Fall H, Bilban M, Miller K, Kozlov AV, Krempler F, Knapp S, Lumeng CN, Patsch W, Wagner O, Pospisilik JA, Esterbauer H. Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man. Cell. 2014 Jul 3;158(1):25-40. doi: 10.1016/j.cell.2014.04.043.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24995976
2014 Köffel R, Meshcheryakova A, Warszawska J, Hennig A, Wagner K, Jörgl A, Gubi D, Moser D, Hladik A, Hoffmann U, Fischer MB, van den Berg W, Koenders M, Scheinecker C, Gesslbauer B, Knapp S, Strobl H. Monocytic cell differentiation from band-stage neutrophils under inflammatory conditions via MKK6 activation. Blood. 2014 Sep 11. pii: blood-2014-07-588178.[Epub ahead of print]
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25214442
2014 Sharif O, Gawish R, Warszawska JM, Martins R, Lakovits K, Hladik A, Doninger B, Brunner J, Korosec A, Schwarzenbacher RE, Berg T, Kralovics R, Colinge J, Mesteri I, Gilfillan S, Salmaggi A, Verschoor A, Colonna M, Knapp S. The triggering receptor expressed on myeloid cells 2 inhibits complement component 1q effector mechanisms and exerts detrimental effects during pneumococcal pneumonia. PLoS Pathog. 2014 Jun 12;10(6):e1004167. doi: 10.1371/journal.ppat.1004167. eCollection 2014.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24945405
2015 Heinz LX, Baumann CL, Köberlin MS, Snijder B, Gawish R, Shui G, Sharif O, Aspalter IM, Müller AC, Kandasamy RK, Breitwieser FP, Pichlmair A, Bruckner M, Rebsamen M, Blüml S, Karonitsch T, Fauster A, Colinge J, Bennett KL, Knapp S, Wenk MR, Superti-Furga G. The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity. Cell Rep. 2015 Jun 30;11(12):1919-28. doi: 10.1016/j.celrep.2015.05.006.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/26095358
2015 Kulinski TM, Casari MR, Guenzl PM, Wenzel D, Andergassen D, Hladik A, Datlinger P, Farlik M, Theussl HC, Penninger JM, Knapp S, Bock C, Barlow DP, Hudson QJ. Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern. Dev Biol. 2015 Jun 15;402(2):291-305. doi: 10.1016/j.ydbio.2015.04.010. Epub 2015 Apr 24.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25912690
2015 Blatt K, Cerny-Reiterer S, Schwaab J, Sotlar K, Eisenwort G, Stefanzl G, Hoermann G, Mayerhofer M, Schneeweiss M, Knapp S, Rülicke T, Hadzijusufovic E, Bauer K, Smiljkovic D, Willmann M, Reiter A, Horny HP, Valent P. Identification of the Ki-1 antigen (CD30) as a novel therapeutic target in systemic mastocytosis. Blood. 2015 Oct 20. pii: blood-2015-03-637728.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/26486787
2015 Prochazkova J, Sakaguchi S, Owusu M, Mazouzi A, Wiedner M, Velimezi G, Moder M, Turchinovich G, Hladik A, Gurnhofer E, Hayday A, Behrens A, Knapp S, Kenner L, Ellmeier W, Loizou JI. DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation. PLoS Genet. 2015 Nov 6;11(11):e1005645. doi: 10.1371/journal.pgen.1005645. eCollection 2015.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/26544571
2015 Schliehe, C., E.K. Flynn, B. Vilagos, U. Richson, S. Swaminathan, B. Bosnjak, L. Bauer, R.K. Kandasamy, I.M. Griesshammer, L. Kosack, F. Schmitz, V. Litvak, J. Sissons, A. Lercher, A. Bhattacharya, K. Khamina, A.L. Trivett, L. Tessarollo, I. Mesteri, A. Hladik, D. Merkler, S. Kubicek, S. Knapp, M.M. Epstein, D.E. Symer, A. Aderem, and A. Bergthaler, The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection. Nat Immunol, 2015. 16(1): p. 67-74.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25419628
2015 Matt, U., O. Sharif, R. Martins, and S. Knapp, Accumulating evidence for a role of oxidized phospholipids in infectious diseases. Cell Mol Life Sci, 2015. 72(6): p. 1059-71.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25410378
2015 Gawish, R., R. Martins, B. Bohm, T. Wimberger, O. Sharif, K. Lakovits, M. Schmidt, and S. Knapp, Triggering receptor expressed on myeloid cells-2 fine-tunes inflammatory responses in murine Gram-negative sepsis. FASEB J, 2015. 29(4): p. 1247-57.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25477281
2016 Doehn JM, Winkler A, Kuzmina Z, Hladik A, Greinix H, Knapp S, Robak O. Pentraxin-3 levels in graft-versus-host disease during allogeneic hematopoietic stem cell transplantation. Exp Hematol. 2016 Jul 9. pii: S0301-472X(16)30460-X.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/27403536
2016 Kral JB, Kuttke M, Schrottmaier WC, Birnecker B, Warszawska J, Wernig C, Paar H, Salzmann M, Sahin E, Brunner JS, Österreicher C, Knapp S, Assinger A, Schabbauer G. Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways. Sci Rep. 2016 Mar 14;6:23034. doi: 10.1038/srep23034.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/26971883
2016 Maier BB, Hladik A, Lakovits K, Korosec A, Martins R, Kral JB, Mesteri I, Strobl B, Müller M, Kalinke U, Merad M, Knapp S. Type I interferon promotes alveolar epithelial type II cell survival during pulmonary Streptococcus pneumoniae infection and sterile lung injury in mice. Eur J Immunol. 2016 Sep;46(9):2175-86. doi: 10.1002/eji.201546201.
Abstract: http://onlinelibrary.wiley.com/doi/10.1002/eji.201546201/abstract
2016 Martins R, Maier J, Gorki AD, Huber KV, Sharif O, Starkl P, Saluzzo S, Quattrone F, Gawish R, Lakovits K, Aichinger MC, Radic-Sarikas B, Lardeau CH, Hladik A, Korosec A, Brown M, Vaahtomeri K, Duggan M, Kerjaschki D, Esterbauer H, Colinge J, Eisenbarth SC, Decker T, Bennett KL, Kubicek S, Sixt M, Superti-Furga G, Knapp S. Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions. Nat Immunol. 2016 Oct 31. doi: 10.1038/ni.3590.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/27798618
2016 Mukai K, Tsai M, Starkl P, Marichal T, Galli SJ. IgE and mast cells in host defense against parasites and venoms. Semin Immunopathol. 2016 Sep;38(5):581-603. doi: 10.1007/s00281-016-0565-1. Review.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/27225312
2016 Reber LL, Gaudenzio N, Starkl P, Galli SJ. Neutrophils are not required for resolution of acute gouty arthritis in mice. Nat Med. 2016 Dec 6;22(12):1382-1384. doi: 10.1038/nm.4216.
Abstract: http://www.nature.com/nm/journal/v22/n12/full/nm.4216.html
2016 Sibilano R, Gaudenzio N, DeGorter MK, Reber LL, Hernandez JD, Starkl PM, Zurek OW, Tsai M, Zahner S, Montgomery SB, Roers A, Kronenberg M, Yu M, Galli SJ. A TNFRSF14-Fc_RI-mast cell pathway contributes to development of multiple features of asthma pathology in mice. Nat Commun. 2016 Dec 16;7:13696. doi: 10.1038/ncomms13696.
Abstract: http://www.nature.com/articles/ncomms13696
2016 Willmann KL, Sacco R, Martins R, Garncarz W, Krolo A, Knapp S, Bennett KL, Boztug K. Expanding the Interactome of the Noncanonical NF-_B Signaling Pathway. J Proteome Res. 2016 Sep 2;15(9):2900-9. doi: 10.1021/acs.jproteome.5b01004.
Abstract: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295629/
2016 Knapp, S., Gut to lung. Gut, 2016. 65(4): p. 544-5.
Abstract: http://gut.bmj.com/content/65/4/544
2016 Castiglia, V., A. Piersigilli, F. Ebner, M. Janos, O. Goldmann, U. Dambock, A. Kroger, S. Weiss, S. Knapp, A.M. Jamieson, C. Kirschning, U. Kalinke, B. Strobl, M. Muller, D. Stoiber, S. Lienenklaus, and P. Kovarik, Type I Interferon Signaling Prevents IL-1beta-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue. Cell Host Microbe, 2016. 19(3): p. 375-87.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26962946
2017 Simona Saluzzo, Anna-Dorothea Gorki, Batika M.J. Rana, Rui Martins, Seth Scanlon, Philipp Starkl, Karin Lakovits, Anastasiya Hladik, Ana Korosec, Omar Sharif, Joanna M. Warszawska, Helen Jolin, Ildiko Mesteri, Andrew N.J. McKenzie, Sylvia Knapp. First-Breath-Induced Type 2 Pathways Shape the Lung Immune Environment. Cell Rep. 2017 Feb 21; 18(8): 1893–1905. DOI:http://dx.doi.org/10.1016/j.celrep.2017.01.071.
Abstract: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329122/